SE8504659D0 - Process for preparation of n?727-substituted mitomycin c derivatives - Google Patents
Process for preparation of n?727-substituted mitomycin c derivativesInfo
- Publication number
- SE8504659D0 SE8504659D0 SE8504659A SE8504659A SE8504659D0 SE 8504659 D0 SE8504659 D0 SE 8504659D0 SE 8504659 A SE8504659 A SE 8504659A SE 8504659 A SE8504659 A SE 8504659A SE 8504659 D0 SE8504659 D0 SE 8504659D0
- Authority
- SE
- Sweden
- Prior art keywords
- methoxymitosane
- amino
- derivatives
- mitomycin
- preparation
- Prior art date
Links
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical class C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 title abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 2
- HRHKSTOGXBBQCB-UHFFFAOYSA-N Mitomycin E Natural products O=C1C(N)=C(C)C(=O)C2=C1C(COC(N)=O)C1(OC)C3N(C)C3CN12 HRHKSTOGXBBQCB-UHFFFAOYSA-N 0.000 abstract 1
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 150000001450 anions Chemical class 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000012039 electrophile Substances 0.000 abstract 1
- HRHKSTOGXBBQCB-VFWICMBZSA-N methylmitomycin Chemical compound O=C1C(N)=C(C)C(=O)C2=C1[C@@H](COC(N)=O)[C@@]1(OC)[C@H]3N(C)[C@H]3CN12 HRHKSTOGXBBQCB-VFWICMBZSA-N 0.000 abstract 1
- 229960004857 mitomycin Drugs 0.000 abstract 1
- 230000000269 nucleophilic effect Effects 0.000 abstract 1
- 229950004406 porfiromycin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
- C07D487/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65912884A | 1984-10-09 | 1984-10-09 |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8504659D0 true SE8504659D0 (sv) | 1985-10-08 |
SE8504659L SE8504659L (sv) | 1986-04-10 |
Family
ID=24644154
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8504659A SE8504659L (sv) | 1984-10-09 | 1985-10-08 | Forfarande for framstellning av n?72-substituerade derivat av mitomucin c |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS6191189A (sv) |
DK (1) | DK460285A (sv) |
FR (1) | FR2571373A1 (sv) |
GB (1) | GB2165249A (sv) |
HU (1) | HUT38943A (sv) |
IT (1) | IT1187749B (sv) |
SE (1) | SE8504659L (sv) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6354380A (ja) * | 1986-08-26 | 1988-03-08 | Kyowa Hakko Kogyo Co Ltd | マイトマイシン誘導体 |
DE3871836T2 (de) * | 1987-03-25 | 1993-01-14 | Kyowa Hakko Kogyo Kk | Mitomycin-derivate. |
IL86665A0 (en) * | 1987-06-12 | 1988-11-30 | Bristol Myers Co | Mitomycin analogs |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ199617A (en) * | 1981-05-15 | 1985-08-30 | University Patents Inc | Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions |
US4642352A (en) * | 1983-12-23 | 1987-02-10 | Bristol-Myers Company | Acylamino mitosanes |
-
1985
- 1985-09-03 FR FR8513072A patent/FR2571373A1/fr active Pending
- 1985-10-08 HU HU853906A patent/HUT38943A/hu unknown
- 1985-10-08 JP JP60224631A patent/JPS6191189A/ja active Pending
- 1985-10-08 DK DK460285A patent/DK460285A/da not_active Application Discontinuation
- 1985-10-08 IT IT8522385A patent/IT1187749B/it active
- 1985-10-08 GB GB08524725A patent/GB2165249A/en not_active Withdrawn
- 1985-10-08 SE SE8504659A patent/SE8504659L/sv not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GB8524725D0 (en) | 1985-11-13 |
DK460285D0 (da) | 1985-10-08 |
DK460285A (da) | 1986-04-10 |
JPS6191189A (ja) | 1986-05-09 |
IT8522385A0 (it) | 1985-10-08 |
GB2165249A (en) | 1986-04-09 |
SE8504659L (sv) | 1986-04-10 |
HUT38943A (en) | 1986-07-28 |
IT1187749B (it) | 1987-12-23 |
FR2571373A1 (fr) | 1986-04-11 |
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Legal Events
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NAV | Patent application has lapsed |
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