GB606196A - Improvements in and relating to biotin and processes of preparing the same - Google Patents
Improvements in and relating to biotin and processes of preparing the sameInfo
- Publication number
- GB606196A GB606196A GB22789/45A GB2278945A GB606196A GB 606196 A GB606196 A GB 606196A GB 22789/45 A GB22789/45 A GB 22789/45A GB 2278945 A GB2278945 A GB 2278945A GB 606196 A GB606196 A GB 606196A
- Authority
- GB
- United Kingdom
- Prior art keywords
- biotin
- tetrahydrothiophene
- diamino
- trans
- relating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
Biotin, represented by the formula <FORM:0606196/IV(b)/1> is obtained by treating 2-(41-carboxybutyl)-3 : 4-diamino-tetrahydrothiophene as an addition salt thereof with phosgene preferably at a temperature of about 0 DEG C. and in an aqueous alkaline solution, e.g. a solution of an alkalimetal base or an alkali metal salt of a weak acid. Compounds of the above formula are obtained as racemates of stereoisomers by using the corresponding racemic mixture as starting material. In examples, cis-, trans-allo- and trans - epiallo - 2 - (41 - carboxy - butyl) - 3 : 4 - diamino-tetrahydrothiophene acid sulphates are converted into biotin. Specifications 606,188, 606,189, 606,190, 606,191, 606,192, 606,193, 606,194 and 606,195 are referred to.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US606196XA | 1944-09-16 | 1944-09-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
GB606196A true GB606196A (en) | 1948-08-10 |
Family
ID=22030668
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB22789/45A Expired GB606196A (en) | 1944-09-16 | 1945-09-04 | Improvements in and relating to biotin and processes of preparing the same |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB606196A (en) |
-
1945
- 1945-09-04 GB GB22789/45A patent/GB606196A/en not_active Expired
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