GB615404A - A process for the preparation of unsaturated derivatives of 2-methyl-2-hydroxy-3-halogen-teterahydrofurane and for their conversion to vitamin b and the like - Google Patents

A process for the preparation of unsaturated derivatives of 2-methyl-2-hydroxy-3-halogen-teterahydrofurane and for their conversion to vitamin b and the like

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Publication number
GB615404A
GB615404A GB12641/41A GB1264141A GB615404A GB 615404 A GB615404 A GB 615404A GB 12641/41 A GB12641/41 A GB 12641/41A GB 1264141 A GB1264141 A GB 1264141A GB 615404 A GB615404 A GB 615404A
Authority
GB
United Kingdom
Prior art keywords
methyl
hydroxy
halogen
vitamin
unsaturated derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB12641/41A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chinoin Private Co Ltd
Original Assignee
Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt filed Critical Chinoin Gyogyszer es Vegyeszeti Termekek Gyara Zrt
Publication of GB615404A publication Critical patent/GB615404A/en
Expired legal-status Critical Current

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Unsaturated derivatives of 2 - methyl - 2 - hydroxy-3-halogen-tetrahydrofuranes containing one molecule of water less than the parent compound are prepared and converted to Vitamin B1 by a process which comprises subjecting 2-methyl-2,3-dihalogen-tetrahydrofuranes or reaction mixtures containing these compounds to the action of reagents which are capable of splitting of halide acid, e.g. pyridine and, if desired, subjecting to the action of 2-alkyl-4-amino-5-(thioformanidoalkyl)-pyrimidine to produce Vitamin B1. The unsaturated derivatives of 2-methyl-2-hydroxy-3-halogen-tetrahydrofuranes containing one molecule of water less than the parent compound may also be prepared by treating aceto-chloro-propyl alcohol with phosphorous halogenides and treating the reaction mixture with agents capable of splitting off a halide acid. Detailed examples are given. Specification 609,803 is referred to.
GB12641/41A 1940-05-27 1941-09-30 A process for the preparation of unsaturated derivatives of 2-methyl-2-hydroxy-3-halogen-teterahydrofurane and for their conversion to vitamin b and the like Expired GB615404A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU615404X 1940-05-27

Publications (1)

Publication Number Publication Date
GB615404A true GB615404A (en) 1949-01-06

Family

ID=10979760

Family Applications (1)

Application Number Title Priority Date Filing Date
GB12641/41A Expired GB615404A (en) 1940-05-27 1941-09-30 A process for the preparation of unsaturated derivatives of 2-methyl-2-hydroxy-3-halogen-teterahydrofurane and for their conversion to vitamin b and the like

Country Status (1)

Country Link
GB (1) GB615404A (en)

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