GB985482A - 2-methylene testosterone derivatives and methods for producing the same - Google Patents
2-methylene testosterone derivatives and methods for producing the sameInfo
- Publication number
- GB985482A GB985482A GB161761A GB161761A GB985482A GB 985482 A GB985482 A GB 985482A GB 161761 A GB161761 A GB 161761A GB 161761 A GB161761 A GB 161761A GB 985482 A GB985482 A GB 985482A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroids
- general formula
- hydroxymethylene
- above significance
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Abstract
The invention comprises steroids of the general formula <FORM:0985482/C2/1> wherein Y represents hydrogen or the methyl group and Z represents a hydroxymethylene, alkanoyloxymethylene, alkyl substituted hydroxymethylene (C(a -alkyl)OH), carbonyl or ethynyl substituted hydroxymethylene (C(a -CCH)OH) group, and a process for the preparation of steroids of the general formula <FORM:0985482/C2/2> wherein Y and R have the above significance, by treating 2-alkoxyoxalyl-steroids of the general formula <FORM:0985482/C2/3> wherein Y and R have the above significance, with formaldehyde in the presence of a basic catalyst, a process for the production of steroids of the general formula <FORM:0985482/C2/4> wherein Y has the above significance, by acylating the corresponding 17b -hydroxy-steroid, and a process for the preparation of steroids of the general formula <FORM:0985482/C2/5> wherein Y has the above significance, by oxidizing the corresponding 17b -hydroxy compound. The alkyl groups contain 1 to 3 carbon atoms and the alkanoyloxy groups contain not more than 4 carbon atoms. Therapeutic compositions suitable for oral or parenteral administration having anabolic activity contain as the active ingredient a steroid of the first general formula above. 2-Alkoxyoxalyl-steroids of the third general formula above are prepared by treating the corresponding steroids unsubstituted at the 2-position with an excess of dialkyl oxalate.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB161761A GB985482A (en) | 1961-01-13 | 1961-01-13 | 2-methylene testosterone derivatives and methods for producing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB161761A GB985482A (en) | 1961-01-13 | 1961-01-13 | 2-methylene testosterone derivatives and methods for producing the same |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB985482A true GB985482A (en) | 1965-03-10 |
Family
ID=9725044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB161761A Expired GB985482A (en) | 1961-01-13 | 1961-01-13 | 2-methylene testosterone derivatives and methods for producing the same |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB985482A (en) |
-
1961
- 1961-01-13 GB GB161761A patent/GB985482A/en not_active Expired
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB1152226A (en) | Novel Gona-1,3,5(10)-Trienes, processes for their preparation, and compositions incorporating them | |
| ES436043A1 (en) | 16-Oxygenated prostanoic acid derivatives | |
| GB1040545A (en) | Improvements in or relating to therapeutic compounds and the manufacture thereof | |
| GB1399162A (en) | 6-keto-delta1,3,5-10-steroids and process for the manufacture of 6-keto-delta1,3,5-10-steroids | |
| GB1104462A (en) | 7ª-methyl-steroids of the oestrane series | |
| ES424851A1 (en) | A procedure for preparing piperazine derivatives. (Machine-translation by Google Translate, not legally binding) | |
| GB1081647A (en) | Furan compounds | |
| GB985482A (en) | 2-methylene testosterone derivatives and methods for producing the same | |
| GB1112840A (en) | Steroids having pro-oestrogenic activity | |
| GB1110759A (en) | Oestrogenically active steroids and a process for their manufacture | |
| ES288360A1 (en) | A procedure for preparing a gonadienone (Machine-translation by Google Translate, not legally binding) | |
| GB1117456A (en) | 1ªß-methyl-2,3ª-methylene steroids and a process for their manufacture | |
| GB1100444A (en) | 13-alkyl 17-halogenoalkynyl steroid 3-alcohols and their esters | |
| GB1108664A (en) | 13-alkyl-gonatriene derivatives | |
| GB1018780A (en) | Steroid (2,3í¬c) furazan compounds and the process for the production thereof | |
| GB1041278A (en) | 13-alkyl steroid ketone derivatives | |
| ES364980A1 (en) | A method for preparing new adamantan derivatives. (Machine-translation by Google Translate, not legally binding) | |
| GB950899A (en) | Improvements in or relating to steroidal alkyl ethers | |
| GB1191347A (en) | 03-Alkyl-10-Methylgon-4-En-3-Ones and their Derivatives | |
| GB980016A (en) | ||
| GB928714A (en) | Process for the preparation of 4-hydroxy-3-keto-í¸-steroids | |
| ES436627A1 (en) | Procedure for the preparation of chromenum derivatives. (Machine-translation by Google Translate, not legally binding) | |
| GB1073309A (en) | 18-nor-steroids | |
| GB1345388A (en) | 2,3-ketalised-rhamnopyranosides and process for preparing them | |
| GB1023719A (en) | Substituted 19-norandrosta-5(10),9(11)-dienes and method of preparing same |