GB606480A - Improvements in and relating to a method for the production of esters of dioles and trioles of cyclopentane-polyhydro-phenanthrene series - Google Patents

Improvements in and relating to a method for the production of esters of dioles and trioles of cyclopentane-polyhydro-phenanthrene series

Info

Publication number
GB606480A
GB606480A GB2261/46A GB226146A GB606480A GB 606480 A GB606480 A GB 606480A GB 2261/46 A GB2261/46 A GB 2261/46A GB 226146 A GB226146 A GB 226146A GB 606480 A GB606480 A GB 606480A
Authority
GB
United Kingdom
Prior art keywords
trioles
dioles
esters
polyhydro
cyclopentane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB2261/46A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Leo Pharma AS
Original Assignee
Leo Pharmaceutical Products Ltd AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharmaceutical Products Ltd AS filed Critical Leo Pharmaceutical Products Ltd AS
Publication of GB606480A publication Critical patent/GB606480A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Abstract

Esters of dioles and trioles of the cyclopentanopolyhydrophenanthrene series, e.g. oestradiole, oestratiole, androstandiole and androstindiole, are produced by the said dioles and trioles being first reacted with Grignard compounds, after which the halogen-magnesium compounds produced are treated with anhydrides or halogenides of acids with 3 or more carbon atoms in the molecule. In examples (1) a solution of oestradiole and magnesium ethyl bromide in ether is treated with propionic acid anhydride to produce oestradiole propionate.
GB2261/46A 1942-01-29 1946-01-23 Improvements in and relating to a method for the production of esters of dioles and trioles of cyclopentane-polyhydro-phenanthrene series Expired GB606480A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK606480X 1942-01-29

Publications (1)

Publication Number Publication Date
GB606480A true GB606480A (en) 1948-08-13

Family

ID=8151619

Family Applications (1)

Application Number Title Priority Date Filing Date
GB2261/46A Expired GB606480A (en) 1942-01-29 1946-01-23 Improvements in and relating to a method for the production of esters of dioles and trioles of cyclopentane-polyhydro-phenanthrene series

Country Status (1)

Country Link
GB (1) GB606480A (en)

Similar Documents

Publication Publication Date Title
GB606480A (en) Improvements in and relating to a method for the production of esters of dioles and trioles of cyclopentane-polyhydro-phenanthrene series
GB883769A (en) 3ª-:16ª-:17ª--trihydroxy steroids
GB428223A (en) Improvements in or relating to the production of esters of unsaturated monocarboxylic aliphatic acids
GB570271A (en) Improvements in or relating to the manufacture of carboxylic acid anhydrides
GB845442A (en) Manufacture of steroid compounds
GB598798A (en) A process for the manufacture of 3.4-di-(p-hydroxy-phenyl)-hexadiene-2.4
GB560081A (en) A process for the manufacture of new unsaturated alcohols
GB922877A (en) New derivatives of 13-methylcyclopentanopolyhydrophenanthrene and methods for the production thereof
GB865316A (en) Improvements in or relating to steroids and the manufacture thereof
GB459207A (en) Process for the manufacture of laevo-ascorbic acid
GB748600A (en) Process for the production of the methobromide of a basic ester
GB634741A (en) Preparation of compounds of the cyclopentanodimethylpolyhydrophenanthrene series
GB963964A (en) Improvements in or relating to the bromination of hecogenin and esters thereof
GB908674A (en) Preparation of 17ª--acyloxy-6ª--methyl-16-methylenepregn-4-ene-3,20-diones
GB1077393A (en) New steroids
GB736242A (en) Steroids
GB600865A (en) Improvements in or relating to a process of preparing butyrolactones
GB431833A (en) Process for the production of pregnanolones
GB593013A (en) Improvements in and relating to the production of dl-n-formyl-isopropylidene-penicillamine l-brucine salt
GB744087A (en) Purification of acids
GB1036418A (en) 19-alkyl-steroids and process for their production
GB463456A (en) Improvements in the manufacture and production of compounds of the azaphenanthrene series
GB447756A (en) Improvements relating to the production of acid anhydrides
GB887011A (en) Glycyrrhetinic acid derivatives
GB922652A (en) Novel d-homo steroid derivatives and processes for their preparation