GB642385A - Improvements in therapeutic products - Google Patents

Improvements in therapeutic products

Info

Publication number
GB642385A
GB642385A GB31220/47A GB3122047A GB642385A GB 642385 A GB642385 A GB 642385A GB 31220/47 A GB31220/47 A GB 31220/47A GB 3122047 A GB3122047 A GB 3122047A GB 642385 A GB642385 A GB 642385A
Authority
GB
United Kingdom
Prior art keywords
oil
water
injectible
vegetable
per cent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB31220/47A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Wyeth Inc
Original Assignee
Wyeth LLC
Wyeth Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth LLC, Wyeth Inc filed Critical Wyeth LLC
Publication of GB642385A publication Critical patent/GB642385A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)

Abstract

Injectible medicines with prolonged activity are prepared by forming a non-aqueous suspension in a vegetable oil of the dry therapeutic product and a hydrophilic substance consisting of a poly-saccharide or a protein substance containing less than one per cent of water but which on contact with water will form a gel, the vegetable oil having an affinity for body tissue and containing less than one per cent of water and the solid ingredients having a particle size small enough to pass through the standard size needle. Specified therapeutic products are penicillins, streptomycins, bactiracin, eumycin, subtilin, insulins, hormones, vasoconstrictors, and vitamins. The preferred hydrophilic substance is pectin but cellulose compounds, sodium alginate, and gelatin may be used. Specified vegetable oils are peanut oil, sesame oil, cotton seed oil, corn oil and soya bean oil. The Specification as open to inspection under Sect. 91 describes also the employment of an injectible glycol such as propylene glycol instead of the vegetable oil. This subject-matter does not appear in the Specification as accepted.
GB31220/47A 1947-06-03 1947-11-25 Improvements in therapeutic products Expired GB642385A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US642385XA 1947-06-03 1947-06-03

Publications (1)

Publication Number Publication Date
GB642385A true GB642385A (en) 1950-08-30

Family

ID=22054523

Family Applications (1)

Application Number Title Priority Date Filing Date
GB31220/47A Expired GB642385A (en) 1947-06-03 1947-11-25 Improvements in therapeutic products

Country Status (1)

Country Link
GB (1) GB642385A (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0140255A2 (en) * 1983-10-14 1985-05-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release injections
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
US4849141A (en) * 1985-12-27 1989-07-18 Sumitomo Pharmaceuticals Company, Limited Method for producing sustained release formulation
US4855134A (en) * 1983-10-14 1989-08-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release preparation
US5385738A (en) * 1983-10-14 1995-01-31 Sumitomo Pharmaceuticals Company, Ltd. Sustained-release injection
GB2398496A (en) * 2003-02-20 2004-08-25 Reckitt Benckiser Healthcare Suspensions of water-swellable polymer particles which are substantially water-free or contain insufficient water to fully swell the particles

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0140255A2 (en) * 1983-10-14 1985-05-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release injections
EP0140255A3 (en) * 1983-10-14 1985-10-30 Sumitomo Chemical Company, Limited Sustained-release injections
US4774091A (en) * 1983-10-14 1988-09-27 Sumitomo Pharmaceuticals Company, Ltd. Long-term sustained-release preparation
US4855134A (en) * 1983-10-14 1989-08-08 Sumitomo Pharmaceuticals Company, Limited Sustained-release preparation
US5021241A (en) * 1983-10-14 1991-06-04 Sumitomo Pharmaceuticals Company, Limited Long-term sustained-release preparation
US5081156A (en) * 1983-10-14 1992-01-14 Sumitomo Pharmaceuticals Company, Ltd. Sustained-release preparation
US5385738A (en) * 1983-10-14 1995-01-31 Sumitomo Pharmaceuticals Company, Ltd. Sustained-release injection
US4849141A (en) * 1985-12-27 1989-07-18 Sumitomo Pharmaceuticals Company, Limited Method for producing sustained release formulation
GB2398496A (en) * 2003-02-20 2004-08-25 Reckitt Benckiser Healthcare Suspensions of water-swellable polymer particles which are substantially water-free or contain insufficient water to fully swell the particles

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