GB2492950A - Measuring a luminescent property of a sample using a dual-modulated excitation beam - Google Patents
Measuring a luminescent property of a sample using a dual-modulated excitation beam Download PDFInfo
- Publication number
- GB2492950A GB2492950A GB1111855.1A GB201111855A GB2492950A GB 2492950 A GB2492950 A GB 2492950A GB 201111855 A GB201111855 A GB 201111855A GB 2492950 A GB2492950 A GB 2492950A
- Authority
- GB
- United Kingdom
- Prior art keywords
- text
- sample
- radiation
- signal
- component
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000005284 excitation Effects 0.000 title claims abstract description 19
- 230000005855 radiation Effects 0.000 claims abstract description 123
- 238000001514 detection method Methods 0.000 claims abstract description 54
- 238000005259 measurement Methods 0.000 claims abstract description 23
- 230000000737 periodic effect Effects 0.000 claims description 26
- 238000000034 method Methods 0.000 claims description 16
- 230000003287 optical effect Effects 0.000 claims description 15
- 238000001914 filtration Methods 0.000 claims description 7
- 230000002085 persistent effect Effects 0.000 claims description 3
- 230000003071 parasitic effect Effects 0.000 description 10
- 238000004020 luminiscence type Methods 0.000 description 8
- 238000012545 processing Methods 0.000 description 6
- 230000035945 sensitivity Effects 0.000 description 5
- 230000003321 amplification Effects 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 230000002452 interceptive effect Effects 0.000 description 3
- 238000003199 nucleic acid amplification method Methods 0.000 description 3
- 230000010355 oscillation Effects 0.000 description 3
- 230000003595 spectral effect Effects 0.000 description 3
- 230000037338 UVA radiation Effects 0.000 description 2
- 239000012491 analyte Substances 0.000 description 2
- 238000003556 assay Methods 0.000 description 2
- 238000004166 bioassay Methods 0.000 description 2
- 239000000975 dye Substances 0.000 description 2
- 238000005286 illumination Methods 0.000 description 2
- 238000000691 measurement method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000005424 photoluminescence Methods 0.000 description 2
- 230000003068 static effect Effects 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000764238 Isis Species 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000002526 effect on cardiovascular system Effects 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 238000003018 immunoassay Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000002955 isolation Methods 0.000 description 1
- 230000000704 physical effect Effects 0.000 description 1
- 230000000644 propagated effect Effects 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 230000002123 temporal effect Effects 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
- G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
- G01J3/28—Investigating the spectrum
- G01J3/44—Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
- G01J3/4406—Fluorescence spectrometry
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6408—Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
- G01N2021/6413—Distinction short and delayed fluorescence or phosphorescence
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1111855.1A GB2492950A (en) | 2011-07-11 | 2011-07-11 | Measuring a luminescent property of a sample using a dual-modulated excitation beam |
| PCT/GB2012/051645 WO2013008014A1 (en) | 2011-07-11 | 2012-07-11 | Apparatus and methods for use in measuring a luminescent property |
| RU2014104801/28A RU2014104801A (ru) | 2011-07-11 | 2012-07-11 | Устройство и способы для использования при измерении люминесцентного свойства |
| CN201280044142.7A CN103930766A (zh) | 2011-07-11 | 2012-07-11 | 用于测量发光性质的设备和方法 |
| JP2014519629A JP2014521080A (ja) | 2011-07-11 | 2012-07-11 | ルミネセンス特性の測定に用いる装置及び方法 |
| EP12761757.9A EP2732268A1 (en) | 2011-07-11 | 2012-07-11 | Apparatus and methods for use in measuring a luminescent property |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB1111855.1A GB2492950A (en) | 2011-07-11 | 2011-07-11 | Measuring a luminescent property of a sample using a dual-modulated excitation beam |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| GB201111855D0 GB201111855D0 (en) | 2011-08-24 |
| GB2492950A true GB2492950A (en) | 2013-01-23 |
Family
ID=44544553
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1111855.1A Withdrawn GB2492950A (en) | 2011-07-11 | 2011-07-11 | Measuring a luminescent property of a sample using a dual-modulated excitation beam |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2732268A1 (enExample) |
| JP (1) | JP2014521080A (enExample) |
| CN (1) | CN103930766A (enExample) |
| GB (1) | GB2492950A (enExample) |
| RU (1) | RU2014104801A (enExample) |
| WO (1) | WO2013008014A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9875797B1 (en) | 2016-12-04 | 2018-01-23 | Alex Diggins | Photon memory system |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8975417B2 (en) | 2013-05-27 | 2015-03-10 | Novartis Ag | Pyrazolopyrrolidine derivatives and their use in the treatment of disease |
| EP3361232A1 (en) | 2017-02-09 | 2018-08-15 | Koninklijke Philips N.V. | Optical particle sensor and sensing method |
| JP6831088B1 (ja) * | 2020-07-11 | 2021-02-17 | 株式会社Ｊｉｏｔ | 蛍光検出システム、蛍光検出方法およびコンピュータプログラム |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6297509B1 (en) * | 1996-12-09 | 2001-10-02 | Giesecke & Devrient Gmbh | Device and method for detecting fluorescent and phosphorescent light |
| GB2404013A (en) * | 2003-07-17 | 2005-01-19 | Isis Innovation | Measuring fluorescence lifetime |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5315993A (en) * | 1990-02-16 | 1994-05-31 | The Boc Group, Inc. | Luminescence monitoring with modulation frequency multiplexing |
| US5212386A (en) * | 1991-12-13 | 1993-05-18 | I.S.S. (U.S.A.) Inc. | High speed cross-correlation frequency domain fluorometry-phosphorimetry |
| US5818582A (en) * | 1996-09-19 | 1998-10-06 | Ciencia, Inc. | Apparatus and method for phase fluorometry |
| JP3824233B2 (ja) * | 2003-09-01 | 2006-09-20 | セイコーエプソン株式会社 | バイオセンサ及びバイオセンサの製造方法 |
| WO2005073407A1 (en) * | 2003-10-07 | 2005-08-11 | Ut-Battelle, Llc | Advanced integrated circuit biochip |
| FR2884920B1 (fr) * | 2005-04-21 | 2007-08-10 | Horiba Abx Sa Sa | Dispositif et procede d'analyse multiparametrique d'elements microscopiques |
| EP2002241A1 (en) * | 2006-03-28 | 2008-12-17 | Koninklijke Philips Electronics N.V. | Integrated device having an array of photodetectors and an array of sample sites |
| GB0814909D0 (en) * | 2008-08-14 | 2008-09-24 | Rue De Int Ltd | Phosphorescence detector |
-
2011
- 2011-07-11 GB GB1111855.1A patent/GB2492950A/en not_active Withdrawn
-
2012
- 2012-07-11 JP JP2014519629A patent/JP2014521080A/ja active Pending
- 2012-07-11 EP EP12761757.9A patent/EP2732268A1/en not_active Withdrawn
- 2012-07-11 WO PCT/GB2012/051645 patent/WO2013008014A1/en not_active Ceased
- 2012-07-11 RU RU2014104801/28A patent/RU2014104801A/ru not_active Application Discontinuation
- 2012-07-11 CN CN201280044142.7A patent/CN103930766A/zh active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6297509B1 (en) * | 1996-12-09 | 2001-10-02 | Giesecke & Devrient Gmbh | Device and method for detecting fluorescent and phosphorescent light |
| GB2404013A (en) * | 2003-07-17 | 2005-01-19 | Isis Innovation | Measuring fluorescence lifetime |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9875797B1 (en) | 2016-12-04 | 2018-01-23 | Alex Diggins | Photon memory system |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103930766A (zh) | 2014-07-16 |
| JP2014521080A (ja) | 2014-08-25 |
| GB201111855D0 (en) | 2011-08-24 |
| EP2732268A1 (en) | 2014-05-21 |
| RU2014104801A (ru) | 2015-08-20 |
| WO2013008014A1 (en) | 2013-01-17 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 732E | Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977) |
Free format text: REGISTERED BETWEEN 20140116 AND 20140122 |
|
| WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |