CN103930766A - 用于测量发光性质的设备和方法 - Google Patents

用于测量发光性质的设备和方法 Download PDF

Info

Publication number
CN103930766A
CN103930766A CN201280044142.7A CN201280044142A CN103930766A CN 103930766 A CN103930766 A CN 103930766A CN 201280044142 A CN201280044142 A CN 201280044142A CN 103930766 A CN103930766 A CN 103930766A
Authority
CN
China
Prior art keywords
frequency
sample
radiation
signal
component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280044142.7A
Other languages
English (en)
Chinese (zh)
Inventor
尤金·凡维克
马修·海耶斯
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
XEN BIOFLUIDX Inc
Original Assignee
XEN BIOFLUIDX Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by XEN BIOFLUIDX Inc filed Critical XEN BIOFLUIDX Inc
Publication of CN103930766A publication Critical patent/CN103930766A/zh
Pending legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01JMEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28Investigating the spectrum
    • G01J3/44Raman spectrometry; Scattering spectrometry ; Fluorescence spectrometry
    • G01J3/4406Fluorescence spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6408Fluorescence; Phosphorescence with measurement of decay time, time resolved fluorescence
    • G01N2021/6413Distinction short and delayed fluorescence or phosphorescence

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
CN201280044142.7A 2011-07-11 2012-07-11 用于测量发光性质的设备和方法 Pending CN103930766A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB1111855.1A GB2492950A (en) 2011-07-11 2011-07-11 Measuring a luminescent property of a sample using a dual-modulated excitation beam
GB1111855.1 2011-07-11
PCT/GB2012/051645 WO2013008014A1 (en) 2011-07-11 2012-07-11 Apparatus and methods for use in measuring a luminescent property

Publications (1)

Publication Number Publication Date
CN103930766A true CN103930766A (zh) 2014-07-16

Family

ID=44544553

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280044142.7A Pending CN103930766A (zh) 2011-07-11 2012-07-11 用于测量发光性质的设备和方法

Country Status (6)

Country Link
EP (1) EP2732268A1 (enExample)
JP (1) JP2014521080A (enExample)
CN (1) CN103930766A (enExample)
GB (1) GB2492950A (enExample)
RU (1) RU2014104801A (enExample)
WO (1) WO2013008014A1 (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8975417B2 (en) 2013-05-27 2015-03-10 Novartis Ag Pyrazolopyrrolidine derivatives and their use in the treatment of disease
US9875797B1 (en) 2016-12-04 2018-01-23 Alex Diggins Photon memory system
EP3361232A1 (en) * 2017-02-09 2018-08-15 Koninklijke Philips N.V. Optical particle sensor and sensing method
JP6831088B1 (ja) * 2020-07-11 2021-02-17 株式会社Jiot 蛍光検出システム、蛍光検出方法およびコンピュータプログラム

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5315993A (en) * 1990-02-16 1994-05-31 The Boc Group, Inc. Luminescence monitoring with modulation frequency multiplexing
WO1998012521A1 (en) * 1996-09-19 1998-03-26 Ciencia, Inc. Apparatus and method for phase fluorometry
CN1626680A (zh) * 2003-09-01 2005-06-15 精工爱普生株式会社 生物传感器和生物传感器的制造方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5212386A (en) * 1991-12-13 1993-05-18 I.S.S. (U.S.A.) Inc. High speed cross-correlation frequency domain fluorometry-phosphorimetry
DE19651101A1 (de) * 1996-12-09 1998-06-10 Giesecke & Devrient Gmbh Vorrichtung und Verfahren zur Detektion von fluoreszentem und phosphoreszentem Licht
GB2404013B (en) * 2003-07-17 2006-05-31 Isis Innovation Apparatus for and method of measuring fluorescence lifetime
WO2005073407A1 (en) * 2003-10-07 2005-08-11 Ut-Battelle, Llc Advanced integrated circuit biochip
FR2884920B1 (fr) * 2005-04-21 2007-08-10 Horiba Abx Sa Sa Dispositif et procede d'analyse multiparametrique d'elements microscopiques
US20100230610A1 (en) * 2006-03-28 2010-09-16 Koninklijke Philips Electronics N.V. Integrated device having an array of photodetectors and an array of sample sites
GB0814909D0 (en) * 2008-08-14 2008-09-24 Rue De Int Ltd Phosphorescence detector

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5315993A (en) * 1990-02-16 1994-05-31 The Boc Group, Inc. Luminescence monitoring with modulation frequency multiplexing
WO1998012521A1 (en) * 1996-09-19 1998-03-26 Ciencia, Inc. Apparatus and method for phase fluorometry
CN1626680A (zh) * 2003-09-01 2005-06-15 精工爱普生株式会社 生物传感器和生物传感器的制造方法

Also Published As

Publication number Publication date
GB2492950A (en) 2013-01-23
JP2014521080A (ja) 2014-08-25
RU2014104801A (ru) 2015-08-20
GB201111855D0 (en) 2011-08-24
WO2013008014A1 (en) 2013-01-17
EP2732268A1 (en) 2014-05-21

Similar Documents

Publication Publication Date Title
US7605920B2 (en) Detector system for unidentified substances
CN103930766A (zh) 用于测量发光性质的设备和方法
JP2010501851A5 (enExample)
CN103874915B (zh) 通过荧光法进行体外检测和/或定量的系统
US8357918B2 (en) Apparatus and method for analyzing a fluorescent sample disposed on a substrate
JP2007530916A (ja) 蛍光寿命の測定装置及び方法
JP6703215B1 (ja) 光学測定装置及び光学測定方法
KR20080028777A (ko) 기체 검출 방법 및 기체 검출 장치
CN102713569A (zh) 尤其是用于血糖确定的测量系统和测量方法
US20230204510A1 (en) Optical detector
US20150198528A1 (en) Assay detection system
US20100141938A1 (en) Method and apparatus for detection of analytes
KR20120107976A (ko) 형광 측정 장치 및 형광 측정 방법
JP2014521080A5 (enExample)
US7622723B2 (en) System for spore detection
US20090218515A1 (en) Eliminating fluorescence background noise
Vita et al. Deep-ultraviolet light-emitting diodes for frequency domain measurements of fluorescence lifetime in basic biofluorophores
Vitta et al. Frequency-domain fluorometry in the presence of high in-phase background
JP2001159601A (ja) 光学的測定装置
KR100940305B1 (ko) 휴대용 특수파장 검출장치와 이를 이용한 검출방법
CN217981257U (zh) 一种荧光检测电路及核酸poct检测装置
TWI475213B (zh) 螢光檢測方法
JP2006331116A (ja) 蛍光検出装置
CN109324031B (zh) 一种通过特定调制的激发光来分辨拉曼信号的方法
Iwata et al. A proposal of a pseudo-lock-in light-detection scheme by sinusoidal modulation of bias voltages applied to two dynodes in a photomultiplier tube

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WD01 Invention patent application deemed withdrawn after publication

Application publication date: 20140716

WD01 Invention patent application deemed withdrawn after publication