GB854343A - Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids - Google Patents

Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids

Info

Publication number
GB854343A
GB854343A GB814058A GB814058A GB854343A GB 854343 A GB854343 A GB 854343A GB 814058 A GB814058 A GB 814058A GB 814058 A GB814058 A GB 814058A GB 854343 A GB854343 A GB 854343A
Authority
GB
United Kingdom
Prior art keywords
dione
oxo
steroids
diene
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB814058A
Inventor
George Oliver Weston
Derek Burn
David Neville Kirk
Vladimir Petrow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BDH Chemicals Ltd
Original Assignee
BDH Chemicals Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BDH Chemicals Ltd filed Critical BDH Chemicals Ltd
Priority to GB814058A priority Critical patent/GB854343A/en
Priority to BE576678A priority patent/BE576678A/en
Priority to CH7075959A priority patent/CH371445A/en
Publication of GB854343A publication Critical patent/GB854343A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises 17a -ethynyl-and17a -methyl - 17b - hydroxyandrosta - 1:4:6 - trien - 3 - one, pregna-1:4:6-triene-3:20-dione and -3:11:20-trione, 16a -methylpregna - 1 : 4-diene- 3:20-dione, 20:20-ethylenedioxypregna-1 : 4-dien-3-one, cholesta-1 : 4-diene-3 : 6-dione, the acetonide of 16a -17a -dihydroxypregna-1 : 4-diene-3 : 20-dione, 17b -acetoxy - 2 - methylandrosta - 1:4 - dien - 3 - one and pregna - 1:4:9(11) - triene - 3:20 - dione, and a process for the preparation of 3-oxo-\se1:4- and -\se1:4:6-6-demethyl-steroids which comprises treating the corresponding \se4- or \se4:6- compound with 2:3-dicyano-1:4-benzoquinone, which may be additionally substituted with one or two chlorine atoms, in a solvent, advantageously in the presence of a catalytic quantity of p-nitrophenol. The \se1:4:6-compounds obtained can be converted into aromatic steroids by reaction with toluene-p-sulphonic acid in acetic anhydride.
GB814058A 1958-03-13 1958-03-13 Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids Expired GB854343A (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB814058A GB854343A (en) 1958-03-13 1958-03-13 Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids
BE576678A BE576678A (en) 1958-03-13 1959-03-13 Process for the preparation of steroids and products obtained.
CH7075959A CH371445A (en) 1958-03-13 1959-03-13 Process for the preparation of 3-oxo-1,4- and 3-oxo-1,4,6-steroids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB814058A GB854343A (en) 1958-03-13 1958-03-13 Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids

Publications (1)

Publication Number Publication Date
GB854343A true GB854343A (en) 1960-11-16

Family

ID=9846515

Family Applications (1)

Application Number Title Priority Date Filing Date
GB814058A Expired GB854343A (en) 1958-03-13 1958-03-13 Process for the preparation of 3-oxo-í¸ and 3-oxo-í¸-steroids

Country Status (2)

Country Link
CH (1) CH371445A (en)
GB (1) GB854343A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3077471A (en) * 1961-08-04 1963-02-12 Olin Mathieson Steroids of the 19-norpregnane series
US3101353A (en) * 1961-07-19 1963-08-20 Syntex Corp 2-formyl-delta'-androstenes and delta1,4-androstadienes
US3361744A (en) * 1962-07-18 1968-01-02 American Cyanamid Co Novel 17-hydrocarbon substituted progesterones, intermediates and methods of preparing the same

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3101353A (en) * 1961-07-19 1963-08-20 Syntex Corp 2-formyl-delta'-androstenes and delta1,4-androstadienes
US3077471A (en) * 1961-08-04 1963-02-12 Olin Mathieson Steroids of the 19-norpregnane series
US3361744A (en) * 1962-07-18 1968-01-02 American Cyanamid Co Novel 17-hydrocarbon substituted progesterones, intermediates and methods of preparing the same

Also Published As

Publication number Publication date
CH371445A (en) 1963-08-31

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