GR3002267T3 - Dissymmetrical 1,4-dihydropyridine-3,5-dicarboxylic-acid derivatives, preparation processes and therapeutical use - Google Patents

Dissymmetrical 1,4-dihydropyridine-3,5-dicarboxylic-acid derivatives, preparation processes and therapeutical use

Info

Publication number
GR3002267T3
GR3002267T3 GR91400959T GR910400959T GR3002267T3 GR 3002267 T3 GR3002267 T3 GR 3002267T3 GR 91400959 T GR91400959 T GR 91400959T GR 910400959 T GR910400959 T GR 910400959T GR 3002267 T3 GR3002267 T3 GR 3002267T3
Authority
GR
Greece
Prior art keywords
group
dicarboxylic
dissymmetrical
dihydropyridine
acid derivatives
Prior art date
Application number
GR91400959T
Other languages
English (en)
Inventor
Jacques Robin
Didier Pruneau
Francois Bellamy
Original Assignee
Fournier Innovation Synergie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fournier Innovation Synergie filed Critical Fournier Innovation Synergie
Publication of GR3002267T3 publication Critical patent/GR3002267T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/113—Spiro-condensed systems with two or more oxygen atoms as ring hetero atoms in the oxygen-containing ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Coloring (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Laminated Bodies (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
  • Plural Heterocyclic Compounds (AREA)
GR91400959T 1986-04-02 1991-07-05 Dissymmetrical 1,4-dihydropyridine-3,5-dicarboxylic-acid derivatives, preparation processes and therapeutical use GR3002267T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8604685A FR2596760B1 (fr) 1986-04-02 1986-04-02 Derives dissymetriques de l'acide 1,4-dihydropyridine-3,5-dicarboxylique, procedes de preparation et utilisation en therapeutique

Publications (1)

Publication Number Publication Date
GR3002267T3 true GR3002267T3 (en) 1992-12-30

Family

ID=9333794

Family Applications (1)

Application Number Title Priority Date Filing Date
GR91400959T GR3002267T3 (en) 1986-04-02 1991-07-05 Dissymmetrical 1,4-dihydropyridine-3,5-dicarboxylic-acid derivatives, preparation processes and therapeutical use

Country Status (25)

Country Link
US (2) US4806544A (el)
EP (1) EP0240398B1 (el)
JP (1) JPS6317883A (el)
KR (1) KR900005956B1 (el)
CN (1) CN1015460B (el)
AT (1) ATE63555T1 (el)
AU (2) AU590690B2 (el)
CS (1) CS268828B2 (el)
DD (2) DD278793A5 (el)
DE (1) DE3770037D1 (el)
DK (1) DK161787A (el)
ES (1) ES2028886T3 (el)
FI (1) FI86302C (el)
FR (1) FR2596760B1 (el)
GR (1) GR3002267T3 (el)
HU (2) HUT53080A (el)
IL (1) IL81933A (el)
NO (1) NO167029C (el)
NZ (1) NZ219758A (el)
OA (1) OA08508A (el)
PT (1) PT84560B (el)
SU (1) SU1586515A3 (el)
TN (1) TNSN87043A1 (el)
YU (2) YU57287A (el)
ZA (1) ZA872258B (el)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0506801A1 (de) * 1989-12-22 1992-10-07 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue dihydropyridine
DE4125271A1 (de) * 1991-07-31 1993-02-11 Bayer Ag Neue n-alkylierte 1,4-dihydropyridindicarbonsaeureester
WO1993006082A1 (en) * 1991-09-13 1993-04-01 Merck & Co., Inc. Process for the preparation of 4-substituted-1,4-dihydropyridines
US8841296B2 (en) 2009-03-27 2014-09-23 Council of Scientific and Industrial Research, Anusandhan Bhawan, Rafi Marg Substituted 1, 4-dioxa-8-azaspiro[4,5]decanes useful as fungicides and a process for the preparation thereof
WO2012123966A1 (en) 2011-03-04 2012-09-20 Arch Pharmalabs Limited Process for the preparation of 4 -substituted -1, 4-dihydropyridines
CN102796111B (zh) * 2012-09-10 2014-09-24 贵州大学 氧氮杂螺环酰胺基团的羧(磺)酸酯类化合物及制备方法和用途
CN104860873A (zh) * 2015-05-28 2015-08-26 石家庄学院 一种(s)-1,4-二氢吡啶钙离子拮抗剂的制备方法
WO2017063307A1 (zh) * 2015-10-13 2017-04-20 山东轩竹医药科技有限公司 1，4-二氢吡啶-3，5-二羧酸酯衍生物的制备方法及中间体

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
GB1245087A (en) * 1967-10-26 1971-09-02 Wyeth John & Brother Ltd Heterocyclic compounds
JPS4932542B1 (el) * 1970-08-17 1974-08-31
GB1591089A (en) * 1976-12-17 1981-06-10 Fujisawa Pharmaceutical Co 1,4-dihydropyridine derivatives and process for preparation thereof
US4250312A (en) * 1979-12-28 1981-02-10 Argus Chemical Corp. Process for preparing 4-piperidone spiroketal compounds
US4250313A (en) * 1980-02-01 1981-02-10 Argus Chemical Corp. Process for preparing 4-piperidone spiroketal compounds
DE3208628A1 (de) * 1982-03-10 1983-09-22 Bayer Ag, 5090 Leverkusen Neue verbindungen, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
WO1983003249A1 (en) * 1982-03-17 1983-09-29 Yoshitomi Pharmaceutical 1,4-dihydropyridine-3,5-dicarboxylate derivatives
JPS58159462A (ja) * 1982-03-17 1983-09-21 Yoshitomi Pharmaceut Ind Ltd １，４−ジヒドロピリジン−３，５−ジカルボン酸エステル誘導体
FR2577552B1 (fr) * 1985-02-20 1987-09-04 Sori Soc Rech Ind Esters heterocycliques dissymetriques d'acides 1,4-dihydropyridine-3,5-dicarboxyliques, procede de preparation et utilisation en therapeutique

Also Published As

Publication number Publication date
JPS6317883A (ja) 1988-01-25
SU1586515A3 (ru) 1990-08-15
KR900005956B1 (ko) 1990-08-18
EP0240398B1 (fr) 1991-05-15
CS268828B2 (en) 1990-04-11
DK161787D0 (da) 1987-03-30
PT84560A (fr) 1987-04-01
HU199479B (en) 1990-02-28
DK161787A (da) 1987-10-03
IL81933A (en) 1991-06-30
US4806544A (en) 1989-02-21
YU44714B (en) 1990-12-31
FR2596760B1 (fr) 1988-12-09
FI871316A0 (fi) 1987-03-25
NO167029B (no) 1991-06-17
DD278793A5 (de) 1990-05-16
AU590690B2 (en) 1989-11-09
NZ219758A (en) 1989-04-26
NO871339D0 (no) 1987-03-31
CN87102452A (zh) 1987-10-14
AU610753B2 (en) 1991-05-23
ATE63555T1 (de) 1991-06-15
PT84560B (pt) 1989-11-30
YU48088A (en) 1988-12-31
NO167029C (no) 1991-09-25
YU57287A (en) 1988-10-31
FR2596760A1 (fr) 1987-10-09
OA08508A (fr) 1988-07-29
EP0240398A1 (fr) 1987-10-07
HUT53080A (en) 1990-09-28
DE3770037D1 (de) 1991-06-20
CN1015460B (zh) 1992-02-12
ES2028886T3 (es) 1992-07-16
FI871316A (fi) 1987-10-03
FI86302C (fi) 1992-08-10
TNSN87043A1 (fr) 1990-01-01
ZA872258B (en) 1987-11-25
FI86302B (fi) 1992-04-30
HUT49613A (en) 1989-10-30
AU7041087A (en) 1987-10-08
CS229287A2 (en) 1989-08-14
IL81933A0 (en) 1987-10-20
AU4126389A (en) 1989-12-21
DD263291A5 (de) 1988-12-28
KR870010055A (ko) 1987-11-30
NO871339L (no) 1987-10-05
US4900833A (en) 1990-02-13

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