GB890471A - New bishydrazinium salts, their production and pharmaceutical compositions containing them - Google Patents
New bishydrazinium salts, their production and pharmaceutical compositions containing themInfo
- Publication number
- GB890471A GB890471A GB405060A GB405060A GB890471A GB 890471 A GB890471 A GB 890471A GB 405060 A GB405060 A GB 405060A GB 405060 A GB405060 A GB 405060A GB 890471 A GB890471 A GB 890471A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- bishydrazinium
- pharmaceutical compositions
- anions
- specifications
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/28—Nitrogen atoms
- C07D295/30—Nitrogen atoms non-acylated
Abstract
The invention comprises compounds of the formula <FORM:0890471/IV (b)/1> (wherein n is an integer and X is an anion bearing the charge p). They may be prepared by reacting chloramine or hydroxylamine-O-sulphonic acid acid with the appropriate dimorpholinoalkane of the formula <FORM:0890471/IV (b)/2> which, in turn, may be prepared by the reaction of morpholine with the appropriate alkylene dihalide and subsequent liberation of the free base from the hydrogen halide acid-addition salt first formed. Anions may be exchanged by meta thesis. Examples are given and an extensive list of anions X is provided. A by-product of one example is 4-amino-4-[(4-morpholino)ethyl]-morpholinium chloride. Specification 858,488 and U.S.A. Specifications 2,678,258 and 2,710,248 are referred to.ALSO:Pharmaceutical compositions comprise a bishydrazinium salt of the formula <FORM:0890471/VI/1> (wherein n is an integer and X is an anion bearing the charge p) in admixture with a solid or liquid pharmaceutical carrier. Specific examples of X are those listed in Specification 880,974. Specification 858,488 and U.S.A. Specifications 2,678,258 and 2,710,248 also are referred to.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB405060A GB890471A (en) | 1960-02-04 | 1960-02-04 | New bishydrazinium salts, their production and pharmaceutical compositions containing them |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB405060A GB890471A (en) | 1960-02-04 | 1960-02-04 | New bishydrazinium salts, their production and pharmaceutical compositions containing them |
Publications (1)
Publication Number | Publication Date |
---|---|
GB890471A true GB890471A (en) | 1962-02-28 |
Family
ID=9769779
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB405060A Expired GB890471A (en) | 1960-02-04 | 1960-02-04 | New bishydrazinium salts, their production and pharmaceutical compositions containing them |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB890471A (en) |
-
1960
- 1960-02-04 GB GB405060A patent/GB890471A/en not_active Expired
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