GB755644A - Improvements in or relating to processes for the recovery of growth-stimulating factors - Google Patents

Improvements in or relating to processes for the recovery of growth-stimulating factors

Info

Publication number
GB755644A
GB755644A GB4184/54A GB418454A GB755644A GB 755644 A GB755644 A GB 755644A GB 4184/54 A GB4184/54 A GB 4184/54A GB 418454 A GB418454 A GB 418454A GB 755644 A GB755644 A GB 755644A
Authority
GB
United Kingdom
Prior art keywords
contacting
alcohol
factors
solutions
activated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4184/54A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Charles Pfizer and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc, Charles Pfizer and Co Inc filed Critical Pfizer Inc
Publication of GB755644A publication Critical patent/GB755644A/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/10Animal feeding-stuffs obtained by microbiological or biochemical processes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K10/00Animal feeding-stuffs
    • A23K10/20Animal feeding-stuffs from material of animal origin
    • A23K10/22Animal feeding-stuffs from material of animal origin from fish
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Food Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Physiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Husbandry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Mycology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biochemistry (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

Vitamins are obtained from micro-organism fermentation broth residues or fish solubles by contacting their aqueous solutions with an activated earth or a water-miscible C1-3 alcohol or ketone, or a phenolic compound or activated carbon when in this latter case the vitamins are eluted therefrom by a mixture of a base, water and a C1-3 alcohol or ketone, or combinations of such processes. Hot dimethyl formamide may be used to extract the vitamins from dry concentrates obtained as above, or from dry fish solubles or solid fermentation residues or to the solutions treated as above, or combinations thereof. The vitamins, in the original solution or after concentration can be separated into two active fractions by contacting their aqueous solutions with a cationexchange resin.ALSO:Growth-stimulating factors are obtained from micro-organism fermentation broth residues or fish solubles by contacting their aqueous solutions with an activated earth or a water-miscible alcohol or ketone having 1-3 carbon atoms. In modifications, the solution is contacted with activated carbon and the factor eluted therefrom with a mixture of a base, water and an alcohol having 1-3 carbon atoms, or the adsorption on carbon followed by elution may be applied to concentrates obtained from contacting with activated earths or C1-3 alcohol or ketone or a combination of both. Dry concentrates of the factor may be extracted with hot dimethylformamide, or such extraction may be applied directly to dry fish solubles or solid fermentation residues, or to the solutions contacted with activated earths or C1-3 alcohols or ketones, or to solutions contacted with activated carbon and subsequent eluation, or to combinations thereof. Phenolic compounds may be used to extract the factors, either directly on the original solutions or after some concentration of the factors has been obtained. The factors in the original solution or after concentration can be separated into two active fractions by contacting their aqueous solutions with a cation-exchange resin. The factors are added to food for animals.
GB4184/54A 1953-02-17 1954-02-12 Improvements in or relating to processes for the recovery of growth-stimulating factors Expired GB755644A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US755644XA 1953-02-17 1953-02-17

Publications (1)

Publication Number Publication Date
GB755644A true GB755644A (en) 1956-08-22

Family

ID=22126579

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4184/54A Expired GB755644A (en) 1953-02-17 1954-02-12 Improvements in or relating to processes for the recovery of growth-stimulating factors

Country Status (1)

Country Link
GB (1) GB755644A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1212826B (en) * 1960-02-24 1966-03-17 Bierhefe Verarbeitungsgesellsc Feed additive and process for its manufacture

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1212826B (en) * 1960-02-24 1966-03-17 Bierhefe Verarbeitungsgesellsc Feed additive and process for its manufacture

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