GR3002596T3 - 2-guanidino-4-arylthiazoles for treatment of peptic ulcers - Google Patents

2-guanidino-4-arylthiazoles for treatment of peptic ulcers

Info

Publication number
GR3002596T3
GR3002596T3 GR91401225T GR910401225T GR3002596T3 GR 3002596 T3 GR3002596 T3 GR 3002596T3 GR 91401225 T GR91401225 T GR 91401225T GR 910401225 T GR910401225 T GR 910401225T GR 3002596 T3 GR3002596 T3 GR 3002596T3
Authority
GR
Greece
Prior art keywords
optionally substituted
guanidino
treatment
arylthiazoles
alkyl
Prior art date
Application number
GR91401225T
Other languages
English (en)
Inventor
John Lawrence Lamattina
Peter Andrew Mccarthy
Lawrence Alan Reiter
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of GR3002596T3 publication Critical patent/GR3002596T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
GR91401225T 1986-08-29 1991-08-22 2-guanidino-4-arylthiazoles for treatment of peptic ulcers GR3002596T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8601795 1986-08-29

Publications (1)

Publication Number Publication Date
GR3002596T3 true GR3002596T3 (en) 1993-01-25

Family

ID=22195621

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91401225T GR3002596T3 (en) 1986-08-29 1991-08-22 2-guanidino-4-arylthiazoles for treatment of peptic ulcers

Country Status (10)

Country Link
US (1) US5026715A (el)
EP (1) EP0259085B1 (el)
JP (1) JPH0633258B2 (el)
AT (1) ATE66477T1 (el)
DE (1) DE3772301D1 (el)
DK (1) DK451687A (el)
ES (1) ES2031514T3 (el)
GR (1) GR3002596T3 (el)
IE (1) IE60039B1 (el)
PT (1) PT85604B (el)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6313156B1 (en) * 1999-12-23 2001-11-06 Icos Corporation Thiazole compounds as cyclic-AMP-specific phosphodiesterase inhibitors
DE102004008141A1 (de) * 2004-02-19 2005-09-01 Abbott Gmbh & Co. Kg Guanidinverbindungen und ihre Verwendung als Bindungspartner für 5-HT5-Rezeptoren
ES2402362T3 (es) 2004-09-30 2013-05-03 Takeda Pharmaceutical Company Limited Inhibidores de la bomba de protones
SI2327692T1 (sl) 2005-08-30 2012-11-30 Tekeda Pharmaceutical Company Ltd heterociklilsulfonil aminometil hetero arilno substituirani H pirolni derivati kot inhibitorji izločanja kisline
WO2007114338A1 (ja) 2006-03-31 2007-10-11 Takeda Pharmaceutical Company Limited 酸分泌抑制薬
US8933105B2 (en) * 2007-02-28 2015-01-13 Takeda Pharmaceutical Company Limited Pyrrole compounds
WO2010021149A1 (ja) * 2008-08-21 2010-02-25 武田薬品工業株式会社 酸分泌抑制スピロ化合物
US8969387B2 (en) 2008-08-27 2015-03-03 Takeda Pharmaceutical Company Limited Pyrrole compounds
MX355415B (es) * 2011-06-07 2018-04-18 Clevexel Pharma Composiciones y metodos para tratar enfermedades y trastornos que son modulados por una vía de transducción de señales.

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3591584A (en) * 1968-08-27 1971-07-06 Pfizer Benzothiazine dioxides
CA963908A (en) * 1971-01-29 1975-03-04 David B. Capps Thiazolium salts
US3758491A (en) * 1972-01-07 1973-09-11 Parke Davis & Co Novel anti infective agents and means of producing the same
IE47458B1 (en) * 1977-11-07 1984-03-21 Leo Pharm Prod Ltd Quinolylguanidine derivatives
US4374843A (en) * 1980-10-14 1983-02-22 Pfizer Inc. 2-Guanidino-4-heteroarylthiazoles
US4435396A (en) * 1982-05-10 1984-03-06 Pfizer Inc. Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor
JPS59225186A (ja) * 1983-05-18 1984-12-18 Yamanouchi Pharmaceut Co Ltd 新規なグアニジノチアゾ−ル誘導体及びその製造方法
JPS59225172A (ja) * 1983-06-03 1984-12-18 Yamanouchi Pharmaceut Co Ltd 新規グアニジノチアゾ−ル誘導体及びその製法
US4560690A (en) * 1984-04-30 1985-12-24 Pfizer Inc. 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents
US4791200A (en) * 1987-06-22 1988-12-13 Ortho Pharmaceutical Corporation 2-substituted-4-aryl-substituted thiazoles

Also Published As

Publication number Publication date
US5026715A (en) 1991-06-25
IE60039B1 (en) 1994-05-18
ES2031514T3 (es) 1992-12-16
DK451687A (da) 1988-05-13
JPS6363678A (ja) 1988-03-22
PT85604B (pt) 1990-05-31
IE872277L (en) 1988-02-29
DE3772301D1 (de) 1991-09-26
EP0259085B1 (en) 1991-08-21
DK451687D0 (da) 1987-08-28
EP0259085A1 (en) 1988-03-09
PT85604A (en) 1987-09-01
JPH0633258B2 (ja) 1994-05-02
ATE66477T1 (de) 1991-09-15

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