GB999590A - ª‡-substituted carboxylic acid derivatives and their production - Google Patents

ª‡-substituted carboxylic acid derivatives and their production

Info

Publication number
GB999590A
GB999590A GB786062A GB786062A GB999590A GB 999590 A GB999590 A GB 999590A GB 786062 A GB786062 A GB 786062A GB 786062 A GB786062 A GB 786062A GB 999590 A GB999590 A GB 999590A
Authority
GB
United Kingdom
Prior art keywords
production
carboxylic acid
acid derivatives
substituted carboxylic
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB786062A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
LIPHA Liyonnaise Industrielle Pharmaceutique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR853462A external-priority patent/FR1289561A/en
Application filed by LIPHA SAS, LIPHA Liyonnaise Industrielle Pharmaceutique filed Critical LIPHA SAS
Publication of GB999590A publication Critical patent/GB999590A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Abstract

The invention comprises compounds of general formula <FORM:0999590/C2/1> where m is 0 or 1, n is 1 or 3, R1 is CN or CONH2, and R2 is a furyl or tetrahydrofuryl radical or, when m is 0 and n is 1, a vinyl or 1propenyl radical; and their preparation by reacting a compound of formula Naphthyl-(CH2)m-CH2-CN or R2-(CH2)n-CH2-CN with an alkali metal condensing agent and condensing the resulting alkali metal derivative with a compound R2-(CH2)n-X or Naphthyl-(CH2)m-X respectively (where X is halogen), so forming the above nitriles which may then be hydrolysed with a substantially equimolar quantity of an alkali in the presence of an alcohol to yield the amides.
GB786062A 1961-02-23 1962-02-16 ª‡-substituted carboxylic acid derivatives and their production Expired GB999590A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR853462A FR1289561A (en) 1961-02-21 1961-02-23 Device for applying liquid active products by massage

Publications (1)

Publication Number Publication Date
GB999590A true GB999590A (en) 1965-07-28

Family

ID=8749371

Family Applications (1)

Application Number Title Priority Date Filing Date
GB786062A Expired GB999590A (en) 1961-02-23 1962-02-16 ª‡-substituted carboxylic acid derivatives and their production

Country Status (1)

Country Link
GB (1) GB999590A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008532A1 (en) * 1978-08-22 1980-03-05 Sumitomo Chemical Company, Limited Synthesis of amines

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008532A1 (en) * 1978-08-22 1980-03-05 Sumitomo Chemical Company, Limited Synthesis of amines
EP0040896A2 (en) * 1978-08-22 1981-12-02 Sumitomo Chemical Company, Limited Synthesis of amides
EP0040896A3 (en) * 1978-08-22 1982-02-03 Sumitomo Chemical Company, Limited Synthesis of amides

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