FR1605105A - Modified cephalosporin c-type antibiotics - Google Patents
Modified cephalosporin c-type antibioticsInfo
- Publication number
- FR1605105A FR1605105A FR1605105DA FR1605105A FR 1605105 A FR1605105 A FR 1605105A FR 1605105D A FR1605105D A FR 1605105DA FR 1605105 A FR1605105 A FR 1605105A
- Authority
- FR
- France
- Prior art keywords
- cephalosporin
- agst
- acyloxy
- tert
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Cephalosporin C-type cpds. of the general formula:- where R1 = HO, (1-8C)acyloxy, tert. amino R2 = HO (when R1 = HO, acyloxy) or O- (when R1 = tert. amino) or R1+R2= -O- R = cyclo(butyl, pentyl), naphthyl, adamantyl; these may be substd. by: halogen, NO2, CF3, (1-4C)alkyl, (1-2C)alkoxy, together with pharm. accept. salts, esters and amides thereof. 7-Acylamino derivs. of cephalosporanic acid:- alpha- and beta-naphthoyl adamantane-CO Active agst. Staph. albus, B.subtilis, Sarcina lutea. Also agst. resistant Staph.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US133338A US3216999A (en) | 1961-08-23 | 1961-08-23 | Carbocyclic cephalosporins |
Publications (1)
Publication Number | Publication Date |
---|---|
FR1605105A true FR1605105A (en) | 1973-03-16 |
Family
ID=22458116
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR1605105D Expired FR1605105A (en) | 1961-08-23 | 1962-08-23 | Modified cephalosporin c-type antibiotics |
Country Status (4)
Country | Link |
---|---|
US (1) | US3216999A (en) |
BR (1) | BR6242365D0 (en) |
FR (1) | FR1605105A (en) |
GB (1) | GB986209A (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1104938A (en) * | 1964-05-28 | 1968-03-06 | Glaxo Lab Ltd | Improvements in or relating to 7-aminocephalosporanic acid |
GB1195203A (en) * | 1966-06-24 | 1970-06-17 | Glaxo Lab Ltd | Cephalosporins |
AU552746B2 (en) * | 1981-09-22 | 1986-06-19 | Kureha Kagaku Kogyo K.K. | Cephalosporin derivative |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE593777A (en) * | ||||
US2941995A (en) * | 1957-08-02 | 1960-06-21 | Beecham Res Lab | Recovery of solid 6-aminopenicillanic acid |
-
1961
- 1961-08-23 US US133338A patent/US3216999A/en not_active Expired - Lifetime
-
1962
- 1962-08-22 GB GB32223/62A patent/GB986209A/en not_active Expired
- 1962-08-23 BR BR142365/62A patent/BR6242365D0/en unknown
- 1962-08-23 FR FR1605105D patent/FR1605105A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
US3216999A (en) | 1965-11-09 |
GB986209A (en) | 1965-03-17 |
BR6242365D0 (en) | 1973-07-12 |
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