GB854343A - Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids - Google Patents
Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroidsInfo
- Publication number
- GB854343A GB854343A GB814058A GB814058A GB854343A GB 854343 A GB854343 A GB 854343A GB 814058 A GB814058 A GB 814058A GB 814058 A GB814058 A GB 814058A GB 854343 A GB854343 A GB 854343A
- Authority
- GB
- United Kingdom
- Prior art keywords
- dione
- oxo
- steroids
- diene
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises 17a -ethynyl-and17a -methyl - 17b - hydroxyandrosta - 1:4:6 - trien - 3 - one, pregna-1:4:6-triene-3:20-dione and -3:11:20-trione, 16a -methylpregna - 1 : 4-diene- 3:20-dione, 20:20-ethylenedioxypregna-1 : 4-dien-3-one, cholesta-1 : 4-diene-3 : 6-dione, the acetonide of 16a -17a -dihydroxypregna-1 : 4-diene-3 : 20-dione, 17b -acetoxy - 2 - methylandrosta - 1:4 - dien - 3 - one and pregna - 1:4:9(11) - triene - 3:20 - dione, and a process for the preparation of 3-oxo-\se1:4- and -\se1:4:6-6-demethyl-steroids which comprises treating the corresponding \se4- or \se4:6- compound with 2:3-dicyano-1:4-benzoquinone, which may be additionally substituted with one or two chlorine atoms, in a solvent, advantageously in the presence of a catalytic quantity of p-nitrophenol. The \se1:4:6-compounds obtained can be converted into aromatic steroids by reaction with toluene-p-sulphonic acid in acetic anhydride.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB814058A GB854343A (en) | 1958-03-13 | 1958-03-13 | Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids |
BE576678A BE576678A (en) | 1958-03-13 | 1959-03-13 | Process for the preparation of steroids and products obtained. |
CH7075959A CH371445A (en) | 1958-03-13 | 1959-03-13 | Process for the preparation of 3-oxo-1,4- and 3-oxo-1,4,6-steroids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB814058A GB854343A (en) | 1958-03-13 | 1958-03-13 | Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids |
Publications (1)
Publication Number | Publication Date |
---|---|
GB854343A true GB854343A (en) | 1960-11-16 |
Family
ID=9846515
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB814058A Expired GB854343A (en) | 1958-03-13 | 1958-03-13 | Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids |
Country Status (2)
Country | Link |
---|---|
CH (1) | CH371445A (en) |
GB (1) | GB854343A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3077471A (en) * | 1961-08-04 | 1963-02-12 | Olin Mathieson | Steroids of the 19-norpregnane series |
US3101353A (en) * | 1961-07-19 | 1963-08-20 | Syntex Corp | 2-formyl-delta'-androstenes and delta1,4-androstadienes |
US3361744A (en) * | 1962-07-18 | 1968-01-02 | American Cyanamid Co | Novel 17-hydrocarbon substituted progesterones, intermediates and methods of preparing the same |
-
1958
- 1958-03-13 GB GB814058A patent/GB854343A/en not_active Expired
-
1959
- 1959-03-13 CH CH7075959A patent/CH371445A/en unknown
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3101353A (en) * | 1961-07-19 | 1963-08-20 | Syntex Corp | 2-formyl-delta'-androstenes and delta1,4-androstadienes |
US3077471A (en) * | 1961-08-04 | 1963-02-12 | Olin Mathieson | Steroids of the 19-norpregnane series |
US3361744A (en) * | 1962-07-18 | 1968-01-02 | American Cyanamid Co | Novel 17-hydrocarbon substituted progesterones, intermediates and methods of preparing the same |
Also Published As
Publication number | Publication date |
---|---|
CH371445A (en) | 1963-08-31 |
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