GB2519479B - Compositions comprising crosslinked cation-binding polymers - Google Patents

Compositions comprising crosslinked cation-binding polymers Download PDF

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Publication number
GB2519479B
GB2519479B GB1502802.0A GB201502802A GB2519479B GB 2519479 B GB2519479 B GB 2519479B GB 201502802 A GB201502802 A GB 201502802A GB 2519479 B GB2519479 B GB 2519479B
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Prior art keywords
compositions
crosslinked cation
binding polymers
polymers
binding
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Expired - Fee Related
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GB1502802.0A
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English (en)
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GB2519479A (en
GB201502802D0 (en
Inventor
De Young Linda
F Carroll Stephen
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Relypsa Inc
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Relypsa Inc
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/78—Polymers containing oxygen of acrylic acid or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/755—Polymers containing halogen
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
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    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/04—Acids; Metal salts or ammonium salts thereof
    • C08F220/06—Acrylic acid; Methacrylic acid; Metal salts or ammonium salts thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F220/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and only one being terminated by only one carboxyl radical or a salt, anhydride ester, amide, imide or nitrile thereof
    • C08F220/02—Monocarboxylic acids having less than ten carbon atoms; Derivatives thereof
    • C08F220/10—Esters
    • C08F220/12—Esters of monohydric alcohols or phenols
    • C08F220/16—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms
    • C08F220/18—Esters of monohydric alcohols or phenols of phenols or of alcohols containing two or more carbon atoms with acrylic or methacrylic acids
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F222/00—Copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by a carboxyl radical and containing at least one other carboxyl radical in the molecule; Salts, anhydrides, esters, amides, imides, or nitriles thereof
    • C08F222/10—Esters
    • C08F222/1006—Esters of polyhydric alcohols or polyhydric phenols
    • C08F222/102—Esters of polyhydric alcohols or polyhydric phenols of dialcohols, e.g. ethylene glycol di(meth)acrylate or 1,4-butanediol dimethacrylate

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  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Polymers & Plastics (AREA)
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  • Urology & Nephrology (AREA)
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GB1502802.0A 2012-07-19 2013-07-19 Compositions comprising crosslinked cation-binding polymers Expired - Fee Related GB2519479B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261673707P 2012-07-19 2012-07-19
PCT/US2013/051253 WO2014015240A1 (en) 2012-07-19 2013-07-19 Compositions comprising crosslinked cation-binding polymers

Publications (3)

Publication Number Publication Date
GB201502802D0 GB201502802D0 (en) 2015-04-08
GB2519479A GB2519479A (en) 2015-04-22
GB2519479B true GB2519479B (en) 2020-05-20

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GB1502802.0A Expired - Fee Related GB2519479B (en) 2012-07-19 2013-07-19 Compositions comprising crosslinked cation-binding polymers

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US (1) US20150196585A1 (US07776319-20100817-C00006.png)
EP (1) EP2874633A4 (US07776319-20100817-C00006.png)
JP (3) JP6232062B2 (US07776319-20100817-C00006.png)
KR (1) KR102211670B1 (US07776319-20100817-C00006.png)
CN (2) CN105451746A (US07776319-20100817-C00006.png)
AU (2) AU2013292350B9 (US07776319-20100817-C00006.png)
BR (1) BR112015001230B1 (US07776319-20100817-C00006.png)
CA (1) CA2879425A1 (US07776319-20100817-C00006.png)
DE (1) DE112013003596T5 (US07776319-20100817-C00006.png)
GB (1) GB2519479B (US07776319-20100817-C00006.png)
HK (1) HK1203420A1 (US07776319-20100817-C00006.png)
IN (1) IN2015DN01369A (US07776319-20100817-C00006.png)
MX (2) MX2015000810A (US07776319-20100817-C00006.png)
WO (1) WO2014015240A1 (US07776319-20100817-C00006.png)

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US20150183908A1 (en) * 2012-07-19 2015-07-02 Relypsa, Inc. Compositions comprising crosslinked cation-binding polymers and uses thereof
KR20150088243A (ko) * 2012-10-08 2015-07-31 리립사, 인크. 고혈압 및 고칼륨혈증을 치료하기 위한 칼륨-결합제
US20170022314A1 (en) * 2015-07-24 2017-01-26 Weyerhaeuser Nr Company Grafted crosslinked cellulose
US20170342383A1 (en) 2016-05-27 2017-11-30 Corning Incorporated Lithium disilicate glass-ceramic compositions and methods thereof
EP3717427A1 (en) 2017-11-28 2020-10-07 Corning Incorporated High liquidus viscosity bioactive glass
EP3717426A1 (en) 2017-11-28 2020-10-07 Corning Incorporated Chemically strengthened bioactive glass-ceramics
EP3717030A1 (en) 2017-11-28 2020-10-07 Corning Incorporated Bioactive glass compositions and dentin hypersensitivity remediation
CN111417603B (zh) 2017-11-28 2023-10-31 康宁股份有限公司 生物活性硼酸盐玻璃及其方法
CN108395497B (zh) * 2018-01-22 2021-03-30 中国科学院兰州化学物理研究所 紫外荧光型空间润滑油爬行屏障材料
US20210171693A1 (en) * 2018-04-10 2021-06-10 Arkema Inc. Functional fluoropolymers
WO2020097190A1 (en) * 2018-11-06 2020-05-14 Arizona Board Of Regents On Behalf Of The University Of Arizona Method of personalized treatment for cardiomyopathy and heart failure and associated diseases by measuring edema and cachexia/sarcopenia
JP2021192000A (ja) 2018-12-28 2021-12-16 フォルシアクラリオン・エレクトロニクス株式会社 経路案内方法、端末装置、経路案内システム及びプログラム
US20210186873A1 (en) * 2019-12-19 2021-06-24 Zaki Yusuf Gel compositions for mitigation of burn injuries, kits containing the gel compositions, and associated methods
US11807700B2 (en) * 2020-08-17 2023-11-07 Saudi Arabian Oil Company Electro-responsive hydrogel for reservoir and downhole application
WO2023035274A1 (en) * 2021-09-13 2023-03-16 Waterstone Pharmaceuticals(Wuhan) Co., Ltd. Polymer medicament for treating hyperkalemia and preparation method thereof
CN115570900B (zh) * 2022-09-28 2023-04-07 江西和烁丰新材料有限公司 一种环保型、可长久保存的热敏纸

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US20050031680A1 (en) * 2000-11-20 2005-02-10 Jaime Simon In vivo use of water absorbent polymers
WO2005094384A2 (en) * 2004-03-30 2005-10-13 Ilypsa, Inc. Methods and compositions for treatment of ion imbalances
US20090018136A1 (en) * 2005-12-05 2009-01-15 Oppenheimer Daniel I Methods and compositions for the treatment of vascular disease
US20090042951A1 (en) * 2004-02-20 2009-02-12 Robert Danziger Blood Pressure Reduction in Salt-Sensitive Hypertension
WO2009029829A1 (en) * 2007-08-29 2009-03-05 Sorbent Therapeutics, Inc. Polymeric compositions with enhanced saline holding capacity and their method of preparation and use
WO2010022382A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked polyfluoroacrylic acid and processes for the preparation thereof
US20100104527A1 (en) * 2008-08-22 2010-04-29 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties

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Publication number Priority date Publication date Assignee Title
US5866615A (en) * 1994-11-14 1999-02-02 Bionumerik Pharmaceuticals, Inc. Formulations and methods of use of 2,2'-dithio-bis-ethane sulfonate
US20050031680A1 (en) * 2000-11-20 2005-02-10 Jaime Simon In vivo use of water absorbent polymers
US20090042951A1 (en) * 2004-02-20 2009-02-12 Robert Danziger Blood Pressure Reduction in Salt-Sensitive Hypertension
WO2005094384A2 (en) * 2004-03-30 2005-10-13 Ilypsa, Inc. Methods and compositions for treatment of ion imbalances
US20090018136A1 (en) * 2005-12-05 2009-01-15 Oppenheimer Daniel I Methods and compositions for the treatment of vascular disease
WO2009029829A1 (en) * 2007-08-29 2009-03-05 Sorbent Therapeutics, Inc. Polymeric compositions with enhanced saline holding capacity and their method of preparation and use
WO2010022382A2 (en) * 2008-08-22 2010-02-25 Relypsa, Inc. Crosslinked polyfluoroacrylic acid and processes for the preparation thereof
US20100104527A1 (en) * 2008-08-22 2010-04-29 Relypsa, Inc. Treating hyperkalemia with crosslinked cation exchange polymers of improved physical properties

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JP6600062B2 (ja) 2019-10-30
JP2019034956A (ja) 2019-03-07
CA2879425A1 (en) 2014-01-23
AU2013292350A1 (en) 2015-03-05
KR102211670B1 (ko) 2021-02-02
GB2519479A (en) 2015-04-22
WO2014015240A1 (en) 2014-01-23
BR112015001230A2 (pt) 2017-07-04
MX2020010456A (es) 2020-10-20
AU2013292350B9 (en) 2018-08-23
JP2018024695A (ja) 2018-02-15
CN110051686A (zh) 2019-07-26
JP6423506B2 (ja) 2018-11-14
JP2015528012A (ja) 2015-09-24
BR112015001230B1 (pt) 2020-04-22
MX2015000810A (es) 2015-06-05
IN2015DN01369A (US07776319-20100817-C00006.png) 2015-07-03
AU2013292350B2 (en) 2018-08-09
US20150196585A1 (en) 2015-07-16
GB201502802D0 (en) 2015-04-08
AU2018256550A1 (en) 2018-11-22
EP2874633A4 (en) 2016-06-29
EP2874633A1 (en) 2015-05-27
HK1203420A1 (en) 2015-10-30
KR20150058164A (ko) 2015-05-28
AU2018256550B2 (en) 2020-07-16
DE112013003596T5 (de) 2015-04-09
CN105451746A (zh) 2016-03-30
JP6232062B2 (ja) 2017-11-15

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