GB660145A - Fermentation process - Google Patents

Fermentation process

Info

Publication number
GB660145A
GB660145A GB2865648A GB2865648A GB660145A GB 660145 A GB660145 A GB 660145A GB 2865648 A GB2865648 A GB 2865648A GB 2865648 A GB2865648 A GB 2865648A GB 660145 A GB660145 A GB 660145A
Authority
GB
United Kingdom
Prior art keywords
streptomycin
temperature
tubes
culture medium
producing organism
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2865648A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
HERBERT WILLIAM ASHTON
Distillers Co Yeast Ltd
Distillers Co Ltd
Original Assignee
HERBERT WILLIAM ASHTON
Distillers Co Yeast Ltd
Distillers Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by HERBERT WILLIAM ASHTON, Distillers Co Yeast Ltd, Distillers Co Ltd filed Critical HERBERT WILLIAM ASHTON
Priority to GB2865648A priority Critical patent/GB660145A/en
Publication of GB660145A publication Critical patent/GB660145A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C12M41/18—Heat exchange systems, e.g. heat jackets or outer envelopes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/18—External loop; Means for reintroduction of fermented biomass or liquid percolate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/46—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin
    • C12P19/54—Preparation of O-glycosides, e.g. glucosides having an oxygen atom of the saccharide radical bound to a cyclohexyl radical, e.g. kasugamycin the cyclohexyl radical being bound directly to a nitrogen atom of two or more radicals, e.g. streptomycin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Analytical Chemistry (AREA)
  • Thermal Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Physics & Mathematics (AREA)

Abstract

In the production of streptomycin by the aerobic fermentation of a culture medium with a streptomycin-producing organism under conditions of submerged growth, the temperature is controlled by circulating a portion of the wash through a heat exchanger (preferably comprising a set of tubes in parallel contained in a jacket through which heating or cooling media may be passed, the dimensions of the tubes and the circulating system being desirably such that the rate of circulation of the liquid is sufficient to prevent the settling of mycelium therein, e.g. at least 0.7 feet per second). Advantageously the culture medium is first heated to a temperature and for a time sufficient to sterilize it, then cooled to the fermentation temperature and inoculated thereat with the streptomycin-producing organism, e.g. Streptomyces grisens. A suitable arrangement of apparatus is described with drawings.
GB2865648A 1948-11-04 1948-11-04 Fermentation process Expired GB660145A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2865648A GB660145A (en) 1948-11-04 1948-11-04 Fermentation process

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2865648A GB660145A (en) 1948-11-04 1948-11-04 Fermentation process

Publications (1)

Publication Number Publication Date
GB660145A true GB660145A (en) 1951-10-31

Family

ID=10279043

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2865648A Expired GB660145A (en) 1948-11-04 1948-11-04 Fermentation process

Country Status (1)

Country Link
GB (1) GB660145A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL79006C (en) * 1950-03-06 1955-09-15 Eugen Georg Stich

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL79006C (en) * 1950-03-06 1955-09-15 Eugen Georg Stich

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