GEP20043323B - C10 Carbonate Substituted Taxanes as Antitumor Agents - Google Patents

C10 Carbonate Substituted Taxanes as Antitumor Agents

Info

Publication number
GEP20043323B
GEP20043323B GE4523A GEAP2001004523A GEP20043323B GE P20043323 B GEP20043323 B GE P20043323B GE 4523 A GE4523 A GE 4523A GE AP2001004523 A GEAP2001004523 A GE AP2001004523A GE P20043323 B GEP20043323 B GE P20043323B
Authority
GE
Georgia
Prior art keywords
antitumor agents
carbonate substituted
substituted taxanes
taxanes
carbonate
Prior art date
Application number
GE4523A
Other languages
English (en)
Inventor
Robert A Holton
Original Assignee
Univ Florida State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida State Res Found filed Critical Univ Florida State Res Found
Publication of GEP20043323B publication Critical patent/GEP20043323B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00Containers or packages with special means for dispensing contents
    • B65D83/14Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/75Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GE4523A 2000-02-02 2001-02-02 C10 Carbonate Substituted Taxanes as Antitumor Agents GEP20043323B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17978200P 2000-02-02 2000-02-02

Publications (1)

Publication Number Publication Date
GEP20043323B true GEP20043323B (en) 2004-02-10

Family

ID=22657972

Family Applications (1)

Application Number Title Priority Date Filing Date
GE4523A GEP20043323B (en) 2000-02-02 2001-02-02 C10 Carbonate Substituted Taxanes as Antitumor Agents

Country Status (25)

Country Link
EP (1) EP1165553B1 (https=)
JP (1) JP2003522172A (https=)
CN (1) CN1380882A (https=)
AT (1) ATE432928T1 (https=)
AU (1) AU782150B2 (https=)
BG (1) BG64889B1 (https=)
BR (1) BR0104354A (https=)
CA (1) CA2368274C (https=)
CZ (1) CZ20013430A3 (https=)
DE (1) DE60138853D1 (https=)
GE (1) GEP20043323B (https=)
HU (1) HUP0600302A2 (https=)
IL (1) IL145638A (https=)
MX (1) MXPA01009905A (https=)
NO (1) NO327910B1 (https=)
NZ (1) NZ514382A (https=)
PL (1) PL202957B1 (https=)
RO (1) RO121270B1 (https=)
RU (1) RU2262506C2 (https=)
SK (1) SK13692001A3 (https=)
TR (1) TR200102858T1 (https=)
TW (1) TWI299732B (https=)
UA (1) UA75039C2 (https=)
WO (1) WO2001057032A1 (https=)
ZA (1) ZA200108055B (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CA2354471A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 ester substituted taxanes
SG129990A1 (en) * 2001-08-01 2007-03-20 Univ Florida State Res Found C10 ester substituted taxanes
HN2005000054A (es) 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
JP2008530122A (ja) * 2005-02-14 2008-08-07 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド C10シクロプロピルエステル置換タキサン組成物
JP2011517455A (ja) * 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド C(10)エチルエステルおよびc(10)シクロプロピルエステル置換タキサン

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
IL108443A0 (en) * 1993-01-29 1994-04-12 Univ Florida State C7 taxane derivatives and pharmaceutical compositions containing them
DK0690867T3 (da) * 1993-03-22 2003-06-10 Univ Florida State Taxaner med furyl- eller thienylsubstitueret sidekæde
DE69425563T2 (de) * 1993-03-22 2001-01-25 Florida State University, Tallahassee Taxane mit amino-substituierter seitenkette
EP0690712B1 (en) * 1993-03-22 2001-11-28 Florida State University Taxanes having a pyridyl substituted side-chain
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
EP0788493A1 (en) * 1994-10-28 1997-08-13 The Research Foundation Of State University Of New York Taxoid derivatives, their preparation and their use as antitumor agents
US6100411A (en) * 1994-10-28 2000-08-08 The Research Foundation Of State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
ES2151277T3 (es) * 1996-05-22 2000-12-16 Protarga Inc Composiciones que comprenden conjugados de acido cis-docosahexaenoico y taxotere.
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
WO1999032473A1 (en) * 1997-12-19 1999-07-01 Kabushiki Kaisha Yakult Honsha Taxane derivatives
JP2003026673A (ja) * 1999-03-05 2003-01-29 Asahi Kasei Corp 骨形成促進剤

Also Published As

Publication number Publication date
UA75039C2 (en) 2006-03-15
IL145638A0 (en) 2002-06-30
BG64889B1 (bg) 2006-08-31
RO121270B1 (ro) 2007-02-28
JP2003522172A (ja) 2003-07-22
CA2368274C (en) 2009-10-13
EP1165553A1 (en) 2002-01-02
RU2262506C2 (ru) 2005-10-20
AU3480901A (en) 2001-08-14
NO20014754L (no) 2001-11-29
NO20014754D0 (no) 2001-10-01
TR200102858T1 (tr) 2002-12-23
MXPA01009905A (es) 2003-08-20
CA2368274A1 (en) 2001-08-09
NO327910B1 (no) 2009-10-19
SK13692001A3 (sk) 2002-07-02
HUP0600302A2 (en) 2006-07-28
ATE432928T1 (de) 2009-06-15
CZ20013430A3 (cs) 2002-04-17
PL202957B1 (pl) 2009-08-31
BG105965A (en) 2002-07-31
AU782150B2 (en) 2005-07-07
DE60138853D1 (de) 2009-07-16
WO2001057032A1 (en) 2001-08-09
BR0104354A (pt) 2002-01-02
PL351380A1 (en) 2003-04-07
NZ514382A (en) 2004-05-28
IL145638A (en) 2011-05-31
TWI299732B (en) 2008-08-11
EP1165553B1 (en) 2009-06-03
ZA200108055B (en) 2003-12-01
CN1380882A (zh) 2002-11-20

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