GB610198A - The manufacture of ether-esters of organic hydroxy-acids - Google Patents

The manufacture of ether-esters of organic hydroxy-acids

Info

Publication number
GB610198A
GB610198A GB990446A GB990446A GB610198A GB 610198 A GB610198 A GB 610198A GB 990446 A GB990446 A GB 990446A GB 990446 A GB990446 A GB 990446A GB 610198 A GB610198 A GB 610198A
Authority
GB
United Kingdom
Prior art keywords
group
piperidinoalkyl
alkyl
benzilate
dialkylaminoalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB990446A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MARIANNE KOENIGSTEIN
Roche Products Ltd
Original Assignee
MARIANNE KOENIGSTEIN
Roche Products Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NL62989D priority Critical patent/NL62989C/xx
Application filed by MARIANNE KOENIGSTEIN, Roche Products Ltd filed Critical MARIANNE KOENIGSTEIN
Priority to GB990446A priority patent/GB610198A/en
Publication of GB610198A publication Critical patent/GB610198A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Mandelic acid derivatives of the general formula <FORM:0610198/IV(b)/1> (in which R is a phenyl or substituted phenyl group, R1 is hydrogen, an alkyl, aralkyl, aryl, alkaryl or a homocyclic group, R2 is a dialkylamino-alkyl or piperidinoalkyl group, R3 and R4 are alkyl groups or together form a polymethylene ring, and n is an integer not greater than 4) are prepared by reacting a dialkylamino-alkyl or piperidinoalkyl halide with an alkali metal derivative of an ester of an a -hydroxy carboxylic acid of the formula <FORM:0610198/IV(b)/2> (in which X is hydrogen or the dialkylaminoalkyl or piperidinoalkyl group, and Y is the dialkylaminoalkyl or piperidinoalkyl group or hydrogen, respectively). In a modification, an alkali metal derivative of an ester of the general formula <FORM:0610198/IV(b)/3> (in which Y1 is an alkyl group) is hydrolyzed with an alkali metal hydroxide and the salt so formed is reacted with a dialkylaminoalkyl or piperidinoalkyl halide. Examples are given of the preparation of (1) and (4) the b -dimethylaminoethyl ether of diethylaminoethyl benzilate; (2) the b -dimethylaminoethyl ether of b -dimethylaminoethyl benzilate, and (3) the b -dimethylaminoethyl ether of b -piperidinoethyl benzilate. Specification 558,653 is referred to.
GB990446A 1946-03-30 1946-03-30 The manufacture of ether-esters of organic hydroxy-acids Expired GB610198A (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NL62989D NL62989C (en) 1946-03-30
GB990446A GB610198A (en) 1946-03-30 1946-03-30 The manufacture of ether-esters of organic hydroxy-acids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB990446A GB610198A (en) 1946-03-30 1946-03-30 The manufacture of ether-esters of organic hydroxy-acids

Publications (1)

Publication Number Publication Date
GB610198A true GB610198A (en) 1948-10-12

Family

ID=9880942

Family Applications (1)

Application Number Title Priority Date Filing Date
GB990446A Expired GB610198A (en) 1946-03-30 1946-03-30 The manufacture of ether-esters of organic hydroxy-acids

Country Status (2)

Country Link
GB (1) GB610198A (en)
NL (1) NL62989C (en)

Also Published As

Publication number Publication date
NL62989C (en)

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