GB2205834B - 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds - Google Patents

3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds

Info

Publication number
GB2205834B
GB2205834B GB8813951A GB8813951A GB2205834B GB 2205834 B GB2205834 B GB 2205834B GB 8813951 A GB8813951 A GB 8813951A GB 8813951 A GB8813951 A GB 8813951A GB 2205834 B GB2205834 B GB 2205834B
Authority
GB
United Kingdom
Prior art keywords
dicarboxy
hydroxy
amino
indole compounds
indole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8813951A
Other languages
English (en)
Other versions
GB2205834A (en
GB8813951D0 (en
Inventor
Pieter Johannes Van Wyk
Louis Gabriel Jozua Ackerman
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
South African Inventions Development Corp
Original Assignee
South African Inventions Development Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by South African Inventions Development Corp filed Critical South African Inventions Development Corp
Publication of GB8813951D0 publication Critical patent/GB8813951D0/en
Publication of GB2205834A publication Critical patent/GB2205834A/en
Application granted granted Critical
Publication of GB2205834B publication Critical patent/GB2205834B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Indole Compounds (AREA)
  • Seasonings (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB8813951A 1987-06-15 1988-06-13 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds Expired - Lifetime GB2205834B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA874290 1987-06-15
ZA874288 1987-06-15
ZA874289 1987-06-15

Publications (3)

Publication Number Publication Date
GB8813951D0 GB8813951D0 (en) 1988-07-20
GB2205834A GB2205834A (en) 1988-12-21
GB2205834B true GB2205834B (en) 1990-10-31

Family

ID=27420944

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8813951A Expired - Lifetime GB2205834B (en) 1987-06-15 1988-06-13 3-(1-amino-1,3-dicarboxy-3-hydroxy-but-4-yl)-indole compounds

Country Status (5)

Country Link
US (2) US4975298A (enExample)
JP (1) JP2522689B2 (enExample)
CH (1) CH675243A5 (enExample)
DE (1) DE3820166C2 (enExample)
GB (1) GB2205834B (enExample)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2063443T3 (es) * 1990-01-19 1995-01-01 Technology Finance Corp Procedimiento para la produccion de 3-(1-amino-1,3-dicarboxi-3-hidroxi-but-4-il) indol.
US5994559A (en) * 1998-08-06 1999-11-30 The Board Of Governors For Higher Education, State Of Rhode Island And Providence Plantations Synthesis of monatin-A high intensity natural sweetener
US6348434B1 (en) * 1999-07-01 2002-02-19 Basf Aktiengesellschaft Herbicidal emulsifiable concentrate
RU2303030C2 (ru) 2001-11-30 2007-07-20 Адзиномото Ко., Инк. Кристаллы соли неприродного стереоизомера монатина и их применение
JP4196832B2 (ja) 2001-12-27 2008-12-17 味の素株式会社 グルタミン酸化合物及びそれらの製造中間体の製造方法並びにそのための新規中間体
RU2280078C2 (ru) * 2001-12-27 2006-07-20 Адзиномото Ко., Инк. Способ получения производного глютамата (варианты) и способ получения монатина
US7297800B2 (en) * 2001-12-27 2007-11-20 Ajinomoto Co., Inc. Process of producing glutamate derivatives
RU2305677C2 (ru) * 2001-12-27 2007-09-10 Адзиномото Ко., Инк. Способы получения производных глутаминовой кислоты, способы получения промежуточных соединений и новое промежуточное соединение для данных способов
GEP20084387B (en) * 2002-04-23 2008-06-10 Cargill Inc Method for production of monatin from tryptophan and indole-3-lactic acid
US8372989B2 (en) 2002-04-23 2013-02-12 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
US7572607B2 (en) * 2002-04-23 2009-08-11 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of monatin and its precursors
JP4670347B2 (ja) * 2002-08-26 2011-04-13 味の素株式会社 新規アルドラーゼおよび置換α−ケト酸の製造方法
BR0316927A (pt) 2002-12-09 2005-10-18 Ajinomoto Kk Proteìna, métodos para produzir um derivado de ácido glutâmico oticamente ativo e para produzir uma proteìna tendo uma atividade de d-aminotransferase, dna, célula
AU2003301508A1 (en) * 2003-01-09 2004-08-23 Ajinomoto Co., Inc. Processes for producing glutamic acid derivative and pyroglutamic acid derivative and novel intermediate for production
WO2005014839A2 (en) * 2003-08-01 2005-02-17 Cargill, Incorporated Monatin tabletop sweetener compositions and methods of making same
EP1657985A1 (en) * 2003-08-25 2006-05-24 Cargill Inc. Beverage compositions comprising monatin and methods of making same
ATE498691T1 (de) 2003-10-21 2011-03-15 Cargill Inc Herstellung von monatin und monatinvorstufen
JP5113978B2 (ja) * 2003-11-21 2013-01-09 味の素株式会社 グルタミン酸誘導体の有機アミン塩及びその利用
US7935377B2 (en) 2004-06-04 2011-05-03 Ajinomoto Co., Inc. Crystals of free (2R, 4R)-monatin and use thereof
CA2506247C (en) 2004-06-07 2012-02-21 Ajinomoto Co., Inc. Novel aldolase, and method for producing optically active ihog and monatin
KR101216575B1 (ko) * 2004-07-14 2012-12-31 아지노모토 가부시키가이샤 (2ｒ,4ｒ)-모나틴 칼륨 염 결정 및 이를 함유하는 감미료조성물
US7180370B2 (en) * 2004-09-01 2007-02-20 Micron Technology, Inc. CMOS amplifiers with frequency compensating capacitors
CN101223444B (zh) * 2005-04-20 2013-04-24 嘉吉有限公司 在体内分泌莫纳甜的方法
US8158389B2 (en) * 2005-04-20 2012-04-17 Cargill, Incorporated Products and methods for in vivo secretion of monatin
US8076108B2 (en) * 2005-04-26 2011-12-13 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
US7582455B2 (en) * 2005-04-26 2009-09-01 Cargill, Incorporated Polypeptides and biosynthetic pathways for the production of stereoisomers of monatin and their precursors
EP2322643B1 (en) 2006-03-07 2014-07-09 Cargill, Incorporated Aldolases, nucleic acids encoding them and methods for making and using them
US20090198072A1 (en) * 2006-05-24 2009-08-06 Cargill, Incorporated Methods and systems for increasing production of equilibrium reactions
CN101490249A (zh) 2006-05-24 2009-07-22 嘉吉公司 提高平衡反应的产量的方法和系统
CN101239941B (zh) 2007-02-08 2012-02-29 味之素株式会社 光学活性化合物的制造方法
US8367847B2 (en) * 2007-10-01 2013-02-05 Cargill, Incorporated Production of monatin enantiomers
US8003361B2 (en) * 2007-10-01 2011-08-23 Cargill Incorporated Production of monatin enantiomers
US8076107B2 (en) * 2007-10-01 2011-12-13 Cargill, Incorporated Production of monatin stereoisomers
US20120076899A1 (en) 2009-05-28 2012-03-29 Cargill, Incorporated Shelf stable monatin sweetened beverage
US8771997B2 (en) 2011-04-20 2014-07-08 Ajinomoto Co., Inc. Method for producing monatin using an L-amino acid aminotransferase

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3535336A (en) * 1968-04-08 1970-10-20 Lilly Co Eli 6-(trifluoromethyl)tryptophane

Also Published As

Publication number Publication date
US4975298A (en) 1990-12-04
GB2205834A (en) 1988-12-21
GB8813951D0 (en) 1988-07-20
DE3820166A1 (de) 1988-12-29
US5128164A (en) 1992-07-07
CH675243A5 (enExample) 1990-09-14
JPS6425757A (en) 1989-01-27
DE3820166C2 (de) 1998-08-13
JP2522689B2 (ja) 1996-08-07

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Legal Events

Date Code Title Description
732E Amendments to the register in respect of changes of name or changes affecting rights (sect. 32/1977)
PE20 Patent expired after termination of 20 years

Expiry date: 20080612