GB912038A - 11ª--methyl-5ª--steroids - Google Patents
11ª--methyl-5ª--steroidsInfo
- Publication number
- GB912038A GB912038A GB2289160A GB2289160A GB912038A GB 912038 A GB912038 A GB 912038A GB 2289160 A GB2289160 A GB 2289160A GB 2289160 A GB2289160 A GB 2289160A GB 912038 A GB912038 A GB 912038A
- Authority
- GB
- United Kingdom
- Prior art keywords
- methyl
- steroids
- oxo
- spirostan
- pregnane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
The invention comprises (1) a process for the preparation of 11b -methyl-5a -steroids having at the 3-position a hydroxy, acyloxy, oxo, dimethoxy or cyclic ketal group by catalytically hydrogenating the corresponding 11-methylene-5a -steroids in solution in an inert solvent; and (2) the new steroids, 3b -acetoxy-11b - methyl - 5a ,25D - spirostan; 3b ,20b -diacetoxy-11b -methyl - 5a - pregnane; 17b - propionyloxy-11b -methyl-5a -androstan-3-one; and 17b - propionyloxy-3,3-dimethoxy-11b -methyl-5a -androstane. It is stated that the process is applicable to steroids of the spirostan, pregnane and androstane series which may contain 3b -, 17b - or 20-acyloxy or -hydroxy groups and 3 - oxo or protected 3 - oxo groups. Unprotected oxo groups which are concomitantly reduced may be re - oxidized. Examples are given. Specification 912,036 is referred to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2289160A GB912038A (en) | 1960-06-30 | 1960-06-30 | 11ª--methyl-5ª--steroids |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB2289160A GB912038A (en) | 1960-06-30 | 1960-06-30 | 11ª--methyl-5ª--steroids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB912038A true GB912038A (en) | 1962-12-05 |
Family
ID=10186723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2289160A Expired GB912038A (en) | 1960-06-30 | 1960-06-30 | 11ª--methyl-5ª--steroids |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB912038A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1042352A1 (en) * | 1997-11-26 | 2000-10-11 | Research Triangle Institute | Androgenic steroid compounds and a method of making and using the same |
-
1960
- 1960-06-30 GB GB2289160A patent/GB912038A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1042352A1 (en) * | 1997-11-26 | 2000-10-11 | Research Triangle Institute | Androgenic steroid compounds and a method of making and using the same |
| EP1042352A4 (en) * | 1997-11-26 | 2004-12-22 | Res Triangle Inst | Androgenic steroid compounds and a method of making and using the same |
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