GB986209A - Cephalosporin compounds - Google Patents
Cephalosporin compoundsInfo
- Publication number
- GB986209A GB986209A GB32223/62A GB3222362A GB986209A GB 986209 A GB986209 A GB 986209A GB 32223/62 A GB32223/62 A GB 32223/62A GB 3222362 A GB3222362 A GB 3222362A GB 986209 A GB986209 A GB 986209A
- Authority
- GB
- United Kingdom
- Prior art keywords
- naphthamido
- acyloxy
- tertiary
- amino
- cephalosporin compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
Abstract
Cephalosporins of the formula <FORM:0986209/C2/1> wherein R1, taken alone, is -OH, C1-C8 acyloxy, or tertiary-amino; R2 is -OH when R1 is -OH; R2 is -OH when R1 is C1-C8 acyloxy R2 is -O- when R1 is tertiary-amino; R1 and R2, when taken together, are -O-; R is cyclobutyl, cyclopentyl, naphthyl, or adamantyl or a substitution product thereof having at least one substituent consisting of halogen, nitrotrifluoromethyl, C1-C4 alkyl or C1-C2 alkoxy, and the pharmaceutically acceptable salts, esters and amides thereof may be produced by acylating the relevant cephalosporin nucleus with an appropriate acylating agent. Examples describe the production of 7-a -naphthamido-, 7-b -naphthamido- and 7-adamantane-cephalosporanic acids. Specifications 810,196, 912,360 and 912,541 are referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US133338A US3216999A (en) | 1961-08-23 | 1961-08-23 | Carbocyclic cephalosporins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB986209A true GB986209A (en) | 1965-03-17 |
Family
ID=22458116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB32223/62A Expired GB986209A (en) | 1961-08-23 | 1962-08-22 | Cephalosporin compounds |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US3216999A (en) |
| BR (1) | BR6242365D0 (en) |
| FR (1) | FR1605105A (en) |
| GB (1) | GB986209A (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1104938A (en) * | 1964-05-28 | 1968-03-06 | Glaxo Lab Ltd | Improvements in or relating to 7-aminocephalosporanic acid |
| GB1195203A (en) * | 1966-06-24 | 1970-06-17 | Glaxo Lab Ltd | Cephalosporins |
| AU552746B2 (en) * | 1981-09-22 | 1986-06-19 | Kureha Kagaku Kogyo K.K. | Cephalosporin derivative |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE593777A (en) * | ||||
| US2941995A (en) * | 1957-08-02 | 1960-06-21 | Beecham Res Lab | Recovery of solid 6-aminopenicillanic acid |
-
1961
- 1961-08-23 US US133338A patent/US3216999A/en not_active Expired - Lifetime
-
1962
- 1962-08-22 GB GB32223/62A patent/GB986209A/en not_active Expired
- 1962-08-23 FR FR1605105D patent/FR1605105A/en not_active Expired
- 1962-08-23 BR BR142365/62A patent/BR6242365D0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR1605105A (en) | 1973-03-16 |
| BR6242365D0 (en) | 1973-07-12 |
| US3216999A (en) | 1965-11-09 |
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