GEP20043386B - β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the Same - Google Patents
β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the SameInfo
- Publication number
- GEP20043386B GEP20043386B GE3744A GEAP1998003744A GEP20043386B GE P20043386 B GEP20043386 B GE P20043386B GE 3744 A GE3744 A GE 3744A GE AP1998003744 A GEAP1998003744 A GE AP1998003744A GE P20043386 B GEP20043386 B GE P20043386B
- Authority
- GE
- Georgia
- Prior art keywords
- amyloid peptide
- proteins
- same
- binding proteins
- polynucleotides encoding
- Prior art date
Links
- 102000040430 polynucleotide Human genes 0.000 title abstract 2
- 108091033319 polynucleotide Proteins 0.000 title abstract 2
- 239000002157 polynucleotide Substances 0.000 title abstract 2
- 102000013455 Amyloid beta-Peptides Human genes 0.000 title 1
- 108010090849 Amyloid beta-Peptides Proteins 0.000 title 1
- 102000023856 peptide binding proteins Human genes 0.000 title 1
- 108091008399 peptide binding proteins Proteins 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 102000004169 proteins and genes Human genes 0.000 abstract 4
- 208000024827 Alzheimer disease Diseases 0.000 abstract 2
- DZHSAHHDTRWUTF-SIQRNXPUSA-N amyloid-beta polypeptide 42 Chemical compound C([C@@H](C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(O)=O)[C@@H](C)CC)C(C)C)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1N=CNC=1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(C)C)C1=CC=CC=C1 DZHSAHHDTRWUTF-SIQRNXPUSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Hospice & Palliative Care (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6458397P | 1997-04-16 | 1997-04-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GEP20043386B true GEP20043386B (en) | 2004-02-10 |
Family
ID=22056941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GE3744A GEP20043386B (en) | 1997-04-16 | 1998-04-14 | β -Amyloid Peptide-Binding Proteins and Polynucleotides Encoding the Same |
Country Status (18)
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7005295B1 (en) | 1997-04-16 | 2006-02-28 | Wyeth | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
| US6787319B2 (en) * | 1997-04-16 | 2004-09-07 | American Home Products Corp. | β-amyloid peptide-binding proteins and polynucleotides encoding the same |
| NZ510997A (en) * | 1998-10-13 | 2004-01-30 | Wyeth Corp | G-protein-coupled receptor-like proteins, polynucleotides encoded by them, and methods of using same |
| US6455082B1 (en) * | 1999-04-26 | 2002-09-24 | Nestec S.A. | Shelf-stable calcium fortified milk and dairy products |
| CA2387646A1 (en) * | 1999-10-21 | 2001-04-26 | Kalobios, Inc. | A general method for optimizing the expression of heterologous proteins |
| US8663650B2 (en) | 2003-02-21 | 2014-03-04 | Ac Immune Sa | Methods and compositions comprising supramolecular constructs |
| US7807171B2 (en) | 2003-07-25 | 2010-10-05 | Ac Immune Sa | Therapeutic vaccine targeted against P-glycoprotein 170 for inhibiting multidrug resistance in the treatment of cancers |
| EP3527220A1 (en) | 2010-08-12 | 2019-08-21 | AC Immune S.A. | Vaccine engineering |
| WO2012055933A1 (en) | 2010-10-26 | 2012-05-03 | Ac Immune S.A. | Liposome-based construct comprising a peptide modified through hydrophobic moieties |
| CN102060912B (zh) * | 2010-11-22 | 2012-11-14 | 清华大学 | 淀粉样蛋白寡聚体构象型抗原表位多肽及其应用 |
| CN111320678B (zh) * | 2020-03-09 | 2023-06-09 | 安亭生物有限责任公司 | 抗菌肽突变体及其应用 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0779702B2 (ja) * | 1986-11-17 | 1995-08-30 | サイオス ノバ インコーポレイテッド | 組換えアルツハイマーアミロイドタンパク |
| IL115743A0 (en) * | 1994-10-28 | 1996-01-19 | American Nat Red Cross | A mammal with cells containing a transgene and its production |
| US5786180A (en) * | 1995-02-14 | 1998-07-28 | Bayer Corporation | Monoclonal antibody 369.2B specific for β A4 peptide |
-
1998
- 1998-04-14 WO PCT/US1998/007462 patent/WO1998046636A2/en active Application Filing
- 1998-04-14 GE GE3744A patent/GEP20043386B/en unknown
- 1998-04-14 JP JP54419698A patent/JP2001523093A/ja active Pending
- 1998-04-14 AU AU71156/98A patent/AU740445B2/en not_active Ceased
- 1998-04-14 EE EEP199900482A patent/EE9900482A/xx unknown
- 1998-04-14 EP EP98918186A patent/EP0975753A2/en not_active Withdrawn
- 1998-04-14 KR KR1019997009480A patent/KR20010006393A/ko not_active Ceased
- 1998-04-14 CN CNA200510052975XA patent/CN1690203A/zh active Pending
- 1998-04-14 BR BR9808562-0A patent/BR9808562A/pt not_active Application Discontinuation
- 1998-04-14 EA EA199900941A patent/EA004256B1/ru not_active IP Right Cessation
- 1998-04-14 CA CA002286484A patent/CA2286484A1/en not_active Abandoned
- 1998-04-14 IL IL13223698A patent/IL132236A0/xx active IP Right Grant
- 1998-04-14 SK SK1432-99A patent/SK143299A3/sk unknown
- 1998-04-14 ID IDW991187D patent/ID24914A/id unknown
- 1998-04-14 NZ NZ500216A patent/NZ500216A/xx unknown
- 1998-04-14 UA UA99116193A patent/UA72875C2/uk unknown
- 1998-04-14 HU HU0003116A patent/HUP0003116A3/hu unknown
- 1998-04-14 CN CNB988043173A patent/CN1196785C/zh not_active Expired - Fee Related
-
1999
- 1999-10-06 IL IL132236A patent/IL132236A/en not_active IP Right Cessation
- 1999-10-15 NO NO995062A patent/NO995062L/no not_active Application Discontinuation
-
2006
- 2006-11-05 IL IL179047A patent/IL179047A0/en unknown
-
2007
- 2007-12-28 JP JP2007339660A patent/JP2008104465A/ja active Pending
-
2008
- 2008-06-18 JP JP2008159606A patent/JP2008253275A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN1268973A (zh) | 2000-10-04 |
| HUP0003116A3 (en) | 2003-03-28 |
| IL132236A0 (en) | 2001-03-19 |
| WO1998046636A3 (en) | 1999-01-28 |
| NO995062L (no) | 1999-12-14 |
| WO1998046636A2 (en) | 1998-10-22 |
| CN1196785C (zh) | 2005-04-13 |
| BR9808562A (pt) | 2000-05-23 |
| CA2286484A1 (en) | 1998-10-22 |
| SK143299A3 (en) | 2000-09-12 |
| AU740445B2 (en) | 2001-11-01 |
| EA004256B1 (ru) | 2004-02-26 |
| EP0975753A2 (en) | 2000-02-02 |
| EE9900482A (enrdf_load_html_response) | 2000-06-15 |
| CN1690203A (zh) | 2005-11-02 |
| AU7115698A (en) | 1998-11-11 |
| NZ500216A (en) | 2001-06-29 |
| JP2001523093A (ja) | 2001-11-20 |
| ID24914A (id) | 2000-08-31 |
| UA72875C2 (uk) | 2005-05-16 |
| IL132236A (en) | 2007-03-08 |
| HUP0003116A2 (hu) | 2001-01-29 |
| NO995062D0 (no) | 1999-10-15 |
| KR20010006393A (ko) | 2001-01-26 |
| JP2008253275A (ja) | 2008-10-23 |
| IL179047A0 (en) | 2007-03-08 |
| JP2008104465A (ja) | 2008-05-08 |
| EA199900941A1 (ru) | 2000-06-26 |
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