ATE141793T1 - Verwendung von 15-keto-prostaglandin zur verbesserung der encephalischen funktion - Google Patents

Verwendung von 15-keto-prostaglandin zur verbesserung der encephalischen funktion

Info

Publication number
ATE141793T1
ATE141793T1 AT90312642T AT90312642T ATE141793T1 AT E141793 T1 ATE141793 T1 AT E141793T1 AT 90312642 T AT90312642 T AT 90312642T AT 90312642 T AT90312642 T AT 90312642T AT E141793 T1 ATE141793 T1 AT E141793T1
Authority
AT
Austria
Prior art keywords
keto
prostaglandin
improve
encephalic
function
Prior art date
Application number
AT90312642T
Other languages
English (en)
Inventor
Ryuji Ueno
Hiroyoshi Osama
Tomio Oda
Original Assignee
R Tech Ueno Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP8543990A external-priority patent/JPH07116135B2/ja
Application filed by R Tech Ueno Ltd filed Critical R Tech Ueno Ltd
Application granted granted Critical
Publication of ATE141793T1 publication Critical patent/ATE141793T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT90312642T 1989-11-22 1990-11-21 Verwendung von 15-keto-prostaglandin zur verbesserung der encephalischen funktion ATE141793T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30383989 1989-11-22
JP761190 1990-01-17
JP8543990A JPH07116135B2 (ja) 1990-03-30 1990-03-30 ６，１５―ジケト―５―ハロプロスタグランジンｅ類

Publications (1)

Publication Number Publication Date
ATE141793T1 true ATE141793T1 (de) 1996-09-15

Family

ID=27277677

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90312642T ATE141793T1 (de) 1989-11-22 1990-11-21 Verwendung von 15-keto-prostaglandin zur verbesserung der encephalischen funktion

Country Status (9)

Country Link
US (3) US5117042A (de)
EP (1) EP0435443B1 (de)
KR (2) KR0147057B1 (de)
AT (1) ATE141793T1 (de)
CA (1) CA2030345C (de)
DE (1) DE69028289T2 (de)
DK (1) DK0435443T3 (de)
ES (1) ES2093636T3 (de)
GR (1) GR3020902T3 (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100255992B1 (ko) * 1993-02-03 2000-05-01 우에하라 아끼라 뇌혈전증 치료를 위한 약학적 조성물
HU223345B1 (hu) 1995-12-20 2004-08-30 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Eljárás alfa, béta-telítetlen ketonok sztereoszelektív redukciójára
ES2182088T3 (es) * 1996-06-10 2003-03-01 Sucampo Ag Antagonista de la endotelina.
US6680339B2 (en) 1996-11-12 2004-01-20 Alcon Manufacturing, Ltd. 15-fluoro prostaglandins as ocular hypotensives
DE69705421T2 (de) 1996-11-12 2002-05-16 Alcon Laboratories, Inc. 15-fluoro-prostaglandine als augendrucksenkende mittel
IL134839A0 (en) * 1997-09-09 2001-05-20 Procter & Gamble Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
DK1012137T3 (da) * 1997-09-09 2003-03-10 Procter & Gamble Aromatiske C-16-C-20-substituerede tetrahydro-prostaglandiner og deres anvendelse som prostaglandin FP-agonister
ATE401894T1 (de) * 1997-11-28 2008-08-15 Sucampo Ag Verwendung von 15-keto-prostaglandin-e verbindungen als endothelin antagonisten
WO2000051980A1 (en) 1999-03-05 2000-09-08 The Procter & Gamble Company C16 unsaturated fp-selective prostaglandins analogs
BRPI0014869B8 (pt) * 1999-10-15 2021-05-25 Sucampo Ag prostaglandinas bicíclicas, composições estabilizadas das mesmas, bem como processo para sua estabilização
JP2003527430A (ja) * 2000-03-24 2003-09-16 スカンポ・アクチェンゲゼルシャフト １５−ケトプロスタグランジンまたはその誘導体を含むアポトーシス抑制剤
US20020146439A1 (en) * 2000-03-31 2002-10-10 Delong Mitchell Anthony Compositions and methods for treating hair loss using oximyl and hydroxylamino prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020037914A1 (en) * 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US6414016B1 (en) 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI331920B (en) * 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
US7732487B2 (en) * 2001-11-19 2010-06-08 Sucampo Ag Method for treating a disease or condition responsive to opening of C1C-2 channel
CA2595898C (en) * 2005-01-27 2015-04-28 Sucampo Ag Method and composition for treating central nervous system disorders
US20060281818A1 (en) * 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
US8513441B2 (en) * 2008-08-29 2013-08-20 Alphora Research Inc. Prostaglandin synthesis and intermediates for use therein
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8623918B2 (en) * 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
CA2750487A1 (en) 2009-01-22 2010-07-29 Apotex Pharmachem Inc. Methods of making lubiprostone and intermediates thereof
JP6193230B2 (ja) 2011-08-05 2017-09-06 スキャンポ・アーゲーＳｕｃａｍｐｏ ＡＧ 統合失調症の処置方法
CN104140410B (zh) * 2013-05-09 2017-12-15 江苏豪森药业集团有限公司 鲁比前列酮的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153858A3 (de) * 1984-02-29 1985-12-11 The Upjohn Company Therapeutische Anwendung von Protaglandinen
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
CA1322749C (en) * 1987-01-28 1993-10-05 Ryuzo Ueno Prostaglandins of the d series, and tranquilizers and soporifics containing the same
CA1324129C (en) * 1987-04-30 1993-11-09 Ryuzo Ueno Prostaglandins of the f series
DE3869471D1 (de) * 1987-05-15 1992-04-30 Ueno Seiyaku Oyo Kenkyujo Kk Fiebersteigende zusammensetzung.
GB2209939B (en) * 1987-09-18 1992-01-02 R Tech Ueno Ltd The use of 13,14-dihydro-15-keto-prostaglandins as ocular hypotensive agents
EP0310305B1 (de) * 1987-10-02 1992-07-22 Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo Kathartica
JP2597649B2 (ja) * 1988-05-11 1997-04-09 株式会社上野製薬応用研究所 気管・気管支拡張剤
AU619543B2 (en) * 1988-05-11 1992-01-30 Sucampo Ag Use of 15-ketoprostaglandin e or f compounds for uterine contraction
DE68906193T2 (de) * 1988-05-23 1993-08-05 Ueno Seiyaku Oyo Kenkyujo Kk Hypersphyxia verursachende zusammensetzung.
US5106809A (en) * 1990-12-14 1992-04-21 Exxon Research And Engineering Company High activity, high yield tin modified platinum-iridium catalysts, and reforming process utilizing such catalysts

Also Published As

Publication number Publication date
US5426115A (en) 1995-06-20
US5117042A (en) 1992-05-26
KR910009269A (ko) 1991-06-28
DE69028289T2 (de) 1997-01-09
EP0435443A3 (en) 1993-01-27
KR0167745B1 (ko) 1999-01-15
US5290811A (en) 1994-03-01
DE69028289D1 (de) 1996-10-02
CA2030345C (en) 1998-12-08
KR0147057B1 (ko) 1998-08-17
EP0435443A2 (de) 1991-07-03
DK0435443T3 (da) 1996-09-16
ES2093636T3 (es) 1997-01-01
EP0435443B1 (de) 1996-08-28
CA2030345A1 (en) 1991-05-23
GR3020902T3 (en) 1996-11-30

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EEIH Change in the person of patent owner
EELA Cancelled due to lapse of time