GB9808327D0 - Antidiotypic compounds - Google Patents
Antidiotypic compoundsInfo
- Publication number
- GB9808327D0 GB9808327D0 GBGB9808327.2A GB9808327A GB9808327D0 GB 9808327 D0 GB9808327 D0 GB 9808327D0 GB 9808327 A GB9808327 A GB 9808327A GB 9808327 D0 GB9808327 D0 GB 9808327D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- antidiotypic
- gbs
- oligopeptide
- eliciting
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 241000193990 Streptococcus sp. 'group B' Species 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000015636 Oligopeptides Human genes 0.000 abstract 1
- 108010038807 Oligopeptides Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 244000052769 pathogen Species 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
- C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
- C07K16/4233—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-bacterial Ig
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (11)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9808327.2A GB9808327D0 (en) | 1998-04-20 | 1998-04-20 | Antidiotypic compounds |
| AT99914725T ATE425251T1 (de) | 1998-04-20 | 1999-04-20 | Impfstoffe welche antiidiotypische antikörper enthalten, die kohlenhydrate von streptococcus gruppe b nachahmen |
| DE69940545T DE69940545D1 (de) | 1998-04-20 | 1999-04-20 | Impfstoffe welche antiidiotypische antikörper enthalten, die kohlenhydrate von streptococcus gruppe b nachahmen |
| US09/673,867 US6676938B1 (en) | 1998-04-20 | 1999-04-20 | Vaccine formulations comprising antiidiotypic antibodies which immunologically mimic group B streptococcal carbohydrates |
| PCT/IB1999/000799 WO1999054457A1 (en) | 1998-04-20 | 1999-04-20 | Vaccine formulations comprising antiidiotypic antibodies which immunologically mimic group b streptococcal carbohydrates |
| CA2325566A CA2325566C (en) | 1998-04-20 | 1999-04-20 | Vaccine formulations comprising antiidiotypic antibodies which immunologically mimic group b streptococcal carbohydrates |
| EP99914725A EP1071763B1 (en) | 1998-04-20 | 1999-04-20 | Vaccine formulations comprising antiidiotypic antibodies which immunologically mimic group b streptococcal carbohydrates |
| JP2000544789A JP4446601B2 (ja) | 1998-04-20 | 1999-04-20 | B群連鎖球菌の糖質を免疫学的に模倣する抗イディオタイプ抗体を含むワクチン処方物 |
| US10/703,886 US6900302B2 (en) | 1998-04-20 | 2003-11-07 | Vaccine formulations comprising antiidiotypic antibodies which immunologically mimic group B streptococcal carbohydrates |
| JP2009123637A JP2009179645A (ja) | 1998-04-20 | 2009-05-21 | B群連鎖球菌の糖質を免疫学的に模倣する抗イディオタイプ抗体を含むワクチン処方物 |
| CY20091100604T CY1109140T1 (el) | 1998-04-20 | 2009-06-09 | Τυποποιησεις εμβολιων που περιλαμβανουν αντιιδιοτυπικα αντισωματα τα οποια μιμουνται ανοσολογικα υαδατανθρακες των στρεπτοκοκκων ομαδας β |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9808327.2A GB9808327D0 (en) | 1998-04-20 | 1998-04-20 | Antidiotypic compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB9808327D0 true GB9808327D0 (en) | 1998-06-17 |
Family
ID=10830608
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB9808327.2A Ceased GB9808327D0 (en) | 1998-04-20 | 1998-04-20 | Antidiotypic compounds |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6676938B1 (enExample) |
| EP (1) | EP1071763B1 (enExample) |
| JP (2) | JP4446601B2 (enExample) |
| AT (1) | ATE425251T1 (enExample) |
| CA (1) | CA2325566C (enExample) |
| CY (1) | CY1109140T1 (enExample) |
| DE (1) | DE69940545D1 (enExample) |
| GB (1) | GB9808327D0 (enExample) |
| WO (1) | WO1999054457A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10027695A1 (de) * | 1999-05-27 | 2001-04-19 | Max Delbrueck Centrum | Vakzine gegen konformationsabhängige Antigene sowie gegen Antigene, die keine oder nicht ausschließlich Proteine oder Peptide sind |
| ES2330083T3 (es) * | 2000-10-27 | 2009-12-04 | Novartis Vaccines And Diagnostics S.R.L. | Acidos nucleicos y proteinas de estreptococos de los grupos a y b. |
| AU2003260102A1 (en) * | 2002-08-26 | 2004-03-11 | Chiron Corporation | Conserved and specific streptococcal genomes |
| ES2505695T3 (es) | 2003-07-31 | 2014-10-10 | Novartis Vaccines And Diagnostics, Inc. | Composiciones inmunógenas para Streptococcus pyogenes |
| US8945589B2 (en) | 2003-09-15 | 2015-02-03 | Novartis Vaccines And Diagnostics, Srl | Immunogenic compositions for Streptococcus agalactiae |
| CA2575548A1 (en) | 2004-07-29 | 2006-07-27 | John L. Telford | Immunogenic compositions for gram positive bacteria such as streptococcus agalactiae |
| EP1807446A2 (en) * | 2004-10-08 | 2007-07-18 | Novartis Vaccines and Diagnostics, Inc. | Immunogenic and therapeutic compositions for streptococcus pyogenes |
| US20090104218A1 (en) * | 2004-12-22 | 2009-04-23 | J. Craig Venter Institute | Group B Streptococcus |
| EP2298795A1 (en) | 2005-02-18 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Immunogens from uropathogenic escherichia coli |
| PT2054431E (pt) * | 2006-06-09 | 2011-11-03 | Novartis Ag | Confórmeros de adesinas bacterianas |
| JP2010500399A (ja) | 2006-08-16 | 2010-01-07 | ノバルティス アーゲー | 尿路病原性大腸菌由来の免疫原 |
| WO2008108830A2 (en) * | 2006-10-30 | 2008-09-12 | Novartis Ag | Immunogenic and therapeutic compositions for streptococcus pyogenes |
| JP5653215B2 (ja) | 2007-09-12 | 2015-01-14 | ノバルティス アーゲー | Gas57変異体抗原およびgas57抗体 |
| EP2537857B1 (en) * | 2007-12-21 | 2017-01-18 | GlaxoSmithKline Biologicals SA | Mutant forms of streptolysin O |
| EP3578205A1 (en) | 2010-08-06 | 2019-12-11 | ModernaTX, Inc. | A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof |
| CN103429606A (zh) | 2010-10-01 | 2013-12-04 | 现代治疗公司 | 设计核酸及其使用方法 |
| CA2831613A1 (en) | 2011-03-31 | 2012-10-04 | Moderna Therapeutics, Inc. | Delivery and formulation of engineered nucleic acids |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| KR20190099538A (ko) | 2011-10-03 | 2019-08-27 | 모더나 세라퓨틱스, 인코포레이티드 | 변형된 뉴클레오사이드, 뉴클레오타이드, 및 핵산, 및 이들의 용도 |
| EP4144378A1 (en) | 2011-12-16 | 2023-03-08 | ModernaTX, Inc. | Modified nucleoside, nucleotide, and nucleic acid compositions |
| AU2013243954A1 (en) | 2012-04-02 | 2014-10-30 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| US9254311B2 (en) | 2012-04-02 | 2016-02-09 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of proteins |
| DK2922554T3 (en) | 2012-11-26 | 2022-05-23 | Modernatx Inc | Terminalt modificeret rna |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| US10023626B2 (en) | 2013-09-30 | 2018-07-17 | Modernatx, Inc. | Polynucleotides encoding immune modulating polypeptides |
| BR112016007255A2 (pt) | 2013-10-03 | 2017-09-12 | Moderna Therapeutics Inc | polinucleotídeos que codificam receptor de lipoproteína de baixa densidade |
| EP3773348B1 (en) | 2018-04-10 | 2025-04-02 | Alps Holding Llc | Spinal interbody cage comprising top and bottom faces with mesh structures, pillars and slots |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5476784A (en) * | 1993-04-06 | 1995-12-19 | Rice; Peter A. | Gonococcal anti-idiotypic antibodies and methods and compositions using them |
| WO1997045449A1 (en) * | 1996-05-29 | 1997-12-04 | Derek Nigel John Hart | Dendritic cell receptor |
| US6140091A (en) * | 1997-06-20 | 2000-10-31 | Boston Biomedical Research Institute | Anti-idiotype vaccines to elicit catalytic antibodies |
| US6444787B1 (en) * | 1997-12-31 | 2002-09-03 | Research Development Institute, Inc. | Method of isolating a peptide which immunologically mimics microbial carbohydrates including group B streptococcal carbohydrates and the use thereof in a vaccine |
-
1998
- 1998-04-20 GB GBGB9808327.2A patent/GB9808327D0/en not_active Ceased
-
1999
- 1999-04-20 AT AT99914725T patent/ATE425251T1/de active
- 1999-04-20 CA CA2325566A patent/CA2325566C/en not_active Expired - Fee Related
- 1999-04-20 WO PCT/IB1999/000799 patent/WO1999054457A1/en not_active Ceased
- 1999-04-20 EP EP99914725A patent/EP1071763B1/en not_active Expired - Lifetime
- 1999-04-20 DE DE69940545T patent/DE69940545D1/de not_active Expired - Lifetime
- 1999-04-20 US US09/673,867 patent/US6676938B1/en not_active Expired - Fee Related
- 1999-04-20 JP JP2000544789A patent/JP4446601B2/ja not_active Expired - Fee Related
-
2003
- 2003-11-07 US US10/703,886 patent/US6900302B2/en not_active Expired - Fee Related
-
2009
- 2009-05-21 JP JP2009123637A patent/JP2009179645A/ja not_active Withdrawn
- 2009-06-09 CY CY20091100604T patent/CY1109140T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1071763B1 (en) | 2009-03-11 |
| CY1109140T1 (el) | 2014-07-02 |
| JP2002512026A (ja) | 2002-04-23 |
| ATE425251T1 (de) | 2009-03-15 |
| CA2325566C (en) | 2011-02-08 |
| EP1071763A1 (en) | 2001-01-31 |
| DE69940545D1 (de) | 2009-04-23 |
| JP2009179645A (ja) | 2009-08-13 |
| WO1999054457A1 (en) | 1999-10-28 |
| US20040101536A1 (en) | 2004-05-27 |
| US6900302B2 (en) | 2005-05-31 |
| US6676938B1 (en) | 2004-01-13 |
| JP4446601B2 (ja) | 2010-04-07 |
| CA2325566A1 (en) | 1999-10-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |