GB530902A - Process for the manufacture of compounds having a bactericidal action - Google Patents
Process for the manufacture of compounds having a bactericidal actionInfo
- Publication number
- GB530902A GB530902A GB19577/39A GB1957739A GB530902A GB 530902 A GB530902 A GB 530902A GB 19577/39 A GB19577/39 A GB 19577/39A GB 1957739 A GB1957739 A GB 1957739A GB 530902 A GB530902 A GB 530902A
- Authority
- GB
- United Kingdom
- Prior art keywords
- sulphanilamide
- phosphamic
- acid
- quinine
- aqueous solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
530,902. Phosphoric acid derivatives of aminobenzenesulphonamide salts. HOFFMANN-LA ROCHE & CO., AKT.-GES., F. July 5, 1939, No. 19577. Convention date, July 29, 1938. [Class 2 (iii)] Compounds having a bactericidal action are prepared by neutralizing phosphoric acid derivatives of 4-amino-benzene sulphonamides with bases which contain at least four carbon atoms and one nitrogen atom and have at least one ring present, the nitrogen atom being either a constituent of a ring or in aliphatic combination or by reacting salts of phosphoric acid derivatives of 4-amino-benzene sulphonamides with salts of such bases. Bases mentioned include quinine, acriflavine or other quinoline and acridine bases. In examples: (1) An aqueous solution of quinine monohydrochloride is reacted with an aqueous solution of the sodium salt of sulphanilamide phosphamic acid to give the quinine salt of sulphanilamide phosphamic acid. (2) The same compound as obtained in example (1) is also obtained by treating an aqueous suspension of quinine with sulphanilamide phosphamic acid. (3) Moist hydroquinine base is neutralized with an aqueous solution of sulphanilamide phosphamic acid. (4) Tyramine hydrochloride and the sodium salt of sulphanilamide phosphamic acid are reacted in aqueous solution to effect salt formation. (5) Emetine base is reacted in an aqueous medium with sulphanilamide phosphamic acid to give the corresponding salt. (6) Hordenine sulphate and sulphanilamide phosphamic acid are reacted together to form the sulphanilamide phosphamate of hordenine.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE530902X | 1938-07-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB530902A true GB530902A (en) | 1940-12-24 |
Family
ID=6554706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB19577/39A Expired GB530902A (en) | 1938-07-29 | 1939-07-05 | Process for the manufacture of compounds having a bactericidal action |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB530902A (en) |
-
1939
- 1939-07-05 GB GB19577/39A patent/GB530902A/en not_active Expired
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