GB562216A - Improvements in and relating to the manufacture of water soluble derivatives of 4:4-diaminodiphenylsulphone - Google Patents

Improvements in and relating to the manufacture of water soluble derivatives of 4:4-diaminodiphenylsulphone

Info

Publication number
GB562216A
GB562216A GB1813442A GB1813442A GB562216A GB 562216 A GB562216 A GB 562216A GB 1813442 A GB1813442 A GB 1813442A GB 1813442 A GB1813442 A GB 1813442A GB 562216 A GB562216 A GB 562216A
Authority
GB
United Kingdom
Prior art keywords
aldehyde
sodium
bisulphite
diaminodiphenylsulphone
metabisulphite
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1813442A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wellcome Foundation Ltd
Original Assignee
Wellcome Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Foundation Ltd filed Critical Wellcome Foundation Ltd
Priority to GB1813442A priority Critical patent/GB562216A/en
Publication of GB562216A publication Critical patent/GB562216A/en
Expired legal-status Critical Current

Links

Abstract

Soluble derivatives of 4 : 41-diaminodiphenylsulphone which are of therapeutic value are obtained by reacting this substance with an alkyl aldehyde other than a hydroxy alkyl aldehyde or an alkyl aldehyde containing less than four carbon atoms, an aryl aldehyde or an unsaturated aralkyl aldehyde free from alkyl a -substituents in the presence of sulphurous acids or an aqueous solution of the bisulphite or metabisulphite of an alkali or an alkaline earth metal. The reactants may be mixed in the presence of water, or an aqueous-alcoholic solution containing the sulphone may be treated with sulphur dioxide. In examples, 4 : 41-diaminodiphenylsulphone is reacted with (1) cinnamic aldehyde and sulphurous acid; (2) calcium bisulphite and cinnamic aldehyde; (3) cinnamic acid and sulphurous acid; (4) the strontium salt is prepared from example 3; (5) cinnamic aldehyde and sodium metabisulphite; (6) sodium bisulphite and oenanthol; (7) sodium bisulphite and citral; (8) sodium metabisulphite and vanillin; (9) sodium bisulphite and vanillin; (10) sodium metabisulphite and piperonal; (11) sodium bisulphite and isovaleraldehyde; (12) sodium bisulphite and 2 : 4 - dimethoxybenzaldehyde. Specification 491,265 is referred to.
GB1813442A 1942-12-21 1942-12-21 Improvements in and relating to the manufacture of water soluble derivatives of 4:4-diaminodiphenylsulphone Expired GB562216A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1813442A GB562216A (en) 1942-12-21 1942-12-21 Improvements in and relating to the manufacture of water soluble derivatives of 4:4-diaminodiphenylsulphone

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1813442A GB562216A (en) 1942-12-21 1942-12-21 Improvements in and relating to the manufacture of water soluble derivatives of 4:4-diaminodiphenylsulphone

Publications (1)

Publication Number Publication Date
GB562216A true GB562216A (en) 1944-06-22

Family

ID=10107224

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1813442A Expired GB562216A (en) 1942-12-21 1942-12-21 Improvements in and relating to the manufacture of water soluble derivatives of 4:4-diaminodiphenylsulphone

Country Status (1)

Country Link
GB (1) GB562216A (en)

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