GB886183A - Quaternary salts of tropine compounds - Google Patents
Quaternary salts of tropine compoundsInfo
- Publication number
- GB886183A GB886183A GB37836/58A GB3783658A GB886183A GB 886183 A GB886183 A GB 886183A GB 37836/58 A GB37836/58 A GB 37836/58A GB 3783658 A GB3783658 A GB 3783658A GB 886183 A GB886183 A GB 886183A
- Authority
- GB
- United Kingdom
- Prior art keywords
- compounds
- tropine
- tropinium
- reacting
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- CYHOMWAPJJPNMW-JIGDXULJSA-N tropine Chemical class C1[C@@H](O)C[C@H]2CC[C@@H]1N2C CYHOMWAPJJPNMW-JIGDXULJSA-N 0.000 title abstract 2
- 150000003839 salts Chemical group 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- -1 halogen ion Chemical class 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 abstract 2
- YYMCYJLIYNNOMK-MEKDEQNOSA-N (1r,5s)-8-azabicyclo[3.2.1]octan-3-ol Chemical compound C1C(O)C[C@@H]2CC[C@H]1N2 YYMCYJLIYNNOMK-MEKDEQNOSA-N 0.000 abstract 1
- CYHOMWAPJJPNMW-DHBOJHSNSA-O (1r,5s)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-ol Chemical compound C1C(O)C[C@H]2CC[C@@H]1[NH+]2C CYHOMWAPJJPNMW-DHBOJHSNSA-O 0.000 abstract 1
- VMZCDNSFRSVYKQ-UHFFFAOYSA-N 2-phenylacetyl chloride Chemical compound ClC(=O)CC1=CC=CC=C1 VMZCDNSFRSVYKQ-UHFFFAOYSA-N 0.000 abstract 1
- XQJMXPAEFMWDOZ-UHFFFAOYSA-N 3exo-benzoyloxy-tropane Natural products CN1C(C2)CCC1CC2OC(=O)C1=CC=CC=C1 XQJMXPAEFMWDOZ-UHFFFAOYSA-N 0.000 abstract 1
- OFOBLEOULBTSOW-UHFFFAOYSA-N Malonic acid Chemical compound OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 abstract 1
- QQXLDOJGLXJCSE-UHFFFAOYSA-N N-methylnortropinone Natural products C1C(=O)CC2CCC1N2C QQXLDOJGLXJCSE-UHFFFAOYSA-N 0.000 abstract 1
- YYMCYJLIYNNOMK-UHFFFAOYSA-N N-normethyltropine Natural products C1C(O)CC2CCC1N2 YYMCYJLIYNNOMK-UHFFFAOYSA-N 0.000 abstract 1
- QIZDQFOVGFDBKW-DHBOJHSNSA-N Pseudotropine Natural products OC1C[C@@H]2[N+](C)[C@H](C1)CC2 QIZDQFOVGFDBKW-DHBOJHSNSA-N 0.000 abstract 1
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 150000001350 alkyl halides Chemical class 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000000732 arylene group Chemical group 0.000 abstract 1
- 230000000903 blocking effect Effects 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 238000010438 heat treatment Methods 0.000 abstract 1
- 150000003840 hydrochlorides Chemical class 0.000 abstract 1
- 230000002232 neuromuscular Effects 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
- C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB37836/58A GB886183A (en) | 1958-11-25 | 1958-11-25 | Quaternary salts of tropine compounds |
| BE584976A BE584976A (fr) | 1958-11-25 | 1959-11-24 | Sels quaternaires de composés tropiniques |
| FR837275A FR508M (enrdf_load_stackoverflow) | 1958-11-25 | 1960-08-30 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB37836/58A GB886183A (en) | 1958-11-25 | 1958-11-25 | Quaternary salts of tropine compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB886183A true GB886183A (en) | 1962-01-03 |
Family
ID=10399345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB37836/58A Expired GB886183A (en) | 1958-11-25 | 1958-11-25 | Quaternary salts of tropine compounds |
Country Status (3)
| Country | Link |
|---|---|
| BE (1) | BE584976A (enrdf_load_stackoverflow) |
| FR (1) | FR508M (enrdf_load_stackoverflow) |
| GB (1) | GB886183A (enrdf_load_stackoverflow) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999021854A1 (en) * | 1997-10-24 | 1999-05-06 | Newlaxant Llc | Bis-quaternary ammonium derivatives as neuromuscular relaxants |
| CN109369536A (zh) * | 2018-12-10 | 2019-02-22 | 怀化学院 | 对苯二甲酸酯季铵盐及其制备方法、用途 |
-
1958
- 1958-11-25 GB GB37836/58A patent/GB886183A/en not_active Expired
-
1959
- 1959-11-24 BE BE584976A patent/BE584976A/fr unknown
-
1960
- 1960-08-30 FR FR837275A patent/FR508M/fr active Active
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999021854A1 (en) * | 1997-10-24 | 1999-05-06 | Newlaxant Llc | Bis-quaternary ammonium derivatives as neuromuscular relaxants |
| US5990124A (en) * | 1997-10-24 | 1999-11-23 | Gyermek; Laszlo | Neuromuscular relaxants |
| US6274757B1 (en) | 1997-10-24 | 2001-08-14 | Newlaxant Llc | Neuromuscular relaxants |
| US6274623B1 (en) | 1997-10-24 | 2001-08-14 | Newlaxant Llc | Neuromuscular relaxants |
| RU2199539C2 (ru) * | 1997-10-24 | 2003-02-27 | Ньюлаксант Ллс. | Бис-кватернизованные производные аммония, фармацевтическая композиция на их основе |
| CN109369536A (zh) * | 2018-12-10 | 2019-02-22 | 怀化学院 | 对苯二甲酸酯季铵盐及其制备方法、用途 |
Also Published As
| Publication number | Publication date |
|---|---|
| BE584976A (fr) | 1960-05-24 |
| FR508M (enrdf_load_stackoverflow) | 1961-05-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| GB828762A (en) | Amino substituted triphenylethylenes and preparation thereof | |
| GB886183A (en) | Quaternary salts of tropine compounds | |
| GB943603A (en) | Dibenzocycloheptane derivatives | |
| GB954196A (en) | Method of preparing amino esters | |
| GB893269A (en) | New 3,5-diketo-1,2,4-triazolidine derivatives | |
| GB1058514A (en) | N-(tertiary-aminoalkyl)-methylenedioxybenzamides and their preparation | |
| GB888535A (en) | Indole compounds | |
| GB932531A (en) | Substituted amides | |
| GB946303A (en) | Novel steroids and process for their manufacture | |
| GB849793A (en) | Substituted benzimidazoles | |
| GB1066843A (en) | Azaphenthiazine derivatives | |
| GB1059839A (en) | Process for preparing ketones and novel ketones so prepared | |
| GB858719A (en) | New quaternary ammonium compounds and a process for their manufacture | |
| GB927698A (en) | Pharmaceutically useful sulphonylamido derivatives and process of preparing them | |
| GB1394563A (en) | Process for preparing benzamides | |
| GB830825A (en) | Improvements in and relating to diquaternary compounds | |
| GB996253A (en) | Substituted hydrazides | |
| GB1098598A (en) | Substituted n-tertiary-aminoalkyl-benzamides and their preparation | |
| GB980878A (en) | Condensation products of tetracyclines, preparations containing them and process of preparing them | |
| ES355189A1 (es) | Un procedimiento de preparacion de las n-(aminoterciario - alcohil-2-alcohileno-(o alquinilo)-oxi-benzamidas. | |
| GB808926A (en) | New tropeine derivatives | |
| GB878600A (en) | Thiopyrimidine derivatives | |
| ES247867A1 (es) | Un procedimiento para la preparacion de compuestos terapeuticos | |
| GB910999A (en) | 16,17ª--oxido-21-aminoalkyl-í~-pregnen-3ª--ol-20-one compounds | |
| GB886946A (en) | A process for the manufacture of carbazole compounds and novel carbazole compounds occurring therein |