GB921045A - Production of rifamycin b - Google Patents
Production of rifamycin bInfo
- Publication number
- GB921045A GB921045A GB24882/59A GB2488259A GB921045A GB 921045 A GB921045 A GB 921045A GB 24882/59 A GB24882/59 A GB 24882/59A GB 2488259 A GB2488259 A GB 2488259A GB 921045 A GB921045 A GB 921045A
- Authority
- GB
- United Kingdom
- Prior art keywords
- rifamycin
- barbituric acid
- source
- production
- phenylethylbarbiturate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229930189077 Rifamycin Natural products 0.000 title abstract 2
- 229960003292 rifamycin Drugs 0.000 title abstract 2
- HJYYPODYNSCCOU-ODRIEIDWSA-N rifamycin SV Chemical compound OC1=C(C(O)=C2C)C3=C(O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O HJYYPODYNSCCOU-ODRIEIDWSA-N 0.000 title abstract 2
- -1 carbocyclic aryl radical Chemical class 0.000 abstract 2
- FTOAOBMCPZCFFF-UHFFFAOYSA-N 5,5-diethylbarbituric acid Chemical compound CCC1(CC)C(=O)NC(=O)NC1=O FTOAOBMCPZCFFF-UHFFFAOYSA-N 0.000 abstract 1
- RCFRTWDBBMGLGK-UHFFFAOYSA-N 5-ethyl-5-methyl-1,3-diazinane-2,4,6-trione Chemical compound CCC1(C)C(=O)NC(=O)NC1=O RCFRTWDBBMGLGK-UHFFFAOYSA-N 0.000 abstract 1
- 241001468213 Amycolatopsis mediterranei Species 0.000 abstract 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Chemical group 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- HNYOPLTXPVRDBG-UHFFFAOYSA-N barbituric acid Chemical compound O=C1CC(=O)NC(=O)N1 HNYOPLTXPVRDBG-UHFFFAOYSA-N 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 125000000118 dimethyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 229910052500 inorganic mineral Inorganic materials 0.000 abstract 1
- 239000011707 mineral Substances 0.000 abstract 1
- 235000015097 nutrients Nutrition 0.000 abstract 1
- 125000001477 organic nitrogen group Chemical group 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- DDBREPKUVSBGFI-UHFFFAOYSA-N phenobarbital Chemical compound C=1C=CC=CC=1C1(CC)C(=O)NC(=O)NC1=O DDBREPKUVSBGFI-UHFFFAOYSA-N 0.000 abstract 1
- 125000000286 phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- SQTCRTQCPJICLD-KTQDUKAHSA-N rifamycin B Chemical compound OC1=C(C(O)=C2C)C3=C(OCC(O)=O)C=C1NC(=O)\C(C)=C/C=C/[C@H](C)[C@H](O)[C@@H](C)[C@@H](O)[C@@H](C)[C@H](OC(C)=O)[C@H](C)[C@@H](OC)\C=C\O[C@@]1(C)OC2=C3C1=O SQTCRTQCPJICLD-KTQDUKAHSA-N 0.000 abstract 1
- SQTCRTQCPJICLD-OQQFTUDCSA-N rifomycin-B Natural products COC1C=COC2(C)Oc3c(C)c(O)c4c(O)c(NC(=O)C(=C/C=C/C(C)C(O)C(C)C(O)C(C)C(OC(=O)C)C1C)C)cc(OCC(=O)O)c4c3C2=O SQTCRTQCPJICLD-OQQFTUDCSA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- MHQHHBYRYFICDV-UHFFFAOYSA-M sodium;pyrimidin-3-ide-2,4,6-trione Chemical compound [Na+].O=C1CC(=O)[N-]C(=O)N1 MHQHHBYRYFICDV-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/188—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms
- C12P17/189—Heterocyclic compound containing in the condensed system at least one hetero ring having nitrogen atoms and oxygen atoms as the only ring heteroatoms containing the rifamycin nucleus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB24882/59A GB921045A (en) | 1959-07-20 | 1959-07-20 | Production of rifamycin b |
| CH740360A CH398884A (de) | 1959-07-20 | 1960-06-30 | Verfahren zur Herstellung von Rifamycin |
| BE592849A BE592849A (fr) | 1959-07-20 | 1960-07-11 | Production de rifomycine. |
| ES0259611A ES259611A1 (es) | 1959-07-20 | 1960-07-12 | Procedimiento para producir rifomicina b |
| SE700060A SE213190C1 (enrdf_load_stackoverflow) | 1959-07-20 | 1960-07-18 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB24882/59A GB921045A (en) | 1959-07-20 | 1959-07-20 | Production of rifamycin b |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB921045A true GB921045A (en) | 1963-03-13 |
Family
ID=10218742
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB24882/59A Expired GB921045A (en) | 1959-07-20 | 1959-07-20 | Production of rifamycin b |
Country Status (5)
| Country | Link |
|---|---|
| BE (1) | BE592849A (enrdf_load_stackoverflow) |
| CH (1) | CH398884A (enrdf_load_stackoverflow) |
| ES (1) | ES259611A1 (enrdf_load_stackoverflow) |
| GB (1) | GB921045A (enrdf_load_stackoverflow) |
| SE (1) | SE213190C1 (enrdf_load_stackoverflow) |
-
1959
- 1959-07-20 GB GB24882/59A patent/GB921045A/en not_active Expired
-
1960
- 1960-06-30 CH CH740360A patent/CH398884A/de unknown
- 1960-07-11 BE BE592849A patent/BE592849A/fr unknown
- 1960-07-12 ES ES0259611A patent/ES259611A1/es not_active Expired
- 1960-07-18 SE SE700060A patent/SE213190C1/sv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CH398884A (de) | 1966-03-15 |
| SE213190C1 (enrdf_load_stackoverflow) | 1967-05-30 |
| BE592849A (fr) | 1960-10-31 |
| ES259611A1 (es) | 1960-11-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE3059T1 (de) | Antibiotikum c-15003 pnd-0 und herstellung von antibiotikum c-15003 pnd. | |
| ES8305418A1 (es) | Un procedimiento para la preparacion de una nueva serie de macrolidas de la familia c-076-. | |
| FR2401992A1 (fr) | Culture de saccharopolyspora hirsuta | |
| KR840002904A (ko) | 슈도모나스속의 미생물 및 수용액내에서 메틸그룹을 함유한 화합물을 분해시키는 방법 | |
| ES8700253A1 (es) | Procedimiento para preparar compuestos de 5-alquil-1-fenil- -2-piperazinoalquilpirazolin-3-ona | |
| GB851311A (en) | Morpholine compounds and their production | |
| KR840002903A (ko) | 하이포미크로비움속의 미생물 및 수용액내에서 메틸그룹을 함유한 화합물을 분해시키는 방법 | |
| GB921045A (en) | Production of rifamycin b | |
| ES264960A1 (es) | Procedimiento de obtenciën de composiciones reveladoras fotograficas | |
| GB1147035A (en) | Seed-treatment nematocides, and certain novel 2,4-dihalophenylsulphonates having nematocidal properties | |
| GB1474896A (en) | Salts of phenylpyridazines and the preparation thereof | |
| KR930019834A (ko) | 질소-헤테로사이클릭-카르복시산의 미생물학적 히드록시화 방법 | |
| ES8702408A1 (es) | Un procedimiento para preparacion de nuevos analogos de mitomicina. | |
| GB1398411A (en) | Piperidine derivatives | |
| GB1165060A (en) | New N,N-Diglycidyl-Bis-Hydantoinyl Methane Derivatives, Process for their Production, and Use | |
| GB1422216A (en) | Phenyl-formamidine derivatives | |
| GB1387511A (en) | Method for the preparation of hydrogen peroxide | |
| GB975844A (en) | Improvements in or relating to the production of auramine dyes | |
| GB1059664A (en) | Process for the production of -ß-carotene | |
| GB918169A (en) | New 6-amino-penicillanic acid derivatives | |
| CA1246072A (en) | ISOCYANATO-AZETIDINEDIONES | |
| GB897046A (en) | Improvements in or relating to the production of penicillin compounds | |
| ES471356A1 (es) | Procedimiento de obtencion de r,s-2,3,5,6-tetrahidro-6-fenil-imidazo (2,1-b)-tiazole (tetramisole) | |
| ES439841A1 (es) | Un procedimiento para producir el compuesto 38.295 antibio- tico. | |
| GB1114666A (en) | Process for the production of ª-carotene |