GB851674A - New derivatives of trioxo-2,4,6-piperidine and the process of preparing same - Google Patents
New derivatives of trioxo-2,4,6-piperidine and the process of preparing sameInfo
- Publication number
- GB851674A GB851674A GB13517/59A GB1351759A GB851674A GB 851674 A GB851674 A GB 851674A GB 13517/59 A GB13517/59 A GB 13517/59A GB 1351759 A GB1351759 A GB 1351759A GB 851674 A GB851674 A GB 851674A
- Authority
- GB
- United Kingdom
- Prior art keywords
- formula
- trioxo
- piperidine
- ester
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
The invention comprises 2:4:6-trioxopiperidine derivatives of the general formula <FORM:0851674/IV(b)/1> (wherein R1,R2,R3 and R4 each represent an aryl or alkyl radical and R5 represents hydrogen or an alkyl or dialkylaminoalkyl radical), and the preparation thereof by condensing a disubstituted cyanacetyl chloride of the formula <FORM:0851674/IV(b)/2> with an ester of a disubstituted acetic acid of the formula <FORM:0851674/IV(b)/3> cyclizing the resulting tetrasubstituted cyanoacetylacetic ester to give a compound (I) in which R5 is hydrogen, and, if desired, treating this with an alkylating or dialkylaminoalkylating agent. The products are useful as sedative, anticonvulsant and hypnotic agents in human and veterinary medicine, and as intermediates in the preparation of other active substances.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR851674X | 1958-04-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB851674A true GB851674A (en) | 1960-10-19 |
Family
ID=9324746
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB13517/59A Expired GB851674A (en) | 1958-04-23 | 1959-04-21 | New derivatives of trioxo-2,4,6-piperidine and the process of preparing same |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB851674A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3140287A (en) * | 1962-08-16 | 1964-07-07 | Eastman Kodak Co | Method for preparing tetraalkyl-3-oxoglutarimides |
-
1959
- 1959-04-21 GB GB13517/59A patent/GB851674A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3140287A (en) * | 1962-08-16 | 1964-07-07 | Eastman Kodak Co | Method for preparing tetraalkyl-3-oxoglutarimides |
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