GR3024274T3 - Anti cd-4 antibodies blocking hiv-induced syncytia - Google Patents

Anti cd-4 antibodies blocking hiv-induced syncytia

Info

Publication number
GR3024274T3
GR3024274T3 GR970401923T GR970401923T GR3024274T3 GR 3024274 T3 GR3024274 T3 GR 3024274T3 GR 970401923 T GR970401923 T GR 970401923T GR 970401923 T GR970401923 T GR 970401923T GR 3024274 T3 GR3024274 T3 GR 3024274T3
Authority
GR
Greece
Prior art keywords
antibodies blocking
aids
antibody homologs
blocking hiv
induced syncytia
Prior art date
Application number
GR970401923T
Other languages
Greek (el)
English (en)
Inventor
Linda C Burkly
Patricia L Chisholm
David W Thomas
Margaret D Rosa
Joseph J Rosa
Original Assignee
Biogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biogen Inc filed Critical Biogen Inc
Publication of GR3024274T3 publication Critical patent/GR3024274T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR970401923T 1990-11-27 1997-07-30 Anti cd-4 antibodies blocking hiv-induced syncytia GR3024274T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61854290A 1990-11-27 1990-11-27
PCT/US1991/008843 WO1992009305A1 (en) 1990-11-27 1991-11-27 Anti cd-4 antibodies blocking hiv-induced syncytia

Publications (1)

Publication Number Publication Date
GR3024274T3 true GR3024274T3 (en) 1997-10-31

Family

ID=24478147

Family Applications (1)

Application Number Title Priority Date Filing Date
GR970401923T GR3024274T3 (en) 1990-11-27 1997-07-30 Anti cd-4 antibodies blocking hiv-induced syncytia

Country Status (12)

Country Link
US (1) US5871732A (https=)
EP (1) EP0512112B1 (https=)
JP (5) JPH05505112A (https=)
AT (1) ATE153536T1 (https=)
AU (1) AU662891B2 (https=)
CA (1) CA2073031C (https=)
DE (1) DE69126301T2 (https=)
DK (1) DK0512112T3 (https=)
ES (1) ES2101834T3 (https=)
GR (1) GR3024274T3 (https=)
OA (1) OA10079A (https=)
WO (1) WO1992009305A1 (https=)

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US10894087B2 (en) 2010-12-22 2021-01-19 Nektar Therapeutics Multi-arm polymeric prodrug conjugates of cabazitaxel-based compounds
US20140088021A1 (en) 2011-05-27 2014-03-27 Nektar Therapeutics Water-Soluble Polymer-Linked Binding Moiety and Drug Compounds
CA2832109C (en) 2011-06-10 2021-07-06 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
CN102321653B (zh) * 2011-07-18 2013-11-20 清华大学 人鼠嵌合型cd4质粒及其多抗在抑制hiv感染中的应用
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US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
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US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
RU2762315C2 (ru) 2014-09-16 2021-12-17 Юнайтед Байофарма, Инк. Лечение и функциональное излечение вич-инфекции моноклональными антителами к cd4, опосредующими конкурентное ингибирование входа вич
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EP3072901A1 (en) 2015-03-23 2016-09-28 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
HK1253694A1 (zh) 2015-06-01 2019-06-28 Medigene Immunotherapies Gmbh T细胞受体文库
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US9925258B2 (en) 2015-10-02 2018-03-27 International Aids Vaccine Initiative Replication-competent VSV-HIV Env vaccines
HUE053674T2 (hu) 2015-12-23 2021-07-28 Medigene Immunotherapies Gmbh Antigén-specifikus TCR receptorok új generációja
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CN112175087B (zh) * 2019-07-02 2022-05-13 深圳市迈加瑞生物技术有限公司 一种抗CD4和TGFβ的双特异性抗体、其药物组合及其用途
TWI845745B (zh) * 2019-08-19 2024-06-21 洛克菲勒大學 具改良藥物動力學之經酸鹼度依賴性抗原結合活性工程化之抗人類免疫缺乏病毒抗體
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Also Published As

Publication number Publication date
ATE153536T1 (de) 1997-06-15
ES2101834T3 (es) 1997-07-16
JP2007175055A (ja) 2007-07-12
AU9154391A (en) 1992-06-25
AU662891B2 (en) 1995-09-21
JP2007151556A (ja) 2007-06-21
CA2073031A1 (en) 1992-05-28
US5871732A (en) 1999-02-16
EP0512112A1 (en) 1992-11-11
HK1007686A1 (en) 1999-04-23
DE69126301T2 (de) 1998-01-02
JP2005041859A (ja) 2005-02-17
OA10079A (en) 1996-12-18
EP0512112B1 (en) 1997-05-28
JP2002356499A (ja) 2002-12-13
JP4642035B2 (ja) 2011-03-02
DK0512112T3 (da) 1997-09-29
WO1992009305A1 (en) 1992-06-11
JPH05505112A (ja) 1993-08-05
CA2073031C (en) 2002-10-01
DE69126301D1 (de) 1997-07-03

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