GB272376A - Improvements in or relating to the production of concentrated preparations of vitamine c - Google Patents
Improvements in or relating to the production of concentrated preparations of vitamine cInfo
- Publication number
- GB272376A GB272376A GB2664526A GB2664526A GB272376A GB 272376 A GB272376 A GB 272376A GB 2664526 A GB2664526 A GB 2664526A GB 2664526 A GB2664526 A GB 2664526A GB 272376 A GB272376 A GB 272376A
- Authority
- GB
- United Kingdom
- Prior art keywords
- vitamin
- filtrate
- concentrated
- lead
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
272,376. Agopian, L. A. Oct. 25, 1926. Vitamins.-To obtain concentrated forms of vitamin C, vegetable juice, after initial treatment with metal salts such as acetate of lead and copper, as described in Specification 168,903, is given a further treatment, as follows : The filtrate is neutralized with soda until it turns red with cresol red. The precipitate which is formed contains lead and glucosides &c. associated with the vitamin, and by the use of 5 per cent acetic acid the vitamin with a little impurity is brought into solution. Repetition of the treatment with soda and with acetic acid serves to effect further purification and then after elimination of any lead by sulphuretted hydrogen the filtrate is concentrated in vacuo, mixed with milk of lime and ethyl alcohol to remove organic acids &c., and the final filtrate is concentrated to dryness in vacuo. The powder can be dissolved in glycerine and put into capsules. Purer preparations of the vitamin mav be obtained by subjecting the powder to repeated extractions with absolute ethyl alcohol and then to filtrations after admixture with water.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2664526A GB272376A (en) | 1926-10-25 | 1926-10-25 | Improvements in or relating to the production of concentrated preparations of vitamine c |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2664526A GB272376A (en) | 1926-10-25 | 1926-10-25 | Improvements in or relating to the production of concentrated preparations of vitamine c |
Publications (1)
Publication Number | Publication Date |
---|---|
GB272376A true GB272376A (en) | 1927-06-16 |
Family
ID=10246908
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB2664526A Expired GB272376A (en) | 1926-10-25 | 1926-10-25 | Improvements in or relating to the production of concentrated preparations of vitamine c |
Country Status (1)
Country | Link |
---|---|
GB (1) | GB272376A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2623002A (en) * | 1951-07-13 | 1952-12-23 | Abbott Lab | Ascorbic acid solution |
US5084563A (en) * | 1989-10-21 | 1992-01-28 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Crystalline 2-O-α-D-glucopyranosyl-L-ascorbic acid, and its preparation and uses |
-
1926
- 1926-10-25 GB GB2664526A patent/GB272376A/en not_active Expired
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2623002A (en) * | 1951-07-13 | 1952-12-23 | Abbott Lab | Ascorbic acid solution |
US5084563A (en) * | 1989-10-21 | 1992-01-28 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Crystalline 2-O-α-D-glucopyranosyl-L-ascorbic acid, and its preparation and uses |
US5407812A (en) * | 1989-10-21 | 1995-04-18 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Crystalline 2-O-α-D-glucopyranosyl-L-ascorbic acid, and its preparation and uses |
US5432161A (en) * | 1989-10-21 | 1995-07-11 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Crystalline 2-O-α-d-glucopyranosyl-L-ascorbic acid, and its preparation and uses |
US5843907A (en) * | 1989-10-21 | 1998-12-01 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Pharmaceutical composition containing 2-O-α-d-glucopyranosyl-l-ascorbic acid |
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