GB459207A - Process for the manufacture of laevo-ascorbic acid - Google Patents
Process for the manufacture of laevo-ascorbic acidInfo
- Publication number
- GB459207A GB459207A GB16843/36A GB1684336A GB459207A GB 459207 A GB459207 A GB 459207A GB 16843/36 A GB16843/36 A GB 16843/36A GB 1684336 A GB1684336 A GB 1684336A GB 459207 A GB459207 A GB 459207A
- Authority
- GB
- United Kingdom
- Prior art keywords
- acid
- keto
- solution
- ascorbic acid
- alcoholic solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/62—Three oxygen atoms, e.g. ascorbic acid
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Furan Compounds (AREA)
Abstract
The process described in the parent Specification which comprises the manufacture of l vo-ascorbic acid by heating in an acid solution 2-keto l vo-gulonic acid or its derivatives which are easily split with acids, is modified in that the reaction is carried out in alcoholic solution. In examples: (1) hydrogen chloride is passed into an alcoholic solution of 2-keto-l vo-gulonic acid methyl ester, the solution boiled for four hours and then evaporated in vacuo. The residue is soaked with butyl alcohol, washed with acetic acid and ether, and finally recrystallized from methanol to yield pure ascorbic acid; (2) diacetone - 2 - keto - l vo - gulonic acid - monohydrate is boiled in a 3 per cent absolute alcoholic solution of hydrochloric acid, and the product worked up as in example (1); (3) 2-keto-l vo-gulonic acid is treated as described in example (2). Specification 428,814 is referred to.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH459207X | 1935-06-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB459207A true GB459207A (en) | 1937-01-04 |
Family
ID=4515678
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB16843/36A Expired GB459207A (en) | 1935-06-18 | 1936-06-17 | Process for the manufacture of laevo-ascorbic acid |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB459207A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2491933A (en) * | 1943-08-03 | 1949-12-20 | Naarden Chem Fab | Process for the manufacture of esters of monomethylene ethers of 1 keto-2 gulonic acid |
| CN111018815A (en) * | 2019-12-29 | 2020-04-17 | 安徽丰原发酵技术工程研究有限公司 | Method for preparing vitamin C by increasing concentration of hydrochloric acid through solvent extraction |
-
1936
- 1936-06-17 GB GB16843/36A patent/GB459207A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2491933A (en) * | 1943-08-03 | 1949-12-20 | Naarden Chem Fab | Process for the manufacture of esters of monomethylene ethers of 1 keto-2 gulonic acid |
| CN111018815A (en) * | 2019-12-29 | 2020-04-17 | 安徽丰原发酵技术工程研究有限公司 | Method for preparing vitamin C by increasing concentration of hydrochloric acid through solvent extraction |
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