GB855193A - Improvements in or relating to the manufacture of derivatives of nitrofurfuraldehyde - Google Patents

Improvements in or relating to the manufacture of derivatives of nitrofurfuraldehyde

Info

Publication number
GB855193A
GB855193A GB7987/57A GB798757A GB855193A GB 855193 A GB855193 A GB 855193A GB 7987/57 A GB7987/57 A GB 7987/57A GB 798757 A GB798757 A GB 798757A GB 855193 A GB855193 A GB 855193A
Authority
GB
United Kingdom
Prior art keywords
semicarbazone
furfuraldehyde
nitro
arsonophenyl
potassium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7987/57A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Chilcott Pharmaceuticals Inc
Original Assignee
Norwich Pharmacal Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Pharmacal Co filed Critical Norwich Pharmacal Co
Publication of GB855193A publication Critical patent/GB855193A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/66Arsenic compounds
    • C07F9/70Organo-arsenic compounds
    • C07F9/74Aromatic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/70Nitro radicals
    • C07D307/71Nitro radicals attached in position 5
    • C07D307/72Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2
    • C07D307/74Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals
    • C07D307/76Nitro radicals attached in position 5 with hydrocarbon radicals, substituted by nitrogen-containing radicals, attached in position 2 by hydrazino or hydrazono or such substituted radicals having carbonic acyl radicals or their thio or nitrogen analogues directly attached to the hydrazino or hydrazono radical, e.g. semicarbazides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Fodder In General (AREA)

Abstract

The invention comprises 5-nitro-furfuraldehyde-4-(p-arsonophenyl) semicarbazone of formula: <FORM:0855193/IV(b)/1> and its non-toxic water soluble salts, especially the sodium, potassium and ammonium salts. The semicarbazone may be prepared by reacting 4-(p-arsonophenyl)-semicarbazide or a semicarbazone thereof formed by reaction with an aldehyde, with 5-nitro-furfuraldehyde or a functional derivative thereof in the presence of a strong acid. 5-nitro-furfuraldehyde diacetate is specified as a suitable functional derivative, and hydrochloric acid as the strong acid. The water-soluble salts may be prepared by reacting the semicarbazone so prepared with an alkali such as sodium, potassium or ammonium hydroxide. The compounds of the invention may be used for treating coccidiosis in chickens (see Group VI).ALSO:Compositions for treating coccidiosis in fowls comprise 5 - nitro-furfuraldehyde - 4 - (p-arsonophenyl) semicarbazone of formula: <FORM:0855193/VI/1> or its non-toxic water soluble salts (especially sodium, potassium and ammonium salts) in aqueous solution or mixed in chicken feed.
GB7987/57A 1956-04-09 1957-03-11 Improvements in or relating to the manufacture of derivatives of nitrofurfuraldehyde Expired GB855193A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US855193XA 1956-04-09 1956-04-09

Publications (1)

Publication Number Publication Date
GB855193A true GB855193A (en) 1960-11-30

Family

ID=22192152

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7987/57A Expired GB855193A (en) 1956-04-09 1957-03-11 Improvements in or relating to the manufacture of derivatives of nitrofurfuraldehyde

Country Status (1)

Country Link
GB (1) GB855193A (en)

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