GR3020902T3 - Use of 15-keto-prostaglandin compound for improvement of encephalic function - Google Patents

Use of 15-keto-prostaglandin compound for improvement of encephalic function

Info

Publication number
GR3020902T3
GR3020902T3 GR960402122T GR960402122T GR3020902T3 GR 3020902 T3 GR3020902 T3 GR 3020902T3 GR 960402122 T GR960402122 T GR 960402122T GR 960402122 T GR960402122 T GR 960402122T GR 3020902 T3 GR3020902 T3 GR 3020902T3
Authority
GR
Greece
Prior art keywords
keto
improvement
prostaglandin compound
encephalic
function
Prior art date
Application number
GR960402122T
Other languages
English (en)
Inventor
Ryuji Ueno
Hiroyoshi Osama
Tomio Oda
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8543990A external-priority patent/JPH07116135B2/ja
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Publication of GR3020902T3 publication Critical patent/GR3020902T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
GR960402122T 1989-11-22 1996-08-29 Use of 15-keto-prostaglandin compound for improvement of encephalic function GR3020902T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30383989 1989-11-22
JP761190 1990-01-17
JP8543990A JPH07116135B2 (ja) 1990-03-30 1990-03-30 6,15―ジケト―5―ハロプロスタグランジンe類

Publications (1)

Publication Number Publication Date
GR3020902T3 true GR3020902T3 (en) 1996-11-30

Family

ID=27277677

Family Applications (1)

Application Number Title Priority Date Filing Date
GR960402122T GR3020902T3 (en) 1989-11-22 1996-08-29 Use of 15-keto-prostaglandin compound for improvement of encephalic function

Country Status (9)

Country Link
US (3) US5117042A (el)
EP (1) EP0435443B1 (el)
KR (2) KR0147057B1 (el)
AT (1) ATE141793T1 (el)
CA (1) CA2030345C (el)
DE (1) DE69028289T2 (el)
DK (1) DK0435443T3 (el)
ES (1) ES2093636T3 (el)
GR (1) GR3020902T3 (el)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2851704B2 (ja) * 1993-02-03 1999-01-27 帝人株式会社 脳血栓症治療のための薬学的組成物
HU223345B1 (hu) 1995-12-20 2004-08-30 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Eljárás alfa, béta-telítetlen ketonok sztereoszelektív redukciójára
DK0857718T3 (da) * 1996-06-10 2002-12-16 Sucampo Ag Endothelinantagonist
US6680339B2 (en) 1996-11-12 2004-01-20 Alcon Manufacturing, Ltd. 15-fluoro prostaglandins as ocular hypotensives
JP4248022B2 (ja) 1996-11-12 2009-04-02 アルコン ラボラトリーズ,インコーポレイテッド 眼圧降下剤としての15―フルオロプロスタグランジン
PL339212A1 (en) * 1997-09-09 2000-12-04 Procter & Gamble Aromatic c16-c20-substituted tetrahydroprostaglandines useful as fp agonists
SK3382000A3 (en) * 1997-09-09 2000-10-09 Procter & Gamble A compound having structure of aromatic substituted prostaglandins and its use for the treatment of bone disorders
PT978284E (pt) * 1997-11-28 2008-10-07 Sucampo Ag Utilização de compostos 15-ceto-prostaglandina-e como antagonistas da endotelina
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ C16不飽和fp−選択的プロスタグランジン類縁体
AR026046A1 (es) 1999-10-15 2002-12-26 R Tech Ueno Ltd NUEVA COMPOSICIoN Y MÉTODO PARA ESTABILIZAR LA MISMA
NZ521464A (en) 2000-03-24 2004-09-24 Sucampo Ag Apoptosis inhibiting composition comprising a 15-keto-prostaglandin or derivative thereof
US20020013294A1 (en) * 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020037914A1 (en) * 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
US20020172693A1 (en) * 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
TWI263505B (en) * 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
ES2375082T3 (es) 2005-01-27 2012-02-24 Sucampo Ag Composición para el tratamiento de trastornos del sistema nervioso central.
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
US8513441B2 (en) * 2008-08-29 2013-08-20 Alphora Research Inc. Prostaglandin synthesis and intermediates for use therein
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
WO2010083597A1 (en) 2009-01-22 2010-07-29 Apotex Pharmachem Inc. Methods of making lubiprostone and intermediates thereof
US8592483B2 (en) 2011-08-05 2013-11-26 Sucampo Ag Method for treating schizophrenia
CN104140410B (zh) * 2013-05-09 2017-12-15 江苏豪森药业集团有限公司 鲁比前列酮的制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153858A3 (en) * 1984-02-29 1985-12-11 The Upjohn Company The therapeutic use of prostaglandins
JPS62198616A (ja) * 1986-02-24 1987-09-02 Res Dev Corp Of Japan 脳血流量改善・脳細胞保護剤
CA1322749C (en) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
ES2038289T3 (es) * 1987-05-15 1993-07-16 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Utilizacion de 15-ceto-pges para la fabricacion de un medicamento para aumentar la temperatura corporal.
ATE82499T1 (de) * 1987-09-18 1992-12-15 R Tech Ueno Ltd Okulare hypotensivagenzien.
DE3873007T2 (de) * 1987-10-02 1992-12-03 Ueno Seiyaku Oyo Kenkyujo Kk Kathartica.
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
JP2597649B2 (ja) * 1988-05-11 1997-04-09 株式会社上野製薬応用研究所 気管・気管支拡張剤
EP0343904B1 (en) * 1988-05-23 1993-04-28 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Hypersphyxia causing composition
US5106809A (en) * 1990-12-14 1992-04-21 Exxon Research And Engineering Company High activity, high yield tin modified platinum-iridium catalysts, and reforming process utilizing such catalysts

Also Published As

Publication number Publication date
EP0435443A3 (en) 1993-01-27
EP0435443B1 (en) 1996-08-28
ES2093636T3 (es) 1997-01-01
CA2030345A1 (en) 1991-05-23
DE69028289D1 (de) 1996-10-02
KR0147057B1 (ko) 1998-08-17
EP0435443A2 (en) 1991-07-03
US5117042A (en) 1992-05-26
CA2030345C (en) 1998-12-08
US5426115A (en) 1995-06-20
ATE141793T1 (de) 1996-09-15
DE69028289T2 (de) 1997-01-09
US5290811A (en) 1994-03-01
KR910009269A (ko) 1991-06-28
DK0435443T3 (da) 1996-09-16
KR0167745B1 (ko) 1999-01-15

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