GB795401A - Improvements in or relating to the production of itaconic acid - Google Patents

Improvements in or relating to the production of itaconic acid

Info

Publication number
GB795401A
GB795401A GB3116/56A GB311656A GB795401A GB 795401 A GB795401 A GB 795401A GB 3116/56 A GB3116/56 A GB 3116/56A GB 311656 A GB311656 A GB 311656A GB 795401 A GB795401 A GB 795401A
Authority
GB
United Kingdom
Prior art keywords
nutrient medium
itaconic acid
sulphate
adsorbent
adsorbents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB3116/56A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ROYAL NORWEGIAN COUNCIL FOR SC
Original Assignee
ROYAL NORWEGIAN COUNCIL FOR SC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ROYAL NORWEGIAN COUNCIL FOR SC filed Critical ROYAL NORWEGIAN COUNCIL FOR SC
Publication of GB795401A publication Critical patent/GB795401A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids

Abstract

Itaconic acid is produced by the fermentation of an aqueous sugar-containing nutrient medium by the aerobic cultivation therein of eumycetes, such as species of the genus Aspergillus, which will convert sugar into itaconic acid, characterized in that the nutrient medium contains one or more finely divided adsorbents. Suitable such adsorbents are anhydrous calcium sulphate, kaolin, bleaching earth, fuller's earth or anhydrous silicic acid, used singly or in admixture. The adsorbents may be activated in known manner, an example being the heat activation of gypsum. With an average particle size within the range of 1 to 50m , a suitable concentration of adsorbent is 0.5 to 5 grams per litre of nutrient medium. In examples, a nutrient medium comprising sucrose, ammonium sulphate, magnesium sulphate, monobasic potassium sulphate in tap water with (1) heat-activated calcium sulphate, (2) kaolin, or (3) fuller's earth as the adsorbent, is sterilized and then inoculated with Aspergillus terreus at 32 DEG C. under atmospheric pressure with careful temperature control, stirring and aeration, whereby itaconic acid is produced. A comparative example using the same nutrient medium but with the omission of the adsorbent gives lower yields of itaconic acid. Specification 602,866 is referred to.
GB3116/56A 1955-01-31 1956-01-31 Improvements in or relating to the production of itaconic acid Expired GB795401A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NO795401X 1955-01-31

Publications (1)

Publication Number Publication Date
GB795401A true GB795401A (en) 1958-05-21

Family

ID=19907065

Family Applications (1)

Application Number Title Priority Date Filing Date
GB3116/56A Expired GB795401A (en) 1955-01-31 1956-01-31 Improvements in or relating to the production of itaconic acid

Country Status (1)

Country Link
GB (1) GB795401A (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078217A (en) * 1960-07-01 1963-02-19 Miles Lab Process for the production of itaconic acid
US5457040A (en) * 1993-03-12 1995-10-10 Rhone-Poulenc Chimie Production of itaconic acid by fermentation
US5637485A (en) * 1993-03-12 1997-06-10 Rhone-Poulenc Chimie Production of itaconic acid by fermentation

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3078217A (en) * 1960-07-01 1963-02-19 Miles Lab Process for the production of itaconic acid
US5457040A (en) * 1993-03-12 1995-10-10 Rhone-Poulenc Chimie Production of itaconic acid by fermentation
US5637485A (en) * 1993-03-12 1997-06-10 Rhone-Poulenc Chimie Production of itaconic acid by fermentation

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