GB2523825A - Fabrication of annular microfluidic probe heads - Google Patents

Fabrication of annular microfluidic probe heads Download PDF

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Publication number
GB2523825A
GB2523825A GB1404041.4A GB201404041A GB2523825A GB 2523825 A GB2523825 A GB 2523825A GB 201404041 A GB201404041 A GB 201404041A GB 2523825 A GB2523825 A GB 2523825A
Authority
GB
United Kingdom
Prior art keywords
layouts
layers
layer
machining
hole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB1404041.4A
Other languages
English (en)
Other versions
GB201404041D0 (en
Inventor
Marcel Buerge
Emmanuel Delamarche
Govind Kaigala
Robert Lovchik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
International Business Machines Corp
Original Assignee
International Business Machines Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by International Business Machines Corp filed Critical International Business Machines Corp
Priority to GB1404041.4A priority Critical patent/GB2523825A/en
Publication of GB201404041D0 publication Critical patent/GB201404041D0/en
Priority to GB1616503.7A priority patent/GB2544614B/en
Priority to PCT/IB2015/051075 priority patent/WO2015132686A1/en
Priority to DE112015000711.3T priority patent/DE112015000711B4/de
Priority to JP2016554877A priority patent/JP6482569B2/ja
Priority to CN201580011253.1A priority patent/CN106061599B/zh
Publication of GB2523825A publication Critical patent/GB2523825A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502707—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the manufacture of the container or its components
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0244—Drop counters; Drop formers using pins
    • B01L3/0255—Drop counters; Drop formers using pins characterized by the form or material of the pin tip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0645—Electrodes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1805—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks
    • B01L2300/1827—Conductive heating, heat from thermostatted solids is conducted to receptacles, e.g. heating plates, blocks using resistive heater
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00—Particle spectrometers or separator tubes
    • H01J49/02—Details
    • H01J49/10—Ion sources; Ion guns
    • H01J49/16—Ion sources; Ion guns using surface ionisation, e.g. field-, thermionic- or photo-emission
    • H01J49/165—Electrospray ionisation
    • H01J49/167—Capillaries and nozzles specially adapted therefor

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
GB1404041.4A 2014-03-07 2014-03-07 Fabrication of annular microfluidic probe heads Withdrawn GB2523825A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
GB1404041.4A GB2523825A (en) 2014-03-07 2014-03-07 Fabrication of annular microfluidic probe heads
GB1616503.7A GB2544614B (en) 2014-03-07 2015-02-13 Fabrication of annular microfluidic probe heads
PCT/IB2015/051075 WO2015132686A1 (en) 2014-03-07 2015-02-13 Fabrication of annular microfluidic probe heads
DE112015000711.3T DE112015000711B4 (de) 2014-03-07 2015-02-13 Fertigung von Mikrofluidik-Sondenköpfen
JP2016554877A JP6482569B2 (ja) 2014-03-07 2015-02-13 環状マイクロ流体プローブ・ヘッドの作製
CN201580011253.1A CN106061599B (zh) 2014-03-07 2015-02-13 环形微流体探头的制造

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1404041.4A GB2523825A (en) 2014-03-07 2014-03-07 Fabrication of annular microfluidic probe heads

Publications (2)

Publication Number Publication Date
GB201404041D0 GB201404041D0 (en) 2014-04-23
GB2523825A true GB2523825A (en) 2015-09-09

Family

ID=50554683

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1404041.4A Withdrawn GB2523825A (en) 2014-03-07 2014-03-07 Fabrication of annular microfluidic probe heads
GB1616503.7A Active GB2544614B (en) 2014-03-07 2015-02-13 Fabrication of annular microfluidic probe heads

Family Applications After (1)

Application Number Title Priority Date Filing Date
GB1616503.7A Active GB2544614B (en) 2014-03-07 2015-02-13 Fabrication of annular microfluidic probe heads

Country Status (5)

Country Link
JP (1) JP6482569B2 (de)
CN (1) CN106061599B (de)
DE (1) DE112015000711B4 (de)
GB (2) GB2523825A (de)
WO (1) WO2015132686A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10434510B2 (en) 2017-05-06 2019-10-08 International Business Machines Corporation Microfluidic probe with bypass and control channels
EP3861356A4 (de) 2018-10-01 2022-07-06 Polyvalor, Limited Partnership System und verfahren zur flüssigkeitsausgabe
US11130125B2 (en) 2019-08-06 2021-09-28 Bio-Rad Laboratories, Inc. Prevention and bubble removal from microfluidic devices
US11458467B2 (en) 2019-08-06 2022-10-04 Bio-Rad Laboratories Inc. Structures to define flow confinement shape and confinement stability with uniform aspiration
CN117202990A (zh) * 2021-02-01 2023-12-08 生物辐射实验室股份有限公司 微流体探针

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006014460A2 (en) * 2004-07-06 2006-02-09 University Of Utah Research Foundation Spotting device and method for high concentration spot deposition on microarrays and other microscale devices
WO2010128483A2 (en) * 2009-05-07 2010-11-11 International Business Machines Corporation Multilayer microfluidic probe head and method of fabrication thereof
WO2012056369A1 (en) * 2010-10-29 2012-05-03 International Business Machines Corporation Multilayer microfluidic probe head with immersion channels and fabrication thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050095602A1 (en) * 2003-11-04 2005-05-05 West Jason A. Microfluidic integrated microarrays for biological detection
CA2564876C (en) 2004-04-30 2013-04-16 Bioforce Nanosciences, Inc. Method and apparatus for depositing material onto a surface
US20050247673A1 (en) 2004-05-07 2005-11-10 International Business Machines Corporation Confinement of fluids on surfaces
US7524672B2 (en) * 2004-09-22 2009-04-28 Sandia Corporation Microfluidic microarray systems and methods thereof
JP5063616B2 (ja) 2006-02-03 2012-10-31 インテジェニックス インコーポレイテッド マイクロ流体デバイス
JP2008238097A (ja) 2007-03-28 2008-10-09 Tosoh Corp 滴生成用微小流路集合体装置
US7870616B2 (en) 2007-05-11 2011-01-11 Csem Centre Suisse D'electronique Et De Microtechnique Sa Probe arrangement
EP2240401A1 (de) * 2008-01-04 2010-10-20 The Royal Institution for the Advancement of Learning/McGill University Mikrofluidisches mikroarraysystem und verfahren für die multiplex-analyse von biomolekülen

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006014460A2 (en) * 2004-07-06 2006-02-09 University Of Utah Research Foundation Spotting device and method for high concentration spot deposition on microarrays and other microscale devices
WO2010128483A2 (en) * 2009-05-07 2010-11-11 International Business Machines Corporation Multilayer microfluidic probe head and method of fabrication thereof
WO2012056369A1 (en) * 2010-10-29 2012-05-03 International Business Machines Corporation Multilayer microfluidic probe head with immersion channels and fabrication thereof

Also Published As

Publication number Publication date
DE112015000711B4 (de) 2023-07-20
JP2017516666A (ja) 2017-06-22
CN106061599B (zh) 2017-09-12
WO2015132686A1 (en) 2015-09-11
GB201404041D0 (en) 2014-04-23
GB2544614A (en) 2017-05-24
GB2544614B (en) 2018-09-12
JP6482569B2 (ja) 2019-03-13
DE112015000711T5 (de) 2016-11-03
CN106061599A (zh) 2016-10-26

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