GB709373A - 6-methyl-8-hydroxy-ergoline - Google Patents

6-methyl-8-hydroxy-ergoline

Info

Publication number
GB709373A
GB709373A GB25010/51A GB2501051A GB709373A GB 709373 A GB709373 A GB 709373A GB 25010/51 A GB25010/51 A GB 25010/51A GB 2501051 A GB2501051 A GB 2501051A GB 709373 A GB709373 A GB 709373A
Authority
GB
United Kingdom
Prior art keywords
methyl
hydroxy
ergoline
butanol
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB25010/51A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of GB709373A publication Critical patent/GB709373A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The invention comprises 6-methyl-8-hydroxyergoline of the formula <FORM:0709373/IV (b)/1> and a process for the preparation thereof by treating 31-amino-1-methyl-3-hydroxy-1,2,3,4-tetrahydro - 5,6 - benzoquinoline - 7 - carboxylic acid lactam of the formula <FORM:0709373/IV (b)/2> with a reducing agent capable of converting a C=O group to a CH group. The process may be carried out with an alkali metal and an alcohol, e.g. n-butanol. In the example, the process is carried out with n-butanol and sodium. The 8-acetyl derivative of 6-methyl-8-hydroxy-ergoline is also referred to. Specification 705,436 is referred to.
GB25010/51A 1950-10-26 1951-10-25 6-methyl-8-hydroxy-ergoline Expired GB709373A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH709373X 1950-10-26

Publications (1)

Publication Number Publication Date
GB709373A true GB709373A (en) 1954-05-19

Family

ID=4530644

Family Applications (1)

Application Number Title Priority Date Filing Date
GB25010/51A Expired GB709373A (en) 1950-10-26 1951-10-25 6-methyl-8-hydroxy-ergoline

Country Status (1)

Country Link
GB (1) GB709373A (en)

Similar Documents

Publication Publication Date Title
FR1179825A (en) Process for the preparation of alpha, beta-di- (arylazolyl) -ethylene derivatives
GB709373A (en) 6-methyl-8-hydroxy-ergoline
GB733650A (en) Isophorone and its homologues
GB999255A (en) Novel unsaturated alcohols and a process for the preparation thereof
FR968179A (en) Process for preparing isopropyl alcohol
GB887012A (en) Process for the preparation of 18ª--glycyrrhetinic acid
GB937598A (en) Process for the production of reserpic acid diesters
GB888418A (en) Improvements in or relating to reserpine and its derivatives
GB888408A (en) Indoles and their preparation
GB685747A (en) Cyclohexen-(1)-yl-ethylamine and process for the manufacture thereof
GB672357A (en) Method of manufacture of a bis-coumarinyl derivative
GB563173A (en) Improvements in plaster of paris bandages
GB711424A (en) Treatment of delta-tetrahydrobenzaldehyde
FR970602A (en) Process for preparing ethyl alcohol
FR1302352A (en) Process for preparing aqueous solutions of azulene, color stable
GB750916A (en) Process for the preparation of the dihydrostreptomycin salt of levulinic acid isonicotinylhydrazone
GB730628A (en) Improvements in or relating to new organo-mercury compounds and a process for preparing the same
GB952708A (en) New camphorated derivatives of 2-aminothiazoline and their process of preparation
GB758839A (en) Improvements in and relating to the preparation of adhesives
GB850386A (en) Cyclopentanophenanthrene derivatives and processes for the production thereof
GB815341A (en) 19-nor-delta-4-androsten-3-one-17-beta-ol hexahydro-benzoate and method for manufacturing same
GB937616A (en) A process for the manufacture of 16-halomethyl-steroids and new 16-halomethyl-steroids
GB753525A (en) Penicillin compounds with benzimidazoles
GB833799A (en) Thiocolchicine derivatives and their preparation
GB965929A (en) Novel steroid compounds and their production