GB9119874D0 - 3-cylopropyl-prop-2-enamide derivatives - Google Patents

3-cylopropyl-prop-2-enamide derivatives

Info

Publication number
GB9119874D0
GB9119874D0 GB919119874A GB9119874A GB9119874D0 GB 9119874 D0 GB9119874 D0 GB 9119874D0 GB 919119874 A GB919119874 A GB 919119874A GB 9119874 A GB9119874 A GB 9119874A GB 9119874 D0 GB9119874 D0 GB 9119874D0
Authority
GB
United Kingdom
Prior art keywords
cylopropyl
prop
enamide derivatives
enamide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
GB919119874A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roussel Laboratories Ltd
Original Assignee
Roussel Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Laboratories Ltd filed Critical Roussel Laboratories Ltd
Priority to GB919119874A priority Critical patent/GB9119874D0/en
Publication of GB9119874D0 publication Critical patent/GB9119874D0/en
Priority to GB929213972A priority patent/GB9213972D0/en
Priority to IL10279092A priority patent/IL102790A/en
Priority to CS922653A priority patent/CZ281674B6/cs
Priority to US07/944,830 priority patent/US5312830A/en
Priority to NZ244329A priority patent/NZ244329A/en
Priority to HU9202942A priority patent/HU210164B/hu
Priority to MX9205246A priority patent/MX9205246A/es
Priority to NO923603A priority patent/NO178299C/no
Priority to FI924145A priority patent/FI111248B/fi
Priority to AU24516/92A priority patent/AU649881B2/en
Priority to JP27072992A priority patent/JP3145803B2/ja
Priority to SU925052724A priority patent/RU2072987C1/ru
Priority to KR1019920016807A priority patent/KR100259686B1/ko
Priority to ZA927110A priority patent/ZA927110B/xx
Priority to CA002078466A priority patent/CA2078466C/fr
Priority to DE69215625T priority patent/DE69215625T2/de
Priority to AT92402554T priority patent/ATE145893T1/de
Priority to BR929203643A priority patent/BR9203643A/pt
Priority to DK92402554.7T priority patent/DK0533573T3/da
Priority to EP92402554A priority patent/EP0533573B1/fr
Priority to ES92402554T priority patent/ES2095434T3/es
Priority to CN92110722A priority patent/CN1028863C/zh
Priority to TW081107367A priority patent/TW213443B/zh
Priority to US08/184,566 priority patent/US5389652A/en
Priority to GR960401134T priority patent/GR3022423T3/el
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/24—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the same saturated acyclic carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/31—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing rings other than six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/38—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atom of at least one amino group being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfones
    • C07C317/40—Y being a hydrogen or a carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/40—Y being a hydrogen or a carbon atom
    • C07C323/41—Y being a hydrogen or an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB919119874A 1991-09-17 1991-09-17 3-cylopropyl-prop-2-enamide derivatives Pending GB9119874D0 (en)

Priority Applications (26)

Application Number Priority Date Filing Date Title
GB919119874A GB9119874D0 (en) 1991-09-17 1991-09-17 3-cylopropyl-prop-2-enamide derivatives
GB929213972A GB9213972D0 (en) 1991-09-17 1992-07-01 3-cycloalkyl-prop-2-enamide derivatives
IL10279092A IL102790A (en) 1991-09-17 1992-08-11 History of 3-cycloalkyl-prop-2-anamide
CS922653A CZ281674B6 (cs) 1991-09-17 1992-08-27 Deriváty 3-cykloalkylpropen-2-amidu, způsob jejich výroby a léčiva na jejich bázi
US07/944,830 US5312830A (en) 1991-09-17 1992-09-14 3-cycloalkyl-prop-2-enamides
NZ244329A NZ244329A (en) 1991-09-17 1992-09-14 3-cycloalkyl-prop-2-enamide derivatives, pharmaceutical compositions, and intermediates therefor
HU9202942A HU210164B (en) 1991-09-17 1992-09-15 Process for preparing 3-cycloalkyl-prop-2-enamide derivatives and pharmaceutical compn. contg. them
MX9205246A MX9205246A (es) 1991-09-17 1992-09-15 Nuevos derivados de 3-cicloalquil-2-propenamida, sus formas tautomeras y sus sales, procedimiento de preparacion, aplicacion como medicamentos y composiciones que las contienen.
KR1019920016807A KR100259686B1 (ko) 1991-09-17 1992-09-16 3-시클로알킬-프로프-2-엔아미드 유도체
SU925052724A RU2072987C1 (ru) 1991-09-17 1992-09-16 Производные 3-циклоалкилпропен-2-амида или их аддитивные соли с минеральными или органическими основаниями, способ их получения и фармацевтическая композиция, обладающая противовоспалительной активностью
FI924145A FI111248B (fi) 1991-09-17 1992-09-16 Menetelmä 3-sykloalkyyliprop-2-eeniamidijohdannaisten ja niiden emäsadditiosuolojen valmistamiseksi
AU24516/92A AU649881B2 (en) 1991-09-17 1992-09-16 3-cycloalkyl-prop-2-enamide derivatives
JP27072992A JP3145803B2 (ja) 1991-09-17 1992-09-16 ３−シクロアルキル−２−プロペンアミド誘導体
NO923603A NO178299C (no) 1991-09-17 1992-09-16 Nye 3-sykloalkyl-propen-2-amidderivater, farmasöytiske preparater inneholdende disse som aktiv bestanddel og nye mellomprodukter som er anvendelige for fremstilling av derivatene
CN92110722A CN1028863C (zh) 1991-09-17 1992-09-17 3-环烷基-丙-2-烯酰胺衍生物
AT92402554T ATE145893T1 (de) 1991-09-17 1992-09-17 Derivate des 3-cyclo-alkylpropen-2-amide, deren tautomere und salze und ihre verwendung als entzündungshemmende wirkstoffe
CA002078466A CA2078466C (fr) 1991-09-17 1992-09-17 Nouveaux derives du 3-cycloalkyl-propen-2-amide, leurs formes tautomeres et leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
DE69215625T DE69215625T2 (de) 1991-09-17 1992-09-17 Derivate des 3-Cyclo-alkylpropen-2-amide, deren Tautomere und Salze und ihre Verwendung als entzündungshemmende Wirkstoffe
ZA927110A ZA927110B (en) 1991-09-17 1992-09-17 3-cycloalkyl-prop-2-enamide derivatives.
BR929203643A BR9203643A (pt) 1991-09-17 1992-09-17 Derivados de 3-cicloalquil-propen-2-amida e processo para sua preparacao,medicamentos e composicoes farmaceuticas
DK92402554.7T DK0533573T3 (da) 1991-09-17 1992-09-17 Derivater af 3-cyclo-alkylpropen-2-amider, deres tautomere og deres salte og deres anvendelse som betændelseshæmmende stoffer
EP92402554A EP0533573B1 (fr) 1991-09-17 1992-09-17 Nouveaux dérivés du 3-cyclo alkyl-propen-2-amide, leurs formes tautomères et leurs sels, procédé de préparation, application à titre de médicaments et compositions les renfermant
ES92402554T ES2095434T3 (es) 1991-09-17 1992-09-17 Nuevos derivados del 3-cicloalquil-propen-2-amida, sus formas tautomeras y sus sales, procedimiento de preparacion, aplicacion como medicamentos, y composiciones que los contienen.
TW081107367A TW213443B (ko) 1991-09-17 1992-09-18
US08/184,566 US5389652A (en) 1991-09-17 1994-01-21 3-cycloalkyl-prop-2-enamides
GR960401134T GR3022423T3 (en) 1991-09-17 1997-01-30 Derivatives of 3-cyclo alkyl-propen-2-amide, their tautomeres and salts and their use as antiinflammatory agents

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919119874A GB9119874D0 (en) 1991-09-17 1991-09-17 3-cylopropyl-prop-2-enamide derivatives

Publications (1)

Publication Number Publication Date
GB9119874D0 true GB9119874D0 (en) 1991-10-30

Family

ID=10701567

Family Applications (2)

Application Number Title Priority Date Filing Date
GB919119874A Pending GB9119874D0 (en) 1991-09-17 1991-09-17 3-cylopropyl-prop-2-enamide derivatives
GB929213972A Pending GB9213972D0 (en) 1991-09-17 1992-07-01 3-cycloalkyl-prop-2-enamide derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB929213972A Pending GB9213972D0 (en) 1991-09-17 1992-07-01 3-cycloalkyl-prop-2-enamide derivatives

Country Status (5)

Country Link
KR (1) KR100259686B1 (ko)
GB (2) GB9119874D0 (ko)
RU (1) RU2072987C1 (ko)
TW (1) TW213443B (ko)
ZA (1) ZA927110B (ko)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4414395A (en) * 1980-03-13 1983-11-08 Ciba-Geigy Corporation Process for the manufacture of hydrazono-isoindolines
US5034410A (en) * 1989-10-11 1991-07-23 Syntex (U.S.A.) Inc. Anthelmintically active benzenepropanamide derivatives

Also Published As

Publication number Publication date
TW213443B (ko) 1993-09-21
ZA927110B (en) 1993-09-17
GB9213972D0 (en) 1992-08-12
KR930005967A (ko) 1993-04-20
RU2072987C1 (ru) 1997-02-10
KR100259686B1 (ko) 2000-06-15

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