GEP19981256B - Method of producing emulsion of 9- 2-oxyethoxymethyl guanine "aciclovir" - Google Patents

Method of producing emulsion of 9- 2-oxyethoxymethyl guanine "aciclovir"

Info

Publication number
GEP19981256B
GEP19981256B GEAP19942163A GEAP1994002163A GEP19981256B GE P19981256 B GEP19981256 B GE P19981256B GE AP19942163 A GEAP19942163 A GE AP19942163A GE AP1994002163 A GEAP1994002163 A GE AP1994002163A GE P19981256 B GEP19981256 B GE P19981256B
Authority
GE
Georgia
Prior art keywords
mass
oxyethoxymethyl
guanine
aciclovir
producing emulsion
Prior art date
Application number
GEAP19942163A
Other languages
English (en)
Inventor
Trevor M Jones
Original Assignee
The Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Wellcome Foundation Ltd filed Critical The Wellcome Foundation Ltd
Publication of GEP19981256B publication Critical patent/GEP19981256B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dispersion Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
GEAP19942163A 1980-07-18 1994-09-07 Method of producing emulsion of 9- 2-oxyethoxymethyl guanine "aciclovir" GEP19981256B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8023645 1980-07-18

Publications (1)

Publication Number Publication Date
GEP19981256B true GEP19981256B (en) 1998-04-01

Family

ID=10514892

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP19942163A GEP19981256B (en) 1980-07-18 1994-09-07 Method of producing emulsion of 9- 2-oxyethoxymethyl guanine "aciclovir"

Country Status (6)

Country Link
US (1) US4963555A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0148885B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (1) KR830005852A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GE (1) GEP19981256B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (1) SU1375113A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA814925B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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GB9001886D0 (en) * 1990-01-26 1990-03-28 Beecham Group Plc Pharmaceutical formulation
GB9315755D0 (en) * 1993-07-30 1993-09-15 Wellcome Found Stabilized formulation
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US6653318B1 (en) 1999-07-21 2003-11-25 Yale University 5-(E)-Bromovinyl uracil analogues and related pyrimidine nucleosides as anti-viral agents and methods of use
US20050058673A1 (en) 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
AU2004270258A1 (en) * 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
WO2005067941A1 (es) * 2004-01-08 2005-07-28 Universidad De Concepcion Formulacion topica de aciclovir
US9028852B2 (en) 2004-09-07 2015-05-12 3M Innovative Properties Company Cationic antiseptic compositions and methods of use
US20060051384A1 (en) * 2004-09-07 2006-03-09 3M Innovative Properties Company Antiseptic compositions and methods of use
US8198326B2 (en) * 2004-09-07 2012-06-12 3M Innovative Properties Company Phenolic antiseptic compositions and methods of use
CN101137359B (zh) 2005-03-10 2011-01-12 3M创新有限公司 治疗耳感染的方法
ATE511838T1 (de) 2005-03-10 2011-06-15 3M Innovative Properties Co Antimikrobielle zusammensetzungen mit hydroxycarboxylsäureestern
CA2599653A1 (en) 2005-03-10 2006-09-21 3M Innovative Properties Company Methods of reducing microbial contamination
US8771712B2 (en) * 2006-05-09 2014-07-08 Emisphere Technologies, Inc. Topical administration of acyclovir
JP4972062B2 (ja) * 2008-03-17 2012-07-11 メディヴィル・アクチエボラーグ 抗ウイルス製剤
US8236768B2 (en) 2008-10-03 2012-08-07 3B Pharmaceuticals, Inc. Topical antiviral formulations
WO2011035120A2 (en) * 2009-09-17 2011-03-24 Gk Ventures, L.L.C. Therapeutic composition to treat lesions caused by herpes simplex virus
US8853223B2 (en) * 2010-09-17 2014-10-07 G2L Touch, Inc. Therapeutic composition to treat lesions caused by herpes simplex virus
RU2457843C1 (ru) * 2011-05-11 2012-08-10 Общество с ограниченной ответственностью фирма "Вита" Стабилизированный фармацевтический состав с противовирусным действием
CA2856696C (en) * 2011-11-23 2020-07-14 3B Pharmaceuticals, Inc. Antiviral formulations for herpes viral infections
US10456435B2 (en) 2015-07-15 2019-10-29 Christopher A. MCELVANY Topical antiviral formulations and methods of using the same
WO2018231863A1 (en) * 2017-06-12 2018-12-20 Lakewood Amedex, Inc Bisphosphocin gel formulations and uses thereof
US11246872B2 (en) 2019-06-14 2022-02-15 Propella Therapeutics, Inc. Topical acyclovir formulations and uses thereof

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US3536816A (en) * 1964-09-30 1970-10-27 Atlas Chem Ind Water-in-oil emulsion
US3592930A (en) * 1968-07-19 1971-07-13 Syntex Corp Moisture-deterioratable topical medicaments,particularly anti-inflammatory steroids,in a substantially non-aqueous fatty alcohol-propylene glycol vehicle
CH528266A (fr) * 1969-11-26 1972-09-30 Orsymonde Procédé pour la préparation d'une composition lyophilisée à l'usage cosmétique ou hygiénique
US3924004A (en) * 1971-11-24 1975-12-02 Syntex Corp Fatty alcohol-propylene carbonate-glycol solvent cream vehicle
ZA72698B (en) * 1972-02-03 1973-09-26 Liebenberg R W Method of preparing medicinal compositions
US3892857A (en) * 1972-11-24 1975-07-01 Squibb & Sons Inc Steroid formulation
ZA738657B (en) * 1973-01-05 1974-10-30 Hoffmann La Roche Emulsions
GB1478009A (en) * 1973-04-02 1977-06-29 Glaxo Lab Ltd Pharmaceutical compositions
US3867528A (en) * 1973-10-11 1975-02-18 American Cyanamid Co Steroidal topical cream base
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
GB1543907A (en) * 1975-02-19 1979-04-11 Dermal Labor Ltd Steroid compositions
US3934013A (en) * 1975-02-21 1976-01-20 Syntex (U.S.A.) Inc. Pharmaceutical composition
US4049802A (en) * 1975-03-19 1977-09-20 Research Corporation Zinc sulfadiazine and its use in the treatment of burns
GB1554720A (en) * 1975-07-10 1979-10-24 Nyegaard & Co As Pyridthione derivatives
US4141976A (en) * 1976-01-05 1979-02-27 The Regents Of The University Of Michigan Process for alleviating proliferative skin diseases
JPS52105195A (en) * 1976-03-01 1977-09-03 Wellcome Found Substituted purine
SE7702990L (sv) * 1976-03-19 1977-09-20 Minnesota Mining & Mfg Tropiskt administreringssystem for lekemedel med forsterkt peutreringsformaga
DE2646435B2 (de) * 1976-10-14 1979-05-31 Shiseido Co., Ltd., Tokio Verfahren zur Herstellung einer stabilen Öl-in-Wasser-Emulsion
GB1556632A (en) * 1977-01-14 1979-11-28 Sterling Drug Inc Antimicrobial skin cleasing composition
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
CA1113005A (en) * 1977-12-06 1981-11-24 Pierluigi Vanoni Excipient composition for creams
DE2847975A1 (de) * 1978-11-04 1980-05-14 Merck Patent Gmbh Verfahren zur bindung von freiem formaldehyd in pharmazeutischen und kosmetischen zubereitungen

Also Published As

Publication number Publication date
SU1375113A3 (ru) 1988-02-15
JPH0148885B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1989-10-20
KR830005852A (ko) 1983-09-14
US4963555A (en) 1990-10-16
ZA814925B (en) 1983-02-23
JPS5742615A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-03-10

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