GB929252A - New 1-(trialkoxy benzyl)-piperazines - Google Patents

New 1-(trialkoxy benzyl)-piperazines

Info

Publication number
GB929252A
GB929252A GB1748061A GB1748061A GB929252A GB 929252 A GB929252 A GB 929252A GB 1748061 A GB1748061 A GB 1748061A GB 1748061 A GB1748061 A GB 1748061A GB 929252 A GB929252 A GB 929252A
Authority
GB
United Kingdom
Prior art keywords
piperazine
chloride
compounds
hydrolysing
reacting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1748061A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of GB929252A publication Critical patent/GB929252A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
GB1748061A 1960-06-30 1961-06-02 New 1-(trialkoxy benzyl)-piperazines Expired GB929252A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR831847A FR805M (fr) 1960-06-30 1960-06-30

Publications (1)

Publication Number Publication Date
GB929252A true GB929252A (en) 1963-06-19

Family

ID=8734718

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1748061A Expired GB929252A (en) 1960-06-30 1961-06-02 New 1-(trialkoxy benzyl)-piperazines

Country Status (5)

Country Link
BE (1) BE604839A (fr)
CH (1) CH406224A (fr)
ES (1) ES268523A1 (fr)
FR (1) FR805M (fr)
GB (1) GB929252A (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187639A1 (fr) * 1985-01-11 1986-07-16 Kanebo, Ltd. Dérivés de pipérazine, procédés pour leur production et compositions pharmaceutiques contenant ces composés comme ingrédients actifs
EP0453365A1 (fr) * 1990-04-20 1991-10-23 Adir Et Compagnie Procédé de préparation de la 1-(2,3,4-triméthoxybenzyl) pipérazine par amination réductive
EP1195160A1 (fr) * 2000-10-05 2002-04-10 USV Ltd. Composition pharmaceutique à effet de retard contenant de la trimétazidine et procédé pour sa préparation
CN100413854C (zh) * 2004-06-29 2008-08-27 北京德众万全药物技术开发有限公司 一种曲美他嗪及其药用盐的制备方法

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2490963B1 (fr) * 1980-09-30 1986-04-18 Science Union & Cie Nouvelle composition therapeutique a action anti-ischemique contenant de la trimethoxy 2, 3, 4-benzyl 1-piperazine
FR2703048B1 (fr) * 1993-03-24 1996-01-05 Adir Nouveaux composes n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2723944B1 (fr) * 1994-08-25 1996-09-20 Adir Nouveaux sels de trimetazidine et leur utilisation en therapeutique
FR2757164B1 (fr) * 1996-12-16 1999-01-22 Adir Nouveaux derives de n-benzylpiperazine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2805463B1 (fr) * 2000-02-25 2003-01-24 Adir UTILISATION DE LA TRIMETAZIDINE POUR L'OBTENTION DE COMPOSITIONS PHARMACEUTIQUES DESTINEES A INHIBER L'ACYL-CoA ACETYLTRANSFERASE

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0187639A1 (fr) * 1985-01-11 1986-07-16 Kanebo, Ltd. Dérivés de pipérazine, procédés pour leur production et compositions pharmaceutiques contenant ces composés comme ingrédients actifs
EP0453365A1 (fr) * 1990-04-20 1991-10-23 Adir Et Compagnie Procédé de préparation de la 1-(2,3,4-triméthoxybenzyl) pipérazine par amination réductive
FR2661176A1 (fr) * 1990-04-20 1991-10-25 Adir Nouveau procede de preparation de la 1-(2,3,4-trimethoxybenzyl) piperazine en amination reductive.
EP1195160A1 (fr) * 2000-10-05 2002-04-10 USV Ltd. Composition pharmaceutique à effet de retard contenant de la trimétazidine et procédé pour sa préparation
CN100413854C (zh) * 2004-06-29 2008-08-27 北京德众万全药物技术开发有限公司 一种曲美他嗪及其药用盐的制备方法

Also Published As

Publication number Publication date
FR805M (fr) 1961-09-01
DE1445138A1 (de) 1969-02-20
BE604839A (fr) 1961-10-02
CH406224A (fr) 1966-01-31
ES268523A1 (es) 1961-10-16

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