GB934686A - Therapeutic preparations containing sitosterol - Google Patents

Therapeutic preparations containing sitosterol

Info

Publication number
GB934686A
GB934686A GB804162A GB804162A GB934686A GB 934686 A GB934686 A GB 934686A GB 804162 A GB804162 A GB 804162A GB 804162 A GB804162 A GB 804162A GB 934686 A GB934686 A GB 934686A
Authority
GB
United Kingdom
Prior art keywords
sitosterol
microns
particle size
sugar
therapeutic preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB804162A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
C F Boehringer & Soehne GmbH
Roche Diagnostics GmbH
Original Assignee
C F Boehringer & Soehne GmbH
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C F Boehringer & Soehne GmbH, Boehringer Mannheim GmbH filed Critical C F Boehringer & Soehne GmbH
Publication of GB934686A publication Critical patent/GB934686A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to therapeutic preparations comprising sitosterol with a particle size of less than 30 microns. a crystalline sugar as filler, and 1 to 4% gelatine or 0.1 to 2% methyl cellulose, based on the content of sitosterol. Coarsely-powdered sitosterol is ground with the sugar to a particle size of less than 30 microns and the ground material is mixed with water containing the gelatine or methyl cellulose. A particle size of 1-10 microns is preferred and the grinding may be done in a disc mill. Flavouring and preservative agents may be added. The sugar may be sucrose or lactose. The preparation may be administered orally.
GB804162A 1961-04-05 1962-03-01 Therapeutic preparations containing sitosterol Expired GB934686A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEB62020A DE1131845B (en) 1961-04-05 1961-04-05 Process for the production of therapeutically valuable sitosterol preparations
DEB65853A DE1139236B (en) 1961-04-05 1962-02-08 Process for the production of therapeutically valuable stitosterol preparations

Publications (1)

Publication Number Publication Date
GB934686A true GB934686A (en) 1963-08-21

Family

ID=25965908

Family Applications (1)

Application Number Title Priority Date Filing Date
GB804162A Expired GB934686A (en) 1961-04-05 1962-03-01 Therapeutic preparations containing sitosterol

Country Status (6)

Country Link
BE (1) BE615975A (en)
BR (1) BR6237169D0 (en)
DE (2) DE1131845B (en)
GB (1) GB934686A (en)
LU (1) LU41386A1 (en)
NL (2) NL142069B (en)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135337A2 (en) * 1983-08-13 1985-03-27 Bellex Corporation Preventive and curative preparation for thrombosis
WO1998013023A1 (en) * 1996-09-27 1998-04-02 Suomen Sokeri Oy A product, a method for its production, and its use
WO1998058554A1 (en) * 1997-06-13 1998-12-30 Danisco Finland Oy Product, method for its manufacture, and its use
WO2000041491A2 (en) * 1999-01-15 2000-07-20 Nutrahealth Ltd (Uk) Modified food products and beverages, and additives for food and beverages
WO2000045648A1 (en) * 1999-02-03 2000-08-10 Forbes Medi-Tech Inc. Method of preparing microparticles of phytosterols or phytostanols
EP1695634A1 (en) * 2005-02-24 2006-08-30 Cognis IP Management GmbH Sugar containing solid sterol dispersions
US7335389B2 (en) 2002-06-12 2008-02-26 The Coca-Cola Company Beverages containing plant sterols
US7732000B2 (en) * 2002-06-20 2010-06-08 General Mills, Inc. Food intermediate having sequestered phytosteryl esters in a polysaccharide matrix
EP1197153B2 (en) † 1997-08-22 2011-03-23 Unilever N.V. Aqueous dispersions or suspensions

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3829643A1 (en) * 1988-09-01 1990-03-15 Roecar Holdings Nv PHYTO AND ZOOSTEROLS AND THEIR DERIVATIVES WITH IMPROVED WATER SOLUBILITY

Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0135337A3 (en) * 1983-08-13 1985-07-31 Bellex Corporation Preventive and curative preparation for thrombosis and method of treating the same
US4582826A (en) * 1983-08-13 1986-04-15 Bellex Corporation Method of treating thrombosis
EP0135337A2 (en) * 1983-08-13 1985-03-27 Bellex Corporation Preventive and curative preparation for thrombosis
AU730432B2 (en) * 1996-09-27 2001-03-08 Suomen Sokeri Oy A product, a method for its production, and its use
WO1998013023A1 (en) * 1996-09-27 1998-04-02 Suomen Sokeri Oy A product, a method for its production, and its use
US6129944A (en) * 1996-09-27 2000-10-10 Suomen Sokeri Oy Product, a method for its production, and its use
WO1998058554A1 (en) * 1997-06-13 1998-12-30 Danisco Finland Oy Product, method for its manufacture, and its use
EP0897671B2 (en) † 1997-08-22 2011-07-06 Unilever N.V. Aqueous dispersions or suspensions
EP1197153B2 (en) † 1997-08-22 2011-03-23 Unilever N.V. Aqueous dispersions or suspensions
WO2000041491A3 (en) * 1999-01-15 2000-12-07 Nutrahealth Ltd Modified food products and beverages, and additives for food and beverages
WO2000041491A2 (en) * 1999-01-15 2000-07-20 Nutrahealth Ltd (Uk) Modified food products and beverages, and additives for food and beverages
WO2000045648A1 (en) * 1999-02-03 2000-08-10 Forbes Medi-Tech Inc. Method of preparing microparticles of phytosterols or phytostanols
US7335389B2 (en) 2002-06-12 2008-02-26 The Coca-Cola Company Beverages containing plant sterols
US7732000B2 (en) * 2002-06-20 2010-06-08 General Mills, Inc. Food intermediate having sequestered phytosteryl esters in a polysaccharide matrix
US8168248B2 (en) 2002-06-20 2012-05-01 General Mills, Inc. Food intermediate having sequestered phytosteryl esters in a polysaccharide matrix
EP1695634A1 (en) * 2005-02-24 2006-08-30 Cognis IP Management GmbH Sugar containing solid sterol dispersions
US8029845B2 (en) 2005-02-24 2011-10-04 Cognis Ip Management Gmbh Compositions of sugar-containing sterol solids dispersions

Also Published As

Publication number Publication date
BR6237169D0 (en) 1973-05-24
NL142069B (en) 1974-05-15
BE615975A (en) 1962-10-04
DE1139236B (en) 1962-11-08
NL276700A (en)
LU41386A1 (en) 1962-05-15
DE1131845B (en) 1962-06-20

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