GB558009A - Quinoline derivatives - Google Patents
Quinoline derivativesInfo
- Publication number
- GB558009A GB558009A GB620942A GB620942A GB558009A GB 558009 A GB558009 A GB 558009A GB 620942 A GB620942 A GB 620942A GB 620942 A GB620942 A GB 620942A GB 558009 A GB558009 A GB 558009A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyridylquinolines
- pyridine
- isomeric
- bromoquinoline
- aminoquinoline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
Abstract
558,009. Quinoline derivatives. COATES, H., HEILBRON, I. M., HEY, D. H., LAMBERT, A., and IMPERIAL CHEMICAL INDUSTRIES, Ltd. May 8, 1942, No. 6209. [Class 2 (iii)] Pyridylquinolines in which the pyridyl is attached to the phenyl ring, which are useful as spasmolytic agents, are prepared by reaction of corresponding diazotised aminoquinoline which may contain alkyl, alkoxy, halogen, or nitro groups attached to the phenyl ring, with an excess of pyridine or of a pyridine derivative which is liquid at the reaction temperature, e.g. α-methyl- and α-chloropyridines and esters of pyridine carboxylic acids with the lower aliphatic alcohols. Examples give the preparation of isomeric 5- and 8-pyridylquinolines from diazotized 5- and 8-aminoquinoline and pyridine, the picrates of 6-methoxy-8-α-, -#-, and -γ-pyridylquinolines and the free bases, isomeric 8-methoxy-6-pyridylquinolines, and isomeric 8-bromo-6-pyridylquinolines. 6-Amino-8-bromoquinoline is prepared by reduction of 6-nitro-8-bromoquinoline. Specification 267,169, [Class 2 (iii)], is referred to.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB620942A GB558009A (en) | 1942-05-08 | 1942-05-08 | Quinoline derivatives |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB620942A GB558009A (en) | 1942-05-08 | 1942-05-08 | Quinoline derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB558009A true GB558009A (en) | 1943-12-15 |
Family
ID=9810406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB620942A Expired GB558009A (en) | 1942-05-08 | 1942-05-08 | Quinoline derivatives |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB558009A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8026253B2 (en) * | 2009-06-09 | 2011-09-27 | Roche Palo Alto Llc | Quinoline inhibitors of HCV polymerase |
-
1942
- 1942-05-08 GB GB620942A patent/GB558009A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8026253B2 (en) * | 2009-06-09 | 2011-09-27 | Roche Palo Alto Llc | Quinoline inhibitors of HCV polymerase |
| JP2012529461A (en) * | 2009-06-09 | 2012-11-22 | エフ．ホフマン−ラ ロシュ アーゲー | Antiviral heterocyclic compounds |
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