GB736242A - Steroids - Google Patents

Steroids

Info

Publication number
GB736242A
GB736242A GB5011/53A GB501153A GB736242A GB 736242 A GB736242 A GB 736242A GB 5011/53 A GB5011/53 A GB 5011/53A GB 501153 A GB501153 A GB 501153A GB 736242 A GB736242 A GB 736242A
Authority
GB
United Kingdom
Prior art keywords
hydroxy
acid
testosterone
hydroxytesterone
normethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB5011/53A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of GB736242A publication Critical patent/GB736242A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

The invention comprises 17-carboxylic acid esters of 14(a )-hydroxytestosterone or 14(a )-hydroxy - 10 - normethyltestosterone and the preparation thereof by treating 14(a )-hydroxytesterone or 14(a ) - hydroxy - 10 - normethyl testosterone with an acylating agent, e.g. an acid, acid anhydride or acid halide. The reaction may be effected in a solvent such as pyridine, benzene, toluene or ether from 0 DEG C. to the b.p. of the reaction mixture. Examples disclose the use of acetic anhydride, formic acid, propionic anhydride and b -cyclopentylpropionyl chloride and benzoyl chloride as acylating agents. Other esters of aliphatic and carbocyclic acids containing up to eight carbon atoms may be produced. Specification 734,797 is referred to.ALSO:An absorption base useful in pharmacy and cosmetology comprises petrolatum stearyl alcohol, and a 17-carboxylic ester of 14(a )-hydroxy-testosterone or 14(a )-hydroxy-10-normethyl-testosterone, e.g. 14(a )-hydroxytesterone-17-acetate. Specification 734,797, [Group IV (b)], is referred to.
GB5011/53A 1952-02-23 1953-02-23 Steroids Expired GB736242A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US736242XA 1952-02-23 1952-02-23

Publications (1)

Publication Number Publication Date
GB736242A true GB736242A (en) 1955-09-07

Family

ID=22114807

Family Applications (1)

Application Number Title Priority Date Filing Date
GB5011/53A Expired GB736242A (en) 1952-02-23 1953-02-23 Steroids

Country Status (1)

Country Link
GB (1) GB736242A (en)

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