GB704872A - Improvements in methods and apparatus for the cultivation of microorganisms - Google Patents

Improvements in methods and apparatus for the cultivation of microorganisms

Info

Publication number
GB704872A
GB704872A GB29912/50A GB2991250A GB704872A GB 704872 A GB704872 A GB 704872A GB 29912/50 A GB29912/50 A GB 29912/50A GB 2991250 A GB2991250 A GB 2991250A GB 704872 A GB704872 A GB 704872A
Authority
GB
United Kingdom
Prior art keywords
drum
culture
stirring
dec
ribs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB29912/50A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LE BACTOGENE SOC
Original Assignee
LE BACTOGENE SOC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LE BACTOGENE SOC filed Critical LE BACTOGENE SOC
Publication of GB704872A publication Critical patent/GB704872A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/10—Rotating vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/24—Draft tube
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/14—Pressurized fluid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/04—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by injection or suction, e.g. using pipettes, syringes, needles
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

704,872. Stirring appliances. SOC. LE BACTOGENE. Dec. 6, 1950 [Dec. 21, 1949; July 13, 1950; Nov. 9, 1950], No. 29912/50. Class 86 [Also in Group VI] An apparatus for the culture of microorganisms (see Group VI) comprises in combination, a drum of substantially horizontal axis to contain the culture in treatment, means for continually adding fresh nutrient into the drum and means for continuously removing culture from the drum by means of continuously stirring the culture in the drum. As shown in Fig. 1 a rotary horizontal drum 1 is provided with an interior spiral rib 10, an entry pipe 12 through which the medium is pumped by a pump 50 and a siphon 13 for withdrawing the produced culture and an entry 16 for inoculating the culture. Heating at constant temperature is obtained either by placing the drum in a thermostatic vessel or by disposing electric resistances on the outer surface or inside of the drum, a regulator 11 dipping in the culture being provided for adjusting the thermostatic system. In a modification of the apparatus shown in Fig. 2 the drum 1 is provided with co-axial cylinders which are provided with continuous or perforated surfaces 22, 23 and which may be secured by braces 24, 25, 26, 27 or which may turn independently of the drum possibly in the opposite directions being driven through mechanism such as diagrammatically shown by references 101-104. The cylinders may also be provided with helical or other ribs analogous to the ribs 10 in Fig. 1 to ensure thorough stirring. The drum 1 may be stationary with only the inner cylinder rotary. High bacteriological sterility is ensured by providing sterilizing devices such as ultra-violet ray tubes round a cylindrical element 160 rigid with the closure plate 9 so that air entering will be sterilized.
GB29912/50A 1949-12-21 1950-12-06 Improvements in methods and apparatus for the cultivation of microorganisms Expired GB704872A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR704872X 1949-12-21

Publications (1)

Publication Number Publication Date
GB704872A true GB704872A (en) 1954-03-03

Family

ID=9066847

Family Applications (1)

Application Number Title Priority Date Filing Date
GB29912/50A Expired GB704872A (en) 1949-12-21 1950-12-06 Improvements in methods and apparatus for the cultivation of microorganisms

Country Status (1)

Country Link
GB (1) GB704872A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2715795A (en) * 1954-06-22 1955-08-23 Basic Res Corp Microorganism culture method and apparatus
US2822319A (en) * 1954-08-17 1958-02-04 Monod Jacques Methods for the cultivation of micro-organisms
US2996429A (en) * 1959-02-12 1961-08-15 Nat Toxicological Lab Inc Method and apparatus for growing living tissue
DE1228579B (en) * 1957-08-03 1966-11-17 Distillers Co Yeast Ltd Continuous process for growing yeast
WO1989000612A1 (en) * 1987-07-10 1989-01-26 Hallberg Rolf O A device for providing a continuous biological decomposition of minerals and concentrates thereof
CN112716011A (en) * 2020-12-11 2021-04-30 轩苗苗 Waste rapeseed meal recycling pretreatment device

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2715795A (en) * 1954-06-22 1955-08-23 Basic Res Corp Microorganism culture method and apparatus
US2822319A (en) * 1954-08-17 1958-02-04 Monod Jacques Methods for the cultivation of micro-organisms
DE1228579B (en) * 1957-08-03 1966-11-17 Distillers Co Yeast Ltd Continuous process for growing yeast
US2996429A (en) * 1959-02-12 1961-08-15 Nat Toxicological Lab Inc Method and apparatus for growing living tissue
WO1989000612A1 (en) * 1987-07-10 1989-01-26 Hallberg Rolf O A device for providing a continuous biological decomposition of minerals and concentrates thereof
CN112716011A (en) * 2020-12-11 2021-04-30 轩苗苗 Waste rapeseed meal recycling pretreatment device

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