GB990275A - Hardening of proteinaceous materials - Google Patents

Abstract

N,N1 - bis - (bromoacetyl)ethylenediamine and N,N1 - bis(bromoacetyl)propylene - diamine-1,3 can be prepared by reacting bromoacetyl bromide with ethylene diamine or trimethylene diamine respectively. N,N1 - bis(bromoacetyl) - hydrazine may be prepared by reacting bromoacetic anhydride with hydrazine carboxylic acid. N,N1 - bis(bromoacetyl) - dimethylhydrazine may be prepared by reacting dimethylhydrazine with bromoacetyl chloride. Specifications 822,061, 860,631, 860,632, 891,221 and 932,978 are referred to.ALSO:Proteinaceous materials, particularly gelatin, may be hardened by reaction with one or more compounds according to the general formula <FORM:0990275/C3/1> wherein each of X and X1 (the same or different) represents a halogen atom, each of R1, R2, R3 and R4 (the same or two or more of them different) represents a hydrogen atom or an alkyl group, and A represents an arylene radical, a -CO-NH-CO-NH-CO- group, a -CO-NH-CO-CO-NH-CO- group, a -CO-NH-CO- alkylene -CO-NH-CO- group, a -CO-NH-CO- arylene -CO-NH-CO- group, a -CO-NH-SO2- alkylene -SO2-NH-CO- group, a -CO-NH-SO2- arylene -SO2-NH-CO- group, a -CO-NH-CO- group, a -CO-N (alkyl)-CO- group, a -CO-NH-NH-CO- group, a -CO-N (alkyl)-N (alkyl)-CO- group, a -CO-NH-alkylene-NH-CO- group, a -CO-N (alkyl) - alkylene-N (alkyl)-CO- group, a -CO-NH-arylene-NH-CO- group, or a -CO-N (alkyl) - arylene - N (alkyl)-CO- group. The subject-matter of Specification 932,978 is disclaimed. Hardeners referred to in the Specification are bis-chloroacetylamine, N,N1-bis-(chloroacetyl) - urea, N,N1 - bis - (a - bromopropionyl) - ethylenediamine, N,N1 - dibromoacetylethylenediamine, N,N1 - dibromoacetylpropylenediamine-1,3, N,N1 - bis - (bromoacetyl) hydrazine and N,N1 - bis - (bromoacetyl) dimethylhydrazine. Specifications 822,061, 860,631, 860,632 and 891,221 are referred to.