GB894192A - Improvements in and relating to tetrahydrofurane derivatives - Google Patents
Improvements in and relating to tetrahydrofurane derivativesInfo
- Publication number
- GB894192A GB894192A GB38399/58A GB3839958A GB894192A GB 894192 A GB894192 A GB 894192A GB 38399/58 A GB38399/58 A GB 38399/58A GB 3839958 A GB3839958 A GB 3839958A GB 894192 A GB894192 A GB 894192A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- halides
- steric
- racemic
- oxo
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000007984 tetrahydrofuranes Chemical class 0.000 title 1
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 2
- -1 methyl halides Chemical class 0.000 abstract 2
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 2
- NPWZPONFDZBXPD-UHFFFAOYSA-N 5-(dimethylamino)-2-methylfuran-3-one Chemical compound CC1OC(=CC1=O)N(C)C NPWZPONFDZBXPD-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- UQOFGTXDASPNLL-XHNCKOQMSA-N Muscarine Chemical compound C[C@@H]1O[C@H](C[N+](C)(C)C)C[C@H]1O UQOFGTXDASPNLL-XHNCKOQMSA-N 0.000 abstract 1
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 abstract 1
- 239000003513 alkali Substances 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 239000002585 base Substances 0.000 abstract 1
- 150000004820 halides Chemical class 0.000 abstract 1
- 238000005984 hydrogenation reaction Methods 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 229910052987 metal hydride Inorganic materials 0.000 abstract 1
- 150000004681 metal hydrides Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical group 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 abstract 1
Landscapes
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Racemic 2 - methyl - 3 - hydroxy - 5 - dimethylaminomehyl tetrahydrofuran of the steric ormula <FORM:0894192/IV (b)/1> is prepared by reducing 2-methyl-3-oxo-5-dimethyl-aminomethyl tetrahydrofuran of the steric formula <FORM:0894192/IV (b)/2> or a mixture in which this stereoisomer forms a substantial part, with an alkali metal-earth metal hydride. The invention may also be combined with the steps of producing the starting material either by the hydrogenation in the presence of palladium charcoal or by reduction with lithium aluminium hydride of 2 - methyl - 3 - oxo - 5 - dimethylamino - 2, 3 - dihydrofuran. The basic alcohol may be converted into halides of the racemic muscarine base by reaction with methyl halides and into quaternary salts in general by reaction with alkyl and aralkyl halides and sulphates. Specification 894,191 is referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH894192X | 1957-11-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB894192A true GB894192A (en) | 1962-04-18 |
Family
ID=4546054
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB38399/58A Expired GB894192A (en) | 1957-11-29 | 1958-11-28 | Improvements in and relating to tetrahydrofurane derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB894192A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2119344A (en) * | 1982-03-16 | 1983-11-16 | Zoeller Kipper | Device for emptying containers into a collector |
-
1958
- 1958-11-28 GB GB38399/58A patent/GB894192A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2119344A (en) * | 1982-03-16 | 1983-11-16 | Zoeller Kipper | Device for emptying containers into a collector |
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