GR3026516T3 - Inhalation powders and method of manufacturing them. - Google Patents

Inhalation powders and method of manufacturing them.

Info

Publication number
GR3026516T3
GR3026516T3 GR980400700T GR980400700T GR3026516T3 GR 3026516 T3 GR3026516 T3 GR 3026516T3 GR 980400700 T GR980400700 T GR 980400700T GR 980400700 T GR980400700 T GR 980400700T GR 3026516 T3 GR3026516 T3 GR 3026516T3
Authority
GR
Greece
Prior art keywords
pct
inhalation powders
sec
manufacturing
particle size
Prior art date
Application number
GR980400700T
Other languages
English (en)
Inventor
Klaus Arnold
Peter Grass
Adolf Knecht
Robert Roos
Gerhard Sluke
Herbert Thieme
Joachim Wenzel
Original Assignee
Boehringer Ingelheim Int
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=6446712&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GR3026516(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim Int, Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Int
Publication of GR3026516T3 publication Critical patent/GR3026516T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Otolaryngology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR980400700T 1991-12-10 1998-04-03 Inhalation powders and method of manufacturing them. GR3026516T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4140689A DE4140689B4 (de) 1991-12-10 1991-12-10 Inhalationspulver und Verfahren zu ihrer Herstellung
PCT/EP1992/002814 WO1993011746A1 (de) 1991-12-10 1992-12-05 Inhalationspulver und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
GR3026516T3 true GR3026516T3 (en) 1998-07-31

Family

ID=6446712

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400700T GR3026516T3 (en) 1991-12-10 1998-04-03 Inhalation powders and method of manufacturing them.

Country Status (12)

Country Link
US (1) US5478578A (el)
EP (1) EP0663815B1 (el)
JP (1) JP3567329B2 (el)
AT (1) ATE164060T1 (el)
AU (1) AU670555B2 (el)
CA (1) CA2125685C (el)
DE (2) DE4140689B4 (el)
DK (1) DK0663815T3 (el)
ES (1) ES2116353T3 (el)
GR (1) GR3026516T3 (el)
NZ (1) NZ246047A (el)
WO (1) WO1993011746A1 (el)

Families Citing this family (95)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993025198A1 (en) * 1992-06-12 1993-12-23 Teijin Limited Ultrafine powder for inhalation and production thereof
SE9203743D0 (sv) * 1992-12-11 1992-12-11 Astra Ab Efficient use
JPH07165613A (ja) * 1993-10-19 1995-06-27 Dot:Kk 経鼻吸収薬物用キャリヤおよび生理活性ペプチド組成物
GB9322014D0 (en) * 1993-10-26 1993-12-15 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
AUPM411494A0 (en) * 1994-02-25 1994-03-24 Central Sydney Area Health Service Method and device for the provocation of upper or lower airway narrowing and/or the induction of sputum
GB9408053D0 (en) * 1994-04-22 1994-06-15 Nat Heart & Lung Inst Pharmaceutical preparation
DE4425255A1 (de) 1994-07-16 1996-01-18 Asta Medica Ag Formulierung zur inhalativen Applikation
WO1996002275A1 (fr) * 1994-07-20 1996-02-01 Toyama Chemical Co., Ltd. Onguent buccal a liberation prolongee
GB9501841D0 (en) 1995-01-31 1995-03-22 Co Ordinated Drug Dev Improvements in and relating to carrier particles for use in dry powder inhalers
US5747002A (en) * 1995-04-05 1998-05-05 Genentech, Inc. Preparation of sodium chloride aerosol formulations
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US5881720A (en) * 1997-04-29 1999-03-16 The Procter & Gamble Company Method of delivering halotherapy
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
SE9803770D0 (sv) * 1998-11-05 1998-11-05 Astra Ab Dry powder pharmaceutical formulation
EP1283036B2 (de) 1998-11-13 2020-01-01 Jagotec AG Multidosis-Trockenpulverinhalator mit Pulverreservoir
US20070212422A1 (en) * 1999-11-10 2007-09-13 Manfred Keller Dry powder for inhalation
ITMI991582A1 (it) 1999-07-16 2001-01-16 Chiesi Farma Spa Polveri costituite da particelle aventi la superficie perfettamente levigata da utilizzare come veicoli per la preparazione di miscele inala
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
EP1129705A1 (en) 2000-02-17 2001-09-05 Rijksuniversiteit te Groningen Powder formulation for inhalation
DE60128902T2 (de) * 2000-04-17 2008-02-14 Vectura Ltd., Chippenham Formulierungen zur verwendung in inhalationsvorrichtungen
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
PE20011227A1 (es) 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
GB0009468D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formulations for use in inhaler devices
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
GB0014851D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
UA75375C2 (en) * 2000-10-12 2006-04-17 Boehringer Ingelheim Pharma Method for producing powdery preparations for inhaling
UA72014C2 (en) * 2000-10-12 2005-01-17 Boehringer Ingelheim Pharma Tiotropium-containing powdery preparations for inhalations intended for treating asthma and chronic obstructive pulmonary disease (variants), method for their production and capsule
DK2283817T3 (en) 2000-11-30 2016-09-05 Vectura Ltd Process for preparing particles for use in a pharmaceutical composition
US20030070679A1 (en) * 2001-06-01 2003-04-17 Boehringer Ingelheim Pharma Kg Capsules containing inhalable tiotropium
US6681768B2 (en) 2001-06-22 2004-01-27 Sofotec Gmbh & Co. Kg Powder formulation disintegrating system and method for dry powder inhalers
DE10141376A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Inhalationspulvern
DE10141377A1 (de) * 2001-08-23 2003-03-13 Boehringer Ingelheim Pharma Aufstreuverfahren zur Herstellung von Pulverformulierungen
AU2002333644A1 (en) * 2001-09-17 2003-04-01 Glaxo Group Limited Dry powder medicament formulations
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
EP1458360B1 (en) 2001-12-19 2011-05-11 Novartis AG Pulmonary delivery of aminoglycosides
US7309707B2 (en) * 2002-03-20 2007-12-18 Boehringer Ingelheim Pharma Gmbh & Co. Kg Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament
FI116657B (fi) * 2002-03-28 2006-01-31 Focus Inhalation Oy Menetelmä kantoainehiukkasten käsittelemiseksi ja niiden käyttö
US7763280B2 (en) 2002-11-28 2010-07-27 Boehringer Ingelheim Pharma Gmbh & Co. Kg Tiotropium containing powder formulation for inhalation
DE10255387A1 (de) * 2002-11-28 2004-06-09 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Tiotropium-haltige Pulverformulierung für die Inhalation
US20040121003A1 (en) * 2002-12-19 2004-06-24 Acusphere, Inc. Methods for making pharmaceutical formulations comprising deagglomerated microparticles
US20040226556A1 (en) 2003-05-13 2004-11-18 Deem Mark E. Apparatus for treating asthma using neurotoxin
WO2005004845A1 (en) 2003-07-11 2005-01-20 Glaxo Group Limited Pharmaceutical formulations comprising magnesium stearate
GB0327723D0 (en) * 2003-09-15 2003-12-31 Vectura Ltd Pharmaceutical compositions
BRPI0509348A (pt) 2004-04-21 2007-09-11 Innovata Biomed Ltd inalador
MXPA06012240A (es) 2004-04-23 2007-01-31 Cydex Inc Formulacion para inhalador de polvo seco que contiene eter sulfoalquilico-ciclodextrina.
DE102004048390A1 (de) * 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Neue Pulverinhalativa auf Basis modifizierter Laktosemischungen als Hilfsstoff
DE102004048389A1 (de) * 2004-10-01 2006-04-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Modifizierung von Oberflächen von Laktose als Hilfsstoff zur Verwendung für Pulverinhalativa
WO2006086270A1 (en) 2005-02-10 2006-08-17 Glaxo Group Limited Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
AU2006247053B2 (en) 2005-05-18 2013-05-23 Horizon Therapeutics U.S. Holding Llc Aerosolized fluoroquinolones and uses thereof
US7629331B2 (en) 2005-10-26 2009-12-08 Cydex Pharmaceuticals, Inc. Sulfoalkyl ether cyclodextrin compositions and methods of preparation thereof
US8483831B1 (en) 2008-02-15 2013-07-09 Holaira, Inc. System and method for bronchial dilation
KR101719824B1 (ko) 2008-05-09 2017-04-04 호라이라 인코포레이티드 기관지나무 치료용 시스템, 어셈블리 및 방법
DK2346509T3 (da) 2008-10-07 2020-08-03 Horizon Orphan Llc Inhalation af levofloxacin til at reducere lungeinflammation
BRPI0920026B1 (pt) 2008-10-07 2023-11-07 Horizon Orphan Llc Composição farmacêutica e respectivos usos
TWI491416B (zh) * 2008-12-24 2015-07-11 Daiichi Sankyo Co Ltd 吸入用乾燥粉末醫藥組成物
EP2221048A1 (en) * 2009-02-18 2010-08-25 Siegfried Generics International AG Pharmaceutical composition for inhalation
EP4403231A2 (en) 2009-02-26 2024-07-24 Glaxo Group Limited Pharmaceutical formulations comprising 4-{(1 r)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol
IN2012DN02477A (el) 2009-09-04 2015-08-21 Mpex Pharmaceuticals Inc
EP2926757B1 (en) 2009-10-27 2023-01-25 Nuvaira, Inc. Delivery devices with coolable energy emitting assemblies
MD4039C1 (ro) * 2009-11-05 2010-12-31 Институт Химии Академии Наук Молдовы Microsalină artificială de suprafaţă
US8911439B2 (en) 2009-11-11 2014-12-16 Holaira, Inc. Non-invasive and minimally invasive denervation methods and systems for performing the same
AU2010319477A1 (en) 2009-11-11 2012-05-24 Holaira, Inc. Systems, apparatuses, and methods for treating tissue and controlling stenosis
MD4089C1 (ro) * 2009-11-18 2011-08-31 Институт Химии Академии Наук Молдовы Halocameră artificială de suprafaţă
GB0921075D0 (en) 2009-12-01 2010-01-13 Glaxo Group Ltd Novel combination of the therapeutic agents
MD4040C1 (ro) * 2009-12-09 2010-12-31 Институт Химии Академии Наук Молдовы Halocameră artificială de suprafaţă
JP5878475B2 (ja) * 2009-12-14 2016-03-08 シエシー ファルマセウティチィ ソシエタ ペル アチオニ 吸入用抗生物質微粒子
TR200909788A2 (tr) 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Tiotropyum içeren inhalasyona uygun kuru toz formülasyonu
RU2012138909A (ru) * 2010-03-31 2014-05-10 Гленмарк Фармасьютикалс Лимитед Фармацевтическая порошковая композиция для ингаляций
WO2012106382A1 (en) 2011-01-31 2012-08-09 Genoa Pharmaceuticals, Inc. Aerosol pirfenidone and pyridone analog compounds and uses thereof
US8992987B2 (en) 2011-04-06 2015-03-31 Dow Global Technologies Llc Polysaccharide derivatives and dosage forms
JP2015155379A (ja) * 2012-05-23 2015-08-27 杏林製薬株式会社 吸入粉末剤及びその製造方法
JP5087182B1 (ja) * 2012-06-13 2012-11-28 クリニプロ株式会社 吸入用パウダーの製造方法
US20150150802A1 (en) * 2012-07-05 2015-06-04 Arven Ilac Sanayi Ve Ticaret Anonim Sirketi Dry powder inhaler compositions comprising long acting muscarinic antagonists
US10111957B2 (en) * 2012-07-05 2018-10-30 Arven Ilac Snayi ve Ticaret A.S. Inhalation compositions comprising glucose anhydrous
WO2014007781A2 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Inhalation compositions
US10105316B2 (en) 2012-07-05 2018-10-23 Arven llac Sanayi Ve Ticaret A.S. Inhalation compositions comprising muscarinic receptor antagonist
US9398933B2 (en) 2012-12-27 2016-07-26 Holaira, Inc. Methods for improving drug efficacy including a combination of drug administration and nerve modulation
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
PL2821061T3 (pl) 2013-07-01 2018-05-30 Arven Ilac Sanayi Ve Ticaret A.S. Nowe preparaty do inhalacji
CN104274426A (zh) * 2013-07-03 2015-01-14 陆克塞纳医药公司 昂丹司琼细粉、昂丹司琼气溶胶组合物及其用途
CN104274427A (zh) * 2013-07-03 2015-01-14 陆克塞纳医药公司 格拉司琼气溶胶组合物及其用途
AU2014296032A1 (en) 2013-07-31 2016-03-17 Windward Pharma, Inc. Aerosol tyrosine kinase inhibitor compounds and uses thereof
WO2015054280A1 (en) * 2013-10-08 2015-04-16 Lam Therapeutics, Inc. Rapamycin for the treatment of lymphangioleiomyomatosis
UA118861C2 (uk) * 2013-12-06 2019-03-25 Оріон Корпорейшн Спосіб отримання сухих порошкових композицій для інгаляцій
NZ722927A (en) 2014-01-10 2022-07-29 Avalyn Pharma Inc Aerosol pirfenidone and pyridone analog compounds and uses thereof
US10307371B2 (en) * 2014-02-11 2019-06-04 AI Therapeutics, Inc. Rapamycin for the treatment of lymphangioleiomyomatosis
HRP20230863T1 (hr) 2014-04-04 2023-11-10 AI Therapeutics, Inc. Inhalacijska formulacija rapamicina, namijenjena liječenju stanja povezanih sa starenjem
MX2017004440A (es) 2014-10-07 2017-11-01 Lam Therapeutics Inc Una formulacion de rapamicina inhalable para el tratamiento de hipertension pulmonar.
PT3175842T (pt) 2015-12-03 2020-03-04 Tiefenbacher Alfred E Gmbh & Co Kg Processo de mistura de pó seco
GB201911517D0 (en) * 2019-08-12 2019-09-25 Verona Pharma Plc Pharmaceutical composition
CA3150240A1 (en) 2019-09-24 2021-04-01 Tomaso GUIDI Dry powder formulation for a dry powder inhaler, with a combination of spheronised particles and coarse particles, and a dry powder inhaler comprising the formulation
WO2022240897A1 (en) 2021-05-10 2022-11-17 Sepelo Therapeutics, Llc Pharmaceutical composition comprising delafloxacin for administration into the lung
WO2023028364A1 (en) 2021-08-27 2023-03-02 Sepelo Therapeutics, Llc Targeted compositions and uses therof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2533065A (en) * 1947-03-08 1950-12-05 George V Taplin Micropulverized therapeutic agents
US3957965A (en) * 1967-08-08 1976-05-18 Fisons Limited Sodium chromoglycate inhalation medicament
GB1242211A (en) * 1967-08-08 1971-08-11 Fisons Pharmaceuticals Ltd Pharmaceutical composition
GB1410588A (en) * 1971-08-10 1975-10-22 Fisons Ltd Composition

Also Published As

Publication number Publication date
CA2125685C (en) 2005-11-08
DK0663815T3 (da) 1998-10-07
ATE164060T1 (de) 1998-04-15
DE4140689A1 (de) 1993-06-17
WO1993011746A1 (de) 1993-06-24
EP0663815B1 (de) 1998-03-18
NZ246047A (en) 1997-03-24
DE59209244D1 (de) 1998-04-23
AU670555B2 (en) 1996-07-25
EP0663815A1 (de) 1995-07-26
ES2116353T3 (es) 1998-07-16
JP3567329B2 (ja) 2004-09-22
DE4140689B4 (de) 2007-11-22
AU3085492A (en) 1993-07-19
CA2125685A1 (en) 1993-06-24
US5478578A (en) 1995-12-26
JPH08501056A (ja) 1996-02-06

Similar Documents

Publication Publication Date Title
GR3026516T3 (en) Inhalation powders and method of manufacturing them.
GB9606677D0 (en) Process and device
EP0951917A3 (en) Particle delivery of particularly a powdered therapeutical agent
MY115688A (en) Pharmaceutical composition for administration by inhalation
HK1031680A1 (en) Perforated microparticles and methods of use
EP0831782A4 (en) METHOD AND SYSTEM FOR TREATING DISPERSABLE FINE POWDER
ZA929919B (en) Powder inhaler.
IL110314A0 (en) Preparations for stimulating the circulation and their preparation
EP2298279A3 (en) Pharmaceutical compositions for inhalation
WO2003024396A3 (en) Dry powder medicament formulations
GB9410222D0 (en) Medicaments
TNSN05048A1 (en) Inhalation compositions with high drug ratios
EP0319557A4 (en) Reconstituted hdl particles and uses thereof
HK1038310A1 (en) Compositions and methods for treating intracellular infections.
NZ513981A (en) Delivery of microparticle formulations using needleless syringe device for sustained-release of bioactive compounds
SI1699434T1 (sl) Postopek za pripravo zdravila