GB611098A - The manufacture of bile acid derivatives - Google Patents
The manufacture of bile acid derivativesInfo
- Publication number
- GB611098A GB611098A GB2652246A GB2652246A GB611098A GB 611098 A GB611098 A GB 611098A GB 2652246 A GB2652246 A GB 2652246A GB 2652246 A GB2652246 A GB 2652246A GB 611098 A GB611098 A GB 611098A
- Authority
- GB
- United Kingdom
- Prior art keywords
- bile acid
- acid derivatives
- manufacture
- keto
- reaction
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Steroid Compounds (AREA)
Abstract
Bile acid derivatives of the general formula R-COO(CH2)nNR1R2 where R-COOH represents a keto-bile acid (e.g. dehydrodesoxy- or dehydro-cholic acid, n is a small integer and R1 and R2 are alkyl groups or together form the residue of a heterocyclic group which include the N-atom in a ring are obtained by esterifying a keto bile acid with a dialkylamino (including piperidino and morpholino) alkyl alcohol or halide while removing the water or hydrogen halide formed from the reaction, e.g. by distillation or by carrying the reaction in the presence of a basic substance. Detailed examples are given.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2652246A GB611098A (en) | 1946-09-04 | 1946-09-04 | The manufacture of bile acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2652246A GB611098A (en) | 1946-09-04 | 1946-09-04 | The manufacture of bile acid derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
GB611098A true GB611098A (en) | 1948-10-25 |
Family
ID=10244945
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2652246A Expired GB611098A (en) | 1946-09-04 | 1946-09-04 | The manufacture of bile acid derivatives |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB611098A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2935525A (en) * | 1956-08-13 | 1960-05-03 | Abbott Lab | Esterification of organic acids |
-
1946
- 1946-09-04 GB GB2652246A patent/GB611098A/en not_active Expired
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2935525A (en) * | 1956-08-13 | 1960-05-03 | Abbott Lab | Esterification of organic acids |
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