GB2165249A - Preparation of mitomycin derivatives - Google Patents

Preparation of mitomycin derivatives Download PDF

Info

Publication number
GB2165249A
GB2165249A GB08524725A GB8524725A GB2165249A GB 2165249 A GB2165249 A GB 2165249A GB 08524725 A GB08524725 A GB 08524725A GB 8524725 A GB8524725 A GB 8524725A GB 2165249 A GB2165249 A GB 2165249A
Authority
GB
United Kingdom
Prior art keywords
mitomycin
electrophile
amino
methoxymitosane
pyridine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
GB08524725A
Other languages
English (en)
Other versions
GB8524725D0 (en
Inventor
Henry She Lai Wong
Takushi Kaneko
Terrence William Doyle
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GB8524725D0 publication Critical patent/GB8524725D0/en
Publication of GB2165249A publication Critical patent/GB2165249A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB08524725A 1984-10-09 1985-10-08 Preparation of mitomycin derivatives Withdrawn GB2165249A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US65912884A 1984-10-09 1984-10-09

Publications (2)

Publication Number Publication Date
GB8524725D0 GB8524725D0 (en) 1985-11-13
GB2165249A true GB2165249A (en) 1986-04-09

Family

ID=24644154

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08524725A Withdrawn GB2165249A (en) 1984-10-09 1985-10-08 Preparation of mitomycin derivatives

Country Status (7)

Country Link
JP (1) JPS6191189A (sv)
DK (1) DK460285A (sv)
FR (1) FR2571373A1 (sv)
GB (1) GB2165249A (sv)
HU (1) HUT38943A (sv)
IT (1) IT1187749B (sv)
SE (1) SE8504659L (sv)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0265050A1 (en) * 1986-08-26 1988-04-27 Kyowa Hakko Kogyo Kabushiki Kaisha Mitomycin derivatives
EP0294828A2 (en) * 1987-06-12 1988-12-14 Bristol-Myers Squibb Company Mitomycin analogs, a process for preparing them and pharmaceutical compositions

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284380B1 (en) * 1987-03-25 1992-06-10 Kyowa Hakko Kogyo Kabushiki Kaisha Mitomycin derivatives

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2106096A (en) * 1981-05-15 1983-04-07 University Patents Inc Mitomycin derivatives their preparation and use
GB2151627A (en) * 1983-12-23 1985-07-24 Bristol Myers Co 7-acylamino mitosanes

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2106096A (en) * 1981-05-15 1983-04-07 University Patents Inc Mitomycin derivatives their preparation and use
GB2151627A (en) * 1983-12-23 1985-07-24 Bristol Myers Co 7-acylamino mitosanes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
JOURNAL OF MEDICINAL CHEMISTRY 26 (1) 16-20 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0265050A1 (en) * 1986-08-26 1988-04-27 Kyowa Hakko Kogyo Kabushiki Kaisha Mitomycin derivatives
EP0294828A2 (en) * 1987-06-12 1988-12-14 Bristol-Myers Squibb Company Mitomycin analogs, a process for preparing them and pharmaceutical compositions
EP0294828A3 (en) * 1987-06-12 1990-05-09 Bristol-Myers Squibb Company Mitomycin analogs, a process for preparing them and pharmaceutical compositions
US5374739A (en) * 1987-06-12 1994-12-20 Bristol-Myers Squibb Company Mitomycin analogs

Also Published As

Publication number Publication date
DK460285D0 (da) 1985-10-08
DK460285A (da) 1986-04-10
JPS6191189A (ja) 1986-05-09
IT8522385A0 (it) 1985-10-08
HUT38943A (en) 1986-07-28
SE8504659L (sv) 1986-04-10
FR2571373A1 (fr) 1986-04-11
GB8524725D0 (en) 1985-11-13
SE8504659D0 (sv) 1985-10-08
IT1187749B (it) 1987-12-23

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Legal Events

Date Code Title Description
WAP Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1)